ID H3BPE3_HUMAN Unreviewed; 132 AA. AC H3BPE3; DT 18-APR-2012, integrated into UniProtKB/TrEMBL. DT 05-OCT-2016, sequence version 8. DT 08-MAY-2019, entry version 46. DE SubName: Full=Eukaryotic translation initiation factor 3 subunit C {ECO:0000313|Ensembl:ENSP00000455277}; DE Flags: Fragment; GN Name=EIF3C {ECO:0000313|Ensembl:ENSP00000455277}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000455277, ECO:0000313|Proteomes:UP000005640}; RN [1] {ECO:0000313|Ensembl:ENSP00000455277, ECO:0000313|Proteomes:UP000005640} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=15616553; DOI=10.1038/nature03187; RA Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., RA Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., RA Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J., RA Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L., RA Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A., RA Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D., RA Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J., RA Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M., RA Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I., RA Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W., RA Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A., RA Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S., RA Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J., RA Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D., RA Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., RA Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., RA Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L., RA Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., RA Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M., RA Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L., RA Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D., RA Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P., RA Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M., RA Rubin E.M., Pennacchio L.A.; RT "The sequence and analysis of duplication-rich human chromosome 16."; RL Nature 432:988-994(2004). RN [2] {ECO:0000313|Ensembl:ENSP00000455277} RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC145285; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR jPOST; H3BPE3; -. DR PeptideAtlas; H3BPE3; -. DR PRIDE; H3BPE3; -. DR Ensembl; ENST00000568426; ENSP00000455277; ENSG00000184110. DR UCSC; uc059son.1; human. DR HGNC; HGNC:3279; EIF3C. DR OpenTargets; ENSG00000184110; -. DR eggNOG; KOG1076; Eukaryota. DR eggNOG; ENOG410XRU3; LUCA. DR GeneTree; ENSGT00390000017900; -. DR ChiTaRS; EIF3C; human. DR Proteomes; UP000005640; Chromosome 16. DR Bgee; ENSG00000184110; Expressed in 167 organ(s), highest expression level in right testis. DR ExpressionAtlas; H3BPE3; baseline and differential. DR GO; GO:0005852; C:eukaryotic translation initiation factor 3 complex; IEA:InterPro. DR GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro. DR GO; GO:0031369; F:translation initiation factor binding; IEA:InterPro. DR InterPro; IPR027516; EIF3C. DR InterPro; IPR008905; EIF3C_N_dom. DR PANTHER; PTHR13937; PTHR13937; 1. DR Pfam; PF05470; eIF-3c_N; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000005640}; KW Proteomics identification {ECO:0000213|PeptideAtlas:H3BPE3}; KW Reference proteome {ECO:0000313|Proteomes:UP000005640}. FT DOMAIN 1 131 eIF-3c_N. {ECO:0000259|Pfam:PF05470}. FT NON_TER 132 132 {ECO:0000313|Ensembl:ENSP00000455277}. SQ SEQUENCE 132 AA; 15275 MW; FA8E12D2EFCD1758 CRC64; MKIRDVTKCL EEFELLGKAY GKAKSIVDKE GVPRFYIRIL ADLEDYLNEL WEDKEGKKKM NKNNAKALST LRQKIRKYNR DFESHITSYK QNPEQSADED AEKNEEDSEG SSDEDEDEDG VSAATFLKKK SE //