ID   H6U2A7_9DINO            Unreviewed;       352 AA.
AC   H6U2A7;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   14-MAY-2014, entry version 13.
DE   RecName: Full=Cytochrome c oxidase subunit 1;
DE            EC=1.9.3.1;
DE   Flags: Fragment;
GN   Name=COI;
OS   Symbiodinium sp. C1.
OG   Mitochondrion.
OC   Eukaryota; Alveolata; Dinophyceae; Suessiales; Symbiodiniaceae;
OC   Symbiodinium; Symbiodinium sp. clade C.
OX   NCBI_TaxID=293213;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=22238660; DOI=10.1371/journal.pone.0029816;
RA   Pochon X., Putnam H.M., Burki F., Gates R.D.;
RT   "Identifying and characterizing alternative molecular markers for the
RT   symbiotic and free-living dinoflagellate genus Symbiodinium.";
RL   PLoS ONE 7:E29816-E29816(2012).
CC   -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory
CC       chain that catalyzes the reduction of oxygen to water. Subunits 1-
CC       3 form the functional core of the enzyme complex. CO I is the
CC       catalytic subunit of the enzyme. Electrons originating in
CC       cytochrome c are transferred via the copper A center of subunit 2
CC       and heme A of subunit 1 to the bimetallic center formed by heme A3
CC       and copper B (By similarity).
CC   -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4
CC       ferricytochrome c + 2 H(2)O.
CC   -!- PATHWAY: Energy metabolism; oxidative phosphorylation.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass
CC       membrane protein (By similarity).
CC   -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family.
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DR   EMBL; JN557891; AEM91560.1; -; Genomic_DNA.
DR   UniPathway; UPA00705; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0009060; P:aerobic respiration; IEA:InterPro.
DR   GO; GO:0006119; P:oxidative phosphorylation; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.20.210.10; -; 1.
DR   InterPro; IPR000883; Cyt_c_Oxase_su1.
DR   InterPro; IPR023615; Cyt_c_Oxase_su1_BS.
DR   InterPro; IPR023616; Cyt_c_Oxase_su1_dom.
DR   PANTHER; PTHR10422; PTHR10422; 1.
DR   Pfam; PF00115; COX1; 1.
DR   PRINTS; PR01165; CYCOXIDASEI.
DR   SUPFAM; SSF81442; SSF81442; 1.
DR   PROSITE; PS50855; COX1; 1.
DR   PROSITE; PS00077; COX1_CUB; 1.
PE   3: Inferred from homology;
KW   Copper; Electron transport; Heme; Iron; Membrane; Metal-binding;
KW   Mitochondrion; Mitochondrion inner membrane; Oxidoreductase;
KW   Respiratory chain; Transmembrane; Transport.
FT   NON_TER       1      1
FT   NON_TER     352    352
SQ   SEQUENCE   352 AA;  39084 MW;  5480C0B15C64FA36 CRC64;
     SGTLISVLIR IELYSSGNRI ISPENQNFYN ISITLHGFLM IFFLVMPGLF GGFGNYFVPI
     FQGSPEVVYP RVNNFSILIL LLSYLFLILS LISEFGGGTG WTLYPPLSTS FMTLSPSSTG
     NLIFGLIISG ISSCLTSLNF WTTIHFLRSY YLILSSIPLF PWAFLITAFM LLLTLPILSG
     TLLLILGDLH SNTLFFDPIF GGDPIFYQHL FWFFGHPEVY ILIIPAFGII SIIISGILQL
     IIFANQSMIF AMSSISLLGG LVWGHHMYTV GLESDTRAYF TGVTILISLP TGTKIFNWLF
     TYLSNPPLLH LRITSVFLSH LFLLMFTIGG STGIILGNGA VDLGLHDTYY VV
//