ID H8ZEK1_NEMS1 Unreviewed; 447 AA. AC H8ZEK1; DT 16-MAY-2012, integrated into UniProtKB/TrEMBL. DT 16-MAY-2012, sequence version 1. DT 13-NOV-2019, entry version 23. DE RecName: Full=Na_H_Exchanger domain-containing protein {ECO:0000259|Pfam:PF00999}; GN ORFNames=NERG_02022 {ECO:0000313|EMBL:EHY64966.1}; OS Nematocida sp. 1 (strain ERTm2 / ATCC PRA-371) (Nematode killer OS fungus). OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Nematocida; OC unclassified Nematocida. OX NCBI_TaxID=944018 {ECO:0000313|EMBL:EHY64966.1, ECO:0000313|Proteomes:UP000005622}; RN [1] {ECO:0000313|Proteomes:UP000005622} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ERTm2 {ECO:0000313|Proteomes:UP000005622}; RX PubMed=22813931; DOI=10.1101/gr.142802.112; RA Cuomo C.A., Desjardins C.A., Bakowski M.A., Goldberg J., Ma A.T., RA Becnel J.J., Didier E.S., Fan L., Heiman D.I., Levin J.Z., Young S., RA Zeng Q., Troemel E.R.; RT "Microsporidian genome analysis reveals evolutionary strategies for RT obligate intracellular growth."; RL Genome Res. 0:0-0(2012). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JH604637; EHY64966.1; -; Genomic_DNA. DR EnsemblFungi; EHY64966; EHY64966; NERG_02022. DR Proteomes; UP000005622; Unassembled WGS sequence. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0015299; F:solute:proton antiporter activity; IEA:InterPro. DR InterPro; IPR006153; Cation/H_exchanger. DR Pfam; PF00999; Na_H_Exchanger; 1. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000005622}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000005622}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 29 48 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 69 90 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 96 120 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 161 183 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 203 228 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 240 259 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 352 370 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 390 413 Helical. {ECO:0000256|SAM:Phobius}. FT DOMAIN 11 409 Na_H_Exchanger. {ECO:0000259|Pfam: FT PF00999}. SQ SEQUENCE 447 AA; 50047 MW; 145518FC64EA36E6 CRC64; MQSFALCCSI LGGFILSFGL ISLFIKERLY IAETTVATLY GIICALICKD QKDTLPVESL KNTQFMFHFS HIVLSLQLVA VGVTVPKIFM KKNWKPLMVL LLPVMMIMYA VSSTIIKYVF SMDWLPAMMI GACITPTDPV LASAVIKGKF ANKYIPSRLR YLLAVESGAN DGLGFPLLVL PILLMQFKDS TEPVAGALRK WCIHTWGFEI LFAIVIGAVI GALARILLKY SVKKMLIDKE SFLAYSLALA ILVTGITAKM ESDDLLAVFV SGLFFAWDEE MVMDMKNSHV MEVVDLLFNQ SFFIVLGIIL PLDVLGWKSM LASVLILVFR RMPALLLMQL CGFLPEFTTR EILFAGWFGP IGVGAIFFAY HSMHELNSID KELADSVLEI VQAIVFSSIV VHGTTAPIIH MHLRRKQKKH KKTVINIYES DTEIERDNEN AQLQEII //