ID I6QDQ4_9HIV1 Unreviewed; 90 AA. AC I6QDQ4; DT 03-OCT-2012, integrated into UniProtKB/TrEMBL. DT 03-OCT-2012, sequence version 1. DT 06-JUL-2016, entry version 15. DE RecName: Full=Protein Rev {ECO:0000256|SAAS:SAAS00132807}; DE Flags: Fragment; GN Name=rev {ECO:0000313|EMBL:AFK88280.1}; OS Human immunodeficiency virus 1. OC Viruses; Retro-transcribing viruses; Retroviridae; Orthoretrovirinae; OC Lentivirus; Primate lentivirus group. OX NCBI_TaxID=11676 {ECO:0000313|EMBL:AFK88280.1}; OH NCBI_TaxID=9606; Homo sapiens (Human). RN [1] {ECO:0000313|EMBL:AFK88280.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=CH58wk4.3B3 {ECO:0000313|EMBL:AFK88280.1}; RX PubMed=22693447; DOI=10.1371/journal.ppat.1002721; RA Bar K.J., Tsao C.Y., Iyer S.S., Decker J.M., Yang Y., Bonsignori M., RA Chen X., Hwang K.K., Montefiori D.C., Liao H.X., Hraber P., RA Fischer W., Li H., Wang S., Sterrett S., Keele B.F., Ganusov V.V., RA Perelson A.S., Korber B.T., Georgiev I., McLellan J.S., Pavlicek J.W., RA Gao F., Haynes B.F., Hahn B.H., Kwong P.D., Shaw G.M.; RT "Early Low-Titer Neutralizing Antibodies Impede HIV-1 Replication and RT Select for Virus Escape."; RL PLoS Pathog. 8:E1002721-E1002721(2012). CC -!- SUBUNIT: Homomultimer; when bound to the RRE. Multimeric assembly CC is essential for activity. {ECO:0000256|SAAS:SAAS00592583}. CC -!- SUBCELLULAR LOCATION: Host cytoplasm CC {ECO:0000256|SAAS:SAAS00592585}. CC -!- SUBCELLULAR LOCATION: Host nucleus, host nucleolus CC {ECO:0000256|SAAS:SAAS00592582}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JQ957745; AFK88280.1; -; Genomic_RNA. DR GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0044196; C:host cell nucleolus; IEA:UniProtKB-SubCell. DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW. DR GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; IEA:InterPro. DR GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW. DR InterPro; IPR000625; REV_protein. DR Pfam; PF00424; REV; 1. PE 4: Predicted; KW Host cytoplasm {ECO:0000256|SAAS:SAAS00486079}; KW Host nucleus {ECO:0000256|SAAS:SAAS00486044}; KW mRNA transport {ECO:0000256|SAAS:SAAS00486068}; KW RNA-binding {ECO:0000256|SAAS:SAAS00486057}; KW Transport {ECO:0000256|SAAS:SAAS00486084}. FT NON_TER 1 1 {ECO:0000313|EMBL:AFK88280.1}. SQ SEQUENCE 90 AA; 9975 MW; 0205AEE207F29122 CRC64; PPPSSEGTRQ ARRNRRRRWR ERQRQIQRIS GWILSTYLGR SAEPVPLPLP PLERLTLGSN EDCGTSGSQG VGSPQVLVES PAVLESGTKE //