ID I2IMD5_9BURK Unreviewed; 563 AA. AC I2IMD5; DT 11-JUL-2012, integrated into UniProtKB/TrEMBL. DT 11-JUL-2012, sequence version 1. DT 26-FEB-2020, entry version 33. DE RecName: Full=DNA helicase {ECO:0000256|SAAS:SAAS00413339}; DE EC=3.6.4.12 {ECO:0000256|SAAS:SAAS00413339}; GN ORFNames=BCh11DRAFT_07437 {ECO:0000313|EMBL:EIF31887.1}; OS Burkholderia sp. Ch1-1. OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; OC Burkholderiaceae; Burkholderia. OX NCBI_TaxID=243261 {ECO:0000313|EMBL:EIF31887.1, ECO:0000313|Proteomes:UP000005779}; RN [1] {ECO:0000313|Proteomes:UP000005779} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Ch1-1 {ECO:0000313|Proteomes:UP000005779}; RG US DOE Joint Genome Institute (JGI-PGF); RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., RA Pitluck S., Land M.L., Hauser L., Bradfield C., Sheety A., Cheng S., RA Chain P., Denef V., Hickey W.J., Woyke T.; RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:EIF31887.1, ECO:0000313|Proteomes:UP000005779} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Ch1-1 {ECO:0000313|EMBL:EIF31887.1, RC ECO:0000313|Proteomes:UP000005779}; RG US DOE Joint Genome Institute; RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., RA Peters L., Ovchinnikova G., Teshima H., Detter J.C., Han C., Tapia R., RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Bradfield C., RA Sheety A., Cheng S., Chain P., Denef V., Hickey W., Woyke T.; RT "Improved High-Quality Draft sequence of Burkholderia sp. Ch1-1."; RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065, CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12; CC Evidence={ECO:0000256|SAAS:SAAS01129065}; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JH603161; EIF31887.1; -; Genomic_DNA. DR RefSeq; WP_007182579.1; NZ_JH603161.1. DR EnsemblBacteria; EIF31887; EIF31887; BCh11DRAFT_07437. DR HOGENOM; CLU_004585_5_10_4; -. DR Proteomes; UP000005779; Unassembled WGS sequence. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0003678; F:DNA helicase activity; IEA:UniProtKB-EC. DR Gene3D; 1.10.10.160; -; 1. DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf. DR InterPro; IPR014017; DNA_helicase_UvrD-like_C. DR InterPro; IPR000212; DNA_helicase_UvrD/REP. DR InterPro; IPR027417; P-loop_NTPase. DR InterPro; IPR014016; UvrD-like_ATP-bd. DR PANTHER; PTHR11070; PTHR11070; 1. DR Pfam; PF13361; UvrD_C; 2. DR SUPFAM; SSF52540; SSF52540; 1. DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1. DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1. PE 4: Predicted; KW ATP-binding {ECO:0000256|SAAS:SAAS00146071}; KW DNA-binding {ECO:0000256|SAAS:SAAS00745286}; KW Helicase {ECO:0000256|SAAS:SAAS00553650, ECO:0000313|EMBL:EIF31887.1}; KW Hydrolase {ECO:0000256|SAAS:SAAS00146062}; KW Nucleotide-binding {ECO:0000256|SAAS:SAAS00145996}. FT DOMAIN 2..253 FT /note="UvrD-like helicase ATP-binding" FT /evidence="ECO:0000259|PROSITE:PS51198" FT DOMAIN 254..502 FT /note="UvrD-like helicase C-terminal" FT /evidence="ECO:0000259|PROSITE:PS51217" SQ SEQUENCE 563 AA; 61727 MW; 8C523CBDA1B070CC CRC64; MLDGLNPKQR EVAELRRPCV AIACPGAGKT KTIAAKAALL LGDPHTVVGA VTFSKDAAVE LRDRILALAG AGAKSRLIAG TFHSLANRQL GKRDIATDGD RAGLIARVLA ELGLQWKTEE VIPVIERIKT NFGRVEDGGP DAQLYHAYQE ALARNGKIDF QDMLRLAVAG MEAGDIEPYR FTDLLVDEFQ DTDPLQYRWV ELHADAGARV TVVGDDDQSI YGFRAALGFR GMESFAASFN AQRIVLGSNY RCRSEILAAA DRVIRNNVDR IAKVLHAERG AGGAIATRRF DDEYSDAVAA VEQLQPLLAA GNSCAILART NRILDPIEAV CRSHGVPYYR ASGASVLNGP QGALMCNLLQ IAEGRKQNGL DAVLGYTGMS STHLGALHRD MGAVLIQRAK KDLVALGLSD DTASAYRAFM KRLAEWTQMC ERRFYALALD GVLEMMMTYA RDDRAKRAIQ ATYDVLSRLN GTFAERIEYL KRDNNKPADG ALVLTTMHSS KGLEWNHVWI TRAEEGIVPD EKSTESEERR LFYVAMTRAR DTLTIATIKK NPVSRFVIES AIA //