ID I6TVC0_NOTNE Unreviewed; 289 AA. AC I6TVC0; DT 03-OCT-2012, integrated into UniProtKB/TrEMBL. DT 03-OCT-2012, sequence version 1. DT 27-MAR-2024, entry version 17. DE SubName: Full=Polycystic kidney disease 1 {ECO:0000313|EMBL:AFM80376.1}; DE Flags: Fragment; OS Notothenia neglecta (Yellowbelly rockcod) (Notothenia coriiceps neglecta). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Eupercaria; Perciformes; Notothenioidei; Nototheniidae; Notothenia. OX NCBI_TaxID=202063 {ECO:0000313|EMBL:AFM80376.1}; RN [1] {ECO:0000313|EMBL:AFM80376.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=TA13 {ECO:0000313|EMBL:AFM80376.1}; RA Dettai A., Berkani M., Lautredou A.C., Couloux A., Lecointre G., RA Ozouf-Costaz C., Gallut C.; RT "Tracking the elusive monophyly of nototheniid fishes (Teleostei) with RT multiple mitochondrial and nuclear markers."; RL Mar. Genomics 0:0-0(2012). CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JQ688757; AFM80376.1; -; Genomic_DNA. DR AlphaFoldDB; I6TVC0; -. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW. DR CDD; cd00146; PKD; 3. DR Gene3D; 2.60.40.10; Immunoglobulins; 3. DR InterPro; IPR013783; Ig-like_fold. DR InterPro; IPR022409; PKD/Chitinase_dom. DR InterPro; IPR000601; PKD_dom. DR InterPro; IPR035986; PKD_dom_sf. DR PANTHER; PTHR46730; POLYCYSTIN-1; 1. DR PANTHER; PTHR46730:SF3; POLYCYSTIN-1; 1. DR Pfam; PF00801; PKD; 2. DR Pfam; PF18911; PKD_4; 1. DR SMART; SM00089; PKD; 3. DR SUPFAM; SSF49299; PKD domain; 3. DR PROSITE; PS50093; PKD; 3. PE 4: Predicted; KW Membrane {ECO:0000256|ARBA:ARBA00023136}; KW Repeat {ECO:0000256|ARBA:ARBA00022737}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}. FT DOMAIN 19..89 FT /note="PKD" FT /evidence="ECO:0000259|PROSITE:PS50093" FT DOMAIN 110..156 FT /note="PKD" FT /evidence="ECO:0000259|PROSITE:PS50093" FT DOMAIN 185..243 FT /note="PKD" FT /evidence="ECO:0000259|PROSITE:PS50093" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:AFM80376.1" FT NON_TER 289 FT /evidence="ECO:0000313|EMBL:AFM80376.1" SQ SEQUENCE 289 AA; 31907 MW; 6CD2BE29ED78C01C CRC64; ILTHVDIQTE PQLLLTDKSA EFEAHPLPSP YGIHYDWRFG DGSPLMQGRR VAHTYAQSGV FNVCVSVNNT ISSMEACAEV FVFEEIDDLT AKSSSPTELH SPTVVQARLG SGNNITWTFS MGDGEMYTTS TPHMSHKYVT EGNYTVNVTA ANAVSSGWTL VAVQVFVFQV VRMEPSGCVQ ERTLVNFQAW VSGNASAHLY EWSFGDGSPN ETHQGNPTVS HTYWTSGKYH LSLRLSSGVN KATKANFFNW VCVQPALTNI SLSLDKSHYA VGEKISFQTR AQPESNYSY //