ID I1YN96_CHAHI Unreviewed; 323 AA. AC I1YN96; DT 11-JUL-2012, integrated into UniProtKB/TrEMBL. DT 11-JUL-2012, sequence version 1. DT 03-OCT-2012, entry version 3. DE RecName: Full=NADH-ubiquinone oxidoreductase chain 2; DE EC=1.6.5.3; DE Flags: Fragment; GN Name=ND2; OS Chaetodipus hispidus (Hispid pocket mouse). OG Mitochondrion. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Heteromyidae; Perognathinae; Chaetodipus. OX NCBI_TaxID=38665; RN [1] RP NUCLEOTIDE SEQUENCE. RA Andersen J.J., Light J.E.; RT "Phylogeography and subspecies revision of the hispid pocket mouse, RT Chaetodipus hispidus (Rodentia: Heteromyidae)."; RL J. Mammal. 93:1195-1215(2012). CC -!- FUNCTION: Core subunit of the mitochondrial membrane respiratory CC chain NADH dehydrogenase (Complex I) that is believed to belong to CC the minimal assembly required for catalysis. Complex I functions CC in the transfer of electrons from NADH to the respiratory chain. CC The immediate electron acceptor for the enzyme is believed to be CC ubiquinone (By similarity). CC -!- CATALYTIC ACTIVITY: NADH + ubiquinone = NAD(+) + ubiquinol. CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass CC membrane protein (By similarity). CC -!- SIMILARITY: Belongs to the complex I subunit 2 family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JQ411917; AFJ06483.1; -; Genomic_DNA. DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. DR GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:EC. DR GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IEA:InterPro. DR InterPro; IPR010933; NADH_DH_su2_C. DR InterPro; IPR001750; NADH_UbQ/plastoQ_OxRdtase. DR InterPro; IPR003917; NADH_UbQ_OxRdtase_chain2. DR Pfam; PF06444; NADH_dehy_S2_C; 1. DR Pfam; PF00361; Oxidored_q1; 1. DR PRINTS; PR01436; NADHDHGNASE2. PE 3: Inferred from homology; KW Electron transport; Membrane; Mitochondrion; KW Mitochondrion inner membrane; NAD; Oxidoreductase; Respiratory chain; KW Transmembrane; Transmembrane helix; Transport; Ubiquinone. FT NON_TER 1 1 FT NON_TER 323 323 SQ SEQUENCE 323 AA; 36309 MW; BE62BC4D0B42734C CRC64; ITGTTLVLIA SHWMFMWVGL ELSMLAMIPL MTYSNNPRST EAATKYFLTQ ATASMILLLA ILNNTSNSGQ WNIIQPEDML SQYLFLVALG MKLGLAPFHF WVPEVTQGIP IKSGLILLTW QKLAPISIMY QLSPYLNKNM MITMALMSIL MGGWGGLNQM QTRKIMAYSS IAHMGWMSAI VTYNPPMMML NLFIYIALTM TMFLALNHLS AKSTSTLSMA WNTNATLTSI LLITLMSLGG LPPLTGFLPK WVIIQELISN HNILVSLIMA MAALLNLYFY LRLTYNSALT LFPTPNNMKF SWRMNKQKSV WPISPLLMMS CMS //