ID I0BRS6_9BACL Unreviewed; 196 AA. AC I0BRS6; DT 13-JUN-2012, integrated into UniProtKB/TrEMBL. DT 13-JUN-2012, sequence version 1. DT 05-SEP-2012, entry version 3. DE RecName: Full=ATP-dependent Clp protease proteolytic subunit 3; DE EC=3.4.21.92; DE AltName: Full=Endopeptidase Clp 3; GN Name=clpP3; ORFNames=B2K_30945; OS Paenibacillus mucilaginosus K02. OC Bacteria; Firmicutes; Bacillales; Paenibacillaceae; Paenibacillus. OX NCBI_TaxID=997761; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=K02; RA Xiao B., Sun L., Xiao L., Lian B.; RT "Complete genome sequence of Paenibacillus mucilaginosus K02."; RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Cleaves peptides in various proteins in a process that CC requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a CC major role in the degradation of misfolded proteins (By CC similarity). CC -!- CATALYTIC ACTIVITY: Hydrolysis of proteins to small peptides in CC the presence of ATP and magnesium. Alpha-casein is the usual test CC substrate. In the absence of ATP, only oligopeptides shorter than CC five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec; CC and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage of the -Tyr-|-Leu- CC and -Tyr-|-Trp bonds also occurs). CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). CC -!- SIMILARITY: Belongs to the peptidase S14 family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP003422; AFH65073.1; -; Genomic_DNA. DR RefSeq; YP_006192838.1; NC_017672.1. DR GeneID; 12734302; -. PE 3: Inferred from homology; KW ATP-binding; Cytoplasm; Hydrolase; Nucleotide-binding; Protease; KW Serine protease. FT ACT_SITE 98 98 By similarity. FT ACT_SITE 123 123 By similarity. SQ SEQUENCE 196 AA; 21462 MW; 9AFA59087989C59A CRC64; MTLVPMVVEQ EGRGERSYDI YSRLLKDRII FLGSAIDDDV ANLVIAQLLF LAATDPDKDI HLYINSPGGS VTAGMGIYDT MQFIKPDVST ICVGLAASMG SLLLTAGAPG KRFALPNSEV MIHQPLGGVR GQASDIKIHA DWIIKTKRKL NEIYVARTGQ PYDKIERDTD RDNFMSAAEA KEYGLIDAVI TRSDLT //