ID I1E3U9_9NEOB Unreviewed; 241 AA. AC I1E3U9; DT 13-JUN-2012, integrated into UniProtKB/TrEMBL. DT 13-JUN-2012, sequence version 1. DT 05-SEP-2012, entry version 3. DE RecName: Full=Cytochrome c oxidase subunit 1; DE EC=1.9.3.1; DE Flags: Fragment; GN Name=COI; OS Rana daunchina (Emei music frog). OG Mitochondrion. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana; OC Nidirana. OX NCBI_TaxID=877584; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=22448286; DOI=10.1371/journal.pone.0034013; RA Li Z., Yu G., Rao D., Yang J.; RT "Phylogeography and Demographic History of Babina pleuraden (Anura, RT Ranidae) in Southwestern China."; RL PLoS ONE 7:E34013-E34013(2012). CC -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory CC chain that catalyzes the reduction of oxygen to water. Subunits 1- CC 3 form the functional core of the enzyme complex. CO I is the CC catalytic subunit of the enzyme. Electrons originating in CC cytochrome c are transferred via the copper A center of subunit 2 CC and heme A of subunit 1 to the bimetallic center formed by heme A3 CC and copper B (By similarity). CC -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4 CC ferricytochrome c + 2 H(2)O. CC -!- PATHWAY: Energy metabolism; oxidative phosphorylation. CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass CC membrane protein (By similarity). CC -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; HQ395353; ADW27358.1; -; Genomic_DNA. DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW. PE 3: Inferred from homology; KW Copper; Electron transport; Heme; Iron; Membrane; Metal-binding; KW Mitochondrion; Mitochondrion inner membrane; Oxidoreductase; KW Respiratory chain; Transmembrane; Transport. FT NON_TER 1 1 FT NON_TER 241 241 SQ SEQUENCE 241 AA; 26128 MW; E4E031D59BD35853 CRC64; MVGTALSLLI RAELSQPGAL LGDDQIYNVI VTAHAFVMIF FMVMPILIGG FGNWLVPLMI GAPDMAFPRM NNMSFWLLPP SFFLLLASST VEAGVGTGWT VYPPLAGNLA HAGPSVDLAI FSLHLAGVSS ILGAINFITT IINMKPPSTT QYQTPLFVWS VLITAVLLLL SLPVLAAGIT MLLTDRNLNT TFFDPAGGGD PILYQHLFWF FGHPEVYILI LPGFGIISHV VAYYSNKKEP F //