ID H2NDQ0_PONAB Unreviewed; 351 AA. AC H2NDQ0; DT 21-MAR-2012, integrated into UniProtKB/TrEMBL. DT 09-JAN-2013, sequence version 2. DT 02-DEC-2020, entry version 46. DE RecName: Full=CD44 antigen {ECO:0000256|ARBA:ARBA00020474}; DE AltName: Full=Extracellular matrix receptor III {ECO:0000256|ARBA:ARBA00014737}; DE AltName: Full=GP90 lymphocyte homing/adhesion receptor {ECO:0000256|ARBA:ARBA00019064}; DE AltName: Full=HUTCH-I {ECO:0000256|ARBA:ARBA00016379}; DE AltName: Full=Hermes antigen {ECO:0000256|ARBA:ARBA00020676}; DE AltName: Full=Hyaluronate receptor {ECO:0000256|ARBA:ARBA00021652}; DE AltName: Full=Phagocytic glycoprotein 1 {ECO:0000256|ARBA:ARBA00022123}; DE AltName: Full=Phagocytic glycoprotein I {ECO:0000256|ARBA:ARBA00022139}; OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Pongo. OX NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000003856, ECO:0000313|Proteomes:UP000001595}; RN [1] {ECO:0000313|Ensembl:ENSPPYP00000003856, ECO:0000313|Proteomes:UP000001595} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Wilson R.K., Mardis E.; RT "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome."; RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Ensembl:ENSPPYP00000003856} RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Cell projection, microvillus CC {ECO:0000256|ARBA:ARBA00004105}. CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00323}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR STRING; 9601.ENSPPYP00000003856; -. DR Ensembl; ENSPPYT00000004004; ENSPPYP00000003856; ENSPPYG00000003358. DR eggNOG; ENOG502RX7Q; Eukaryota. DR GeneTree; ENSGT00530000063822; -. DR HOGENOM; CLU_056870_0_0_1; -. DR InParanoid; H2NDQ0; -. DR OMA; RIPATNM; -. DR TreeFam; TF334173; -. DR Proteomes; UP000001595; Chromosome 11. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005902; C:microvillus; IEA:UniProtKB-SubCell. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0005540; F:hyaluronic acid binding; IEA:InterPro. DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. DR Gene3D; 3.10.100.10; -; 1. DR InterPro; IPR016186; C-type_lectin-like/link_sf. DR InterPro; IPR001231; CD44_antigen. DR InterPro; IPR043210; CD44_antigen-like. DR InterPro; IPR016187; CTDL_fold. DR InterPro; IPR000538; Link_dom. DR PANTHER; PTHR10225; PTHR10225; 2. DR PANTHER; PTHR10225:SF6; PTHR10225:SF6; 2. DR Pfam; PF00193; Xlink; 1. DR PRINTS; PR00658; CD44. DR PRINTS; PR01265; LINKMODULE. DR SMART; SM00445; LINK; 1. DR SUPFAM; SSF56436; SSF56436; 1. DR PROSITE; PS01241; LINK_1; 1. DR PROSITE; PS50963; LINK_2; 1. PE 4: Predicted; KW Cell projection {ECO:0000256|ARBA:ARBA00023273}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}; KW Reference proteome {ECO:0000313|Proteomes:UP000001595}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 259..280 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 22..110 FT /note="Link" FT /evidence="ECO:0000259|PROSITE:PS50963" FT REGION 146..179 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 196..251 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 157..179 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 219..251 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 351 AA; 38255 MW; CA512B260800EE72 CRC64; MQKNLTFLFL PIDLNITCRF AGVFHVEKNG RYSISRTEAA DLCKAFNSTL PTMAQMEKAL SIGFETCRYG FIEGHVVIPR IHPNSICAAN NTGVYILTSN TSQYDTYCFN ASAPPEEDCT SVTDLPNAFD GPITITIVNR DGTRYVQKGE YRTNPEDIYP SNPTDDDVSS GSSSERSSTS GGYIFYTFST VHPIPDEDGP WITDSTDRTP ATRDQDAFRP SGGSHTTHGS ESAGHSHGSQ EGGENTTSGP IRTPQIPEWL IILASLLALA LILAVCIAVN SRRRCGQKKK LVINSGNGAV EDRKPSGLNG EASKSQEMVH LVNKESSETP DQFMTADETR NLQNVDMKIG V //