ID I3ZQV5_PLAVI Unreviewed; 476 AA. AC I3ZQV5; DT 05-SEP-2012, integrated into UniProtKB/TrEMBL. DT 05-SEP-2012, sequence version 1. DT 29-MAY-2024, entry version 27. DE SubName: Full=Merozoite surface protein 8 {ECO:0000313|EMBL:AFL93307.1}; DE Flags: Fragment; OS Plasmodium vivax (malaria parasite P. vivax). OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium). OX NCBI_TaxID=5855 {ECO:0000313|EMBL:AFL93307.1}; RN [1] {ECO:0000313|EMBL:AFL93307.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Vietnam Palo Alto {ECO:0000313|EMBL:AFL93307.1}; RX PubMed=22414917; DOI=10.1016/j.meegid.2012.02.009; RA Pacheco M.A., Elango A.P., Rahman A.A., Fisher D., Collins W.E., RA Barnwell J.W., Escalante A.A.; RT "Evidence of purifying selection on merozoite surface protein 8 (MSP8) and RT 10 (MSP10) in Plasmodium spp."; RL Infect. Genet. Evol. 12:978-986(2012). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JQ246006; AFL93307.1; -; Genomic_DNA. DR AlphaFoldDB; I3ZQV5; -. DR VEuPathDB; PlasmoDB:PVP01_1032600; -. DR VEuPathDB; PlasmoDB:PVPAM_100039200; -. DR VEuPathDB; PlasmoDB:PVW1_100056700; -. DR VEuPathDB; PlasmoDB:PVX_097625; -. DR Gene3D; 2.10.25.10; Laminin; 1. DR InterPro; IPR000742; EGF-like_dom. DR InterPro; IPR024731; EGF_dom. DR InterPro; IPR024730; MSP1_EGF_1. DR Pfam; PF12947; EGF_3; 1. DR Pfam; PF12946; EGF_MSP1_1; 1. DR SMART; SM00181; EGF; 2. DR SUPFAM; SSF57196; EGF/Laminin; 2. PE 4: Predicted; KW Merozoite {ECO:0000313|EMBL:AFL93307.1}; Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1..18 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 19..476 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5003684958" FT DOMAIN 378..417 FT /note="EGF-like" FT /evidence="ECO:0000259|SMART:SM00181" FT DOMAIN 423..460 FT /note="EGF-like" FT /evidence="ECO:0000259|SMART:SM00181" FT REGION 24..126 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 24..65 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 66..90 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 91..119 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:AFL93307.1" FT NON_TER 476 FT /evidence="ECO:0000313|EMBL:AFL93307.1" SQ SEQUENCE 476 AA; 53403 MW; 0CDA21FA164A8172 CRC64; AQIVIFCLFG LLSYRCGAEG NVSPPNFNDN RVNGNNGNKG NGNDNDVPSF IGGNNNNVND NNDDNIFNKN GKDVTRNDGD AKDGENRNNK KNENGSGSNE NNSIANADNG SGKSDANANQ IDEDGNKMDE ASLKKILKIV DEMENIQGLL DGDYSILDKY SVKLVDEDDG ETNKRKIIGE YDLKMLKNIL LFREKISRVC ENKYNKNLPV LLKKCSNVDD PKLSKSREKI KKGLAKNNMS IEDFVVGLLE DLFEKINEHF IKDDSFDLSD YLADFELINY IIMHETSELI DELLNIIESM NFRLESGSLE KMVKSAESGM NLNCKMKEDI IHLLKKSSAK FFKIEIDRKT KMIYPVQATH KGANMKQLAL SFLQKNNVCE HKKCPLNSNC YVINGEEVCR CLPGFSDVKI DNVMNCVRDD TLDCSNNNGG CDVNATCTLI DKKIVCECKD NFEGDGIYCS YSIFNSINNF IFLILL //