ID H2L0Q6_CAEEL Unreviewed; 254 AA. AC H2L0Q6; DT 21-MAR-2012, integrated into UniProtKB/TrEMBL. DT 21-MAR-2012, sequence version 1. DT 25-MAY-2022, entry version 80. DE SubName: Full=RAL (Ras-related GTPase) homolog {ECO:0000313|EMBL:CCD73809.1}; GN Name=ral-1 {ECO:0000313|EMBL:CCD73809.1, GN ECO:0000313|WormBase:Y53G8AR.3b}; GN ORFNames=CELE_Y53G8AR.3 {ECO:0000313|EMBL:CCD73809.1}, Y53G8AR.3 GN {ECO:0000313|WormBase:Y53G8AR.3b}; OS Caenorhabditis elegans. OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; OC Caenorhabditis. OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCD73809.1, ECO:0000313|Proteomes:UP000001940}; RN [1] {ECO:0000313|Proteomes:UP000001940} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Bristol N2 {ECO:0000313|Proteomes:UP000001940}; RX PubMed=9851916; DOI=10.1126/science.282.5396.2012; RG The C. elegans sequencing consortium; RA Sulson J.E., Waterston R.; RT "Genome sequence of the nematode C. elegans: a platform for investigating RT biology."; RL Science 282:2012-2018(1998). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BX284603; CCD73809.1; -; Genomic_DNA. DR RefSeq; NP_001254866.1; NM_001267937.1. DR AlphaFoldDB; H2L0Q6; -. DR SMR; H2L0Q6; -. DR IntAct; H2L0Q6; 2. DR STRING; 6239.Y53G8AR.3b; -. DR EPD; H2L0Q6; -. DR PaxDb; H2L0Q6; -. DR PeptideAtlas; H2L0Q6; -. DR EnsemblMetazoa; Y53G8AR.3b.1; Y53G8AR.3b.1; WBGene00021811. DR GeneID; 175433; -. DR KEGG; cel:CELE_Y53G8AR.3; -. DR CTD; 175433; -. DR WormBase; Y53G8AR.3b; CE46416; WBGene00021811; ral-1. DR eggNOG; KOG0395; Eukaryota. DR GeneTree; ENSGT00940000168700; -. DR InParanoid; H2L0Q6; -. DR OMA; WEVSYVE; -. DR OrthoDB; 1259506at2759; -. DR PhylomeDB; H2L0Q6; -. DR Proteomes; UP000001940; Chromosome III. DR Bgee; WBGene00021811; Expressed in pharyngeal muscle cell (C elegans) and 5 other tissues. DR ExpressionAtlas; H2L0Q6; baseline and differential. DR GO; GO:0005886; C:plasma membrane; ISS:WormBase. DR GO; GO:0019003; F:GDP binding; IBA:GO_Central. DR GO; GO:0005525; F:GTP binding; IBA:GO_Central. DR GO; GO:0003924; F:GTPase activity; ISS:WormBase. DR GO; GO:0008340; P:determination of adult lifespan; IMP:WormBase. DR GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; IGI:WormBase. DR GO; GO:0036258; P:multivesicular body assembly; IMP:WormBase. DR GO; GO:0040026; P:positive regulation of vulval development; IGI:WormBase. DR GO; GO:0007265; P:Ras protein signal transduction; IBA:GO_Central. DR GO; GO:0060178; P:regulation of exocyst localization; IMP:WormBase. DR Gene3D; 3.40.50.300; -; 1. DR InterPro; IPR027417; P-loop_NTPase. DR InterPro; IPR005225; Small_GTP-bd_dom. DR InterPro; IPR001806; Small_GTPase. DR InterPro; IPR020849; Small_GTPase_Ras-type. DR PANTHER; PTHR24070; PTHR24070; 1. DR Pfam; PF00071; Ras; 1. DR SMART; SM00174; RHO; 1. DR SUPFAM; SSF52540; SSF52540; 1. DR TIGRFAMs; TIGR00231; small_GTP; 1. DR PROSITE; PS51421; RAS; 1. PE 1: Evidence at protein level; KW GTP-binding {ECO:0000256|ARBA:ARBA00023134}; KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134}; KW Proteomics identification {ECO:0007829|EPD:H2L0Q6, KW ECO:0007829|PeptideAtlas:H2L0Q6}; KW Reference proteome {ECO:0000313|Proteomes:UP000001940}. FT REGION 223..254 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 254 AA; 29073 MW; EFAB584AC838A731 CRC64; MDKVSHVLRN GWNWIKLKFL ALWHFLFRRK SDEPEFYDPE AMASKKASGT LPPQQQVVHK VIMVGTGGVG KSALTLQFMY DEFVEEYEPT KADSYRKKVV LDGEECSIDI LDTAGQEDYS AIRDNYYRSG EGFICVFSIL DMESFEATNE FREQILRVKN SDSSVPIVLV GNKGDMRDQR VVSAELCRQR AEQWGCHYVE TSAKRRENVD KVFYDLMREM KRRKGGSQAQ TGIDASASSG RKKRSGIKKH CTIL //