ID   H2Q4W0_PANTR            Unreviewed;       171 AA.
AC   H2Q4W0; A0A2J8N2P6;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   05-DEC-2018, entry version 37.
DE   SubName: Full=CD3D isoform 1 {ECO:0000313|EMBL:PNI66040.1};
DE   SubName: Full=CD3d molecule {ECO:0000313|Ensembl:ENSPTRP00000007442};
GN   Name=CD3D {ECO:0000313|Ensembl:ENSPTRP00000007442,
GN   ECO:0000313|VGNC:VGNC:6481};
GN   ORFNames=CK820_G0015735 {ECO:0000313|EMBL:PNI66040.1};
OS   Pan troglodytes (Chimpanzee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Pan.
OX   NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000007442, ECO:0000313|Proteomes:UP000002277};
RN   [1] {ECO:0000313|Ensembl:ENSPTRP00000007442, ECO:0000313|Proteomes:UP000002277}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16136131; DOI=10.1038/nature04072;
RG   Chimpanzee sequencing and analysis consortium;
RT   "Initial sequence of the chimpanzee genome and comparison with the
RT   human genome.";
RL   Nature 437:69-87(2005).
RN   [2] {ECO:0000313|Ensembl:ENSPTRP00000007442}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [3] {ECO:0000313|EMBL:PNI66040.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Yerkes chimp pedigree #C0471 {ECO:0000313|EMBL:PNI66040.1};
RC   TISSUE=Blood {ECO:0000313|EMBL:PNI66040.1};
RA   Pollen A., Hastie A., Hormozdiari F., Dougherty M., Liu R.,
RA   Chaisson M., Hoppe E., Hill C., Pang A., Hillier L., Baker C.,
RA   Armstrong J., Shendure J., Paten B., Wilson R., Chao H., Schneider V.,
RA   Ventura M., Kronenberg Z., Murali S., Gordon D., Cantsilieris S.,
RA   Munson K., Nelson B., Raja A., Underwood J., Diekhans M., Fiddes I.,
RA   Haussler D., Eichler E.;
RT   "High-resolution comparative analysis of great ape genomes.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AACZ04006748; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; NBAG03000239; PNI66040.1; -; Genomic_DNA.
DR   RefSeq; XP_508789.2; XM_508789.6.
DR   STRING; 9598.ENSPTRP00000007442; -.
DR   PaxDb; H2Q4W0; -.
DR   Ensembl; ENSPTRT00000008062; ENSPTRP00000007442; ENSPTRG00000004339.
DR   GeneID; 451584; -.
DR   CTD; 915; -.
DR   VGNC; VGNC:6481; CD3D.
DR   eggNOG; ENOG410IWAX; Eukaryota.
DR   eggNOG; ENOG410Y2TD; LUCA.
DR   GeneTree; ENSGT00940000153312; -.
DR   InParanoid; H2Q4W0; -.
DR   OMA; GENWPRK; -.
DR   OrthoDB; EOG091G0U7X; -.
DR   TreeFam; TF335892; -.
DR   Proteomes; UP000002277; Chromosome 11.
DR   Bgee; ENSPTRG00000004339; Expressed in 5 organ(s), highest expression level in adult mammalian kidney.
DR   GO; GO:0042105; C:alpha-beta T cell receptor complex; IBA:GO_Central.
DR   GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IBA:GO_Central.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IBA:GO_Central.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR   GO; GO:0045059; P:positive thymic T cell selection; IBA:GO_Central.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0030217; P:T cell differentiation; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR015484; CD3_esu/gsu/dsu.
DR   InterPro; IPR015485; CD3D.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR032052; Ig_4.
DR   InterPro; IPR003110; Phos_immunorcpt_sig_ITAM.
DR   PANTHER; PTHR10570; PTHR10570; 1.
DR   PANTHER; PTHR10570:SF5; PTHR10570:SF5; 1.
DR   Pfam; PF16680; Ig_4; 1.
DR   Pfam; PF02189; ITAM; 1.
DR   SMART; SM00077; ITAM; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS51055; ITAM_1; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002277};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22    171       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5015092440.
FT   DOMAIN       30    104       Ig_4. {ECO:0000259|Pfam:PF16680}.
SQ   SEQUENCE   171 AA;  18951 MW;  DAAE3C4CB2862B3D CRC64;
     MEHSTFLSGL VLATLLSQVS PFKIPIEELE DRVFVNCNTS VTWVEGTVGT LLSDITRLDL
     GKRILDPRGI YRCNGTDTYK DKESTVQVHY RMCQSCVELD PATVAGIIVT DVIATLLLAL
     GVFCFAGHET GRLSGAADTQ ALLRNDQVYQ PLRDRDDVQY SRLGGNWARN K
//