ID H2MWP8_ORYLA Unreviewed; 118 AA. AC H2MWP8; DT 21-MAR-2012, integrated into UniProtKB/TrEMBL. DT 21-MAR-2012, sequence version 1. DT 02-DEC-2020, entry version 38. DE RecName: Full=Galanin {ECO:0000256|ARBA:ARBA00015286}; DE AltName: Full=Galanin message-associated peptide {ECO:0000256|ARBA:ARBA00019720}; DE AltName: Full=Galanin peptides {ECO:0000256|ARBA:ARBA00019079}; GN Name=gal {ECO:0000313|Ensembl:ENSORLP00000023304}; OS Oryzias latipes (Japanese rice fish) (Japanese killifish). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae; OC Oryzias. OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000023304, ECO:0000313|Proteomes:UP000001038}; RN [1] {ECO:0000313|Ensembl:ENSORLP00000023304, ECO:0000313|Proteomes:UP000001038} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000023304, RC ECO:0000313|Proteomes:UP000001038}; RX PubMed=17554307; DOI=10.1038/nature05846; RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T., RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A., RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S., RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S., RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K., RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.; RT "The medaka draft genome and insights into vertebrate genome evolution."; RL Nature 447:714-719(2007). RN [2] {ECO:0000313|Ensembl:ENSORLP00000023304} RP IDENTIFICATION. RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000023304}; RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}. CC -!- SIMILARITY: Belongs to the galanin family. CC {ECO:0000256|ARBA:ARBA00006871}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; XP_004086257.1; XM_004086209.2. DR Ensembl; ENSORLT00000023305; ENSORLP00000023304; ENSORLG00000018643. DR GeneID; 101157924; -. DR KEGG; ola:101157924; -. DR CTD; 100006361; -. DR GeneTree; ENSGT00390000009663; -. DR HOGENOM; CLU_166244_0_0_1; -. DR Proteomes; UP000001038; Chromosome 6. DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. DR GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW. DR InterPro; IPR008174; Galanin. DR InterPro; IPR008175; Galanin_pre. DR InterPro; IPR013068; GMAP. DR PANTHER; PTHR16839; PTHR16839; 1. DR Pfam; PF01296; Galanin; 1. DR Pfam; PF06540; GMAP; 1. DR PRINTS; PR00273; GALANIN. DR SMART; SM00071; Galanin; 1. DR PROSITE; PS00861; GALANIN; 1. PE 3: Inferred from homology; KW Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685}; KW Hormone {ECO:0000256|ARBA:ARBA00022702}; KW Reference proteome {ECO:0000313|Proteomes:UP000001038}; KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1..19 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 20..118 FT /note="Galanin" FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5003566678" FT DOMAIN 33..45 FT /note="GALANIN" FT /evidence="ECO:0000259|PROSITE:PS00861" SQ SEQUENCE 118 AA; 12767 MW; 11B5D641C9C26622 CRC64; MHKCLGILCA SLIFCAALSE SIGLVIAAKE KRGWTLNSAG YLLGPHGIDG HRTLGDKQGL AGKRDMGQEE DFRPGSLRIA DEDIIHTVVD FLSYLKLKEM GALENLPPSV TSDEMTNP //