ID H3K2X4_9EURO Unreviewed; 415 AA. AC H3K2X4; DT 18-APR-2012, integrated into UniProtKB/TrEMBL. DT 18-APR-2012, sequence version 1. DT 31-JUL-2019, entry version 23. DE SubName: Full=Squalene epoxidase {ECO:0000313|EMBL:BAL48859.1}; GN Name=erg1 {ECO:0000313|EMBL:BAL48859.1}; OS Trichophyton mentagrophytes. OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton. OX NCBI_TaxID=523103 {ECO:0000313|EMBL:BAL48859.1}; RN [1] {ECO:0000313|EMBL:BAL48859.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=TIMM2789 {ECO:0000313|EMBL:BAL48859.1}; RX PubMed=22610431; DOI=10.1128/AEM.00464-12; RA Iwata A., Alshahni M.M., Nishiyama Y., Makimura K., Abe S., Yamada T.; RT "Development of a tightly regulatable copper-mediated gene switch RT system in dermatophytes."; RL Appl. Environ. Microbiol. 78:5204-5211(2012). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB690298; BAL48859.1; -; Genomic_DNA. DR GO; GO:0016021; C:integral component of membrane; IEA:InterPro. DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. DR GO; GO:0004506; F:squalene monooxygenase activity; IEA:InterPro. DR GO; GO:0016126; P:sterol biosynthetic process; IEA:InterPro. DR Gene3D; 3.50.50.60; -; 1. DR InterPro; IPR003953; FAD-binding_2. DR InterPro; IPR036188; FAD/NAD-bd_sf. DR InterPro; IPR013698; Squalene_epoxidase. DR InterPro; IPR040125; Squalene_monox. DR PANTHER; PTHR10835; PTHR10835; 1. DR Pfam; PF00890; FAD_binding_2; 1. DR Pfam; PF08491; SE; 1. DR SUPFAM; SSF51905; SSF51905; 1. PE 4: Predicted; FT DOMAIN 40 69 FAD_binding_2. {ECO:0000259|Pfam: FT PF00890}. FT DOMAIN 191 404 SE. {ECO:0000259|Pfam:PF08491}. FT REGION 1 31 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. SQ SEQUENCE 415 AA; 45166 MW; D455371447E391B4 CRC64; MVVEAPPCPQ SGNGFANGSA KPKAYRDEAE RRRYEHHEAD VVIIGAGIAG CALAVALGNQ GRSVILLERS LKEPDRIVGE LLQPGGVRAL EQLGLRDCLE GIDAVRTYGY DVIYFGNGVK IPFPSDANDK ILEGRCFHHG RFIMRLREAA AANPNVTIVE TKAVSTIKST HTGDVLGVQC QTDGKQDFYF GPLTVVADGY ASTFRKEYLP IQPVAKSKFW GLELIDAKLP IPGHGHVVLG DFPPILIYQI GEHETRILID IPDNLPSASV ANGGVKGHMR NVVLPSLPEC IRPSFEAALE KGGFRSMPNS FLRPVTNRIP GLMFLGDSLN MRHPLTGGGM TVAFNDVVLL RNLLSPEAVP DLSDTKLVLK QLSKFHWQRK SLISVINILA QSLYSIFAAG GKHMFSLPLL LVSGY //