ID H2NDQ0_PONAB Unreviewed; 351 AA. AC H2NDQ0; DT 21-MAR-2012, integrated into UniProtKB/TrEMBL. DT 09-JAN-2013, sequence version 2. DT 30-NOV-2016, entry version 29. DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000003856}; OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Pongo. OX NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000003856, ECO:0000313|Proteomes:UP000001595}; RN [1] {ECO:0000313|Ensembl:ENSPPYP00000003856, ECO:0000313|Proteomes:UP000001595} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Wilson R.K., Mardis E.; RT "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome."; RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Ensembl:ENSPPYP00000003856} RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSPPYP00000003856}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; ABGA01192243; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; ABGA01192244; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; ABGA01192245; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR STRING; 9601.ENSPPYP00000003856; -. DR Ensembl; ENSPPYT00000004004; ENSPPYP00000003856; ENSPPYG00000003358. DR eggNOG; ENOG410IZCP; Eukaryota. DR eggNOG; ENOG4111S6T; LUCA. DR GeneTree; ENSGT00530000063822; -. DR InParanoid; H2NDQ0; -. DR OMA; NISCRYA; -. DR OrthoDB; EOG091G0F98; -. DR TreeFam; TF334173; -. DR Proteomes; UP000001595; Chromosome 11. DR GO; GO:0009986; C:cell surface; IEA:Ensembl. DR GO; GO:0070062; C:extracellular exosome; IEA:Ensembl. DR GO; GO:0005925; C:focal adhesion; IEA:Ensembl. DR GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0035692; C:macrophage migration inhibitory factor receptor complex; IEA:Ensembl. DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl. DR GO; GO:0004896; F:cytokine receptor activity; IEA:Ensembl. DR GO; GO:0005540; F:hyaluronic acid binding; IEA:Ensembl. DR GO; GO:0051216; P:cartilage development; IEA:Ensembl. DR GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; IEA:Ensembl. DR GO; GO:0030214; P:hyaluronan catabolic process; IEA:Ensembl. DR GO; GO:0070487; P:monocyte aggregation; IEA:Ensembl. DR GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl. DR GO; GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IEA:Ensembl. DR GO; GO:1902166; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IEA:Ensembl. DR GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl. DR GO; GO:0034116; P:positive regulation of heterotypic cell-cell adhesion; IEA:Ensembl. DR GO; GO:1900625; P:positive regulation of monocyte aggregation; IEA:Ensembl. DR GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IEA:Ensembl. DR GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl. DR Gene3D; 3.10.100.10; -; 1. DR InterPro; IPR016186; C-type_lectin-like/link. DR InterPro; IPR001231; CD44_antigen. DR InterPro; IPR016187; CTDL_fold. DR InterPro; IPR000538; Link_dom. DR Pfam; PF00193; Xlink; 1. DR PRINTS; PR00658; CD44. DR PRINTS; PR01265; LINKMODULE. DR SMART; SM00445; LINK; 1. DR SUPFAM; SSF56436; SSF56436; 1. DR PROSITE; PS01241; LINK_1; 1. DR PROSITE; PS50963; LINK_2; 1. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000001595}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000001595}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 259 280 Helical. {ECO:0000256|SAM:Phobius}. FT DOMAIN 22 110 Link. {ECO:0000259|PROSITE:PS50963}. SQ SEQUENCE 351 AA; 38255 MW; CA512B260800EE72 CRC64; MQKNLTFLFL PIDLNITCRF AGVFHVEKNG RYSISRTEAA DLCKAFNSTL PTMAQMEKAL SIGFETCRYG FIEGHVVIPR IHPNSICAAN NTGVYILTSN TSQYDTYCFN ASAPPEEDCT SVTDLPNAFD GPITITIVNR DGTRYVQKGE YRTNPEDIYP SNPTDDDVSS GSSSERSSTS GGYIFYTFST VHPIPDEDGP WITDSTDRTP ATRDQDAFRP SGGSHTTHGS ESAGHSHGSQ EGGENTTSGP IRTPQIPEWL IILASLLALA LILAVCIAVN SRRRCGQKKK LVINSGNGAV EDRKPSGLNG EASKSQEMVH LVNKESSETP DQFMTADETR NLQNVDMKIG V //