ID H0YEF9_HUMAN Unreviewed; 387 AA. AC H0YEF9; DT 22-FEB-2012, integrated into UniProtKB/TrEMBL. DT 22-FEB-2012, sequence version 1. DT 31-JAN-2018, entry version 42. DE SubName: Full=Liprin-alpha-1 {ECO:0000313|Ensembl:ENSP00000435752}; DE Flags: Fragment; GN Name=PPFIA1 {ECO:0000313|Ensembl:ENSP00000435752}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000435752, ECO:0000313|Proteomes:UP000005640}; RN [1] {ECO:0000213|PubMed:17081983} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=17081983; DOI=10.1016/j.cell.2006.09.026; RA Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., RA Mann M.; RT "Global, in vivo, and site-specific phosphorylation dynamics in RT signaling networks."; RL Cell 127:635-648(2006). RN [2] {ECO:0000313|Ensembl:ENSP00000435752, ECO:0000313|Proteomes:UP000005640} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=16554811; DOI=10.1038/nature04632; RA Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., RA Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T., RA Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G., RA Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C., RA Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., RA Hattori M., Rogers J., Lander E.S., Sakaki Y.; RT "Human chromosome 11 DNA sequence and analysis including novel gene RT identification."; RL Nature 440:497-500(2006). RN [3] {ECO:0000213|PubMed:18669648} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=18669648; DOI=10.1073/pnas.0805139105; RA Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., RA Elledge S.J., Gygi S.P.; RT "A quantitative atlas of mitotic phosphorylation."; RL Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). RN [4] {ECO:0000213|PubMed:19690332} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=19690332; DOI=10.1126/scisignal.2000007; RA Mayya V., Lundgren D.H., Hwang S.I., Rezaul K., Wu L., Eng J.K., RA Rodionov V., Han D.K.; RT "Quantitative phosphoproteomic analysis of T cell receptor signaling RT reveals system-wide modulation of protein-protein interactions."; RL Sci. Signal. 2:RA46-RA46(2009). RN [5] {ECO:0000213|PubMed:21269460} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21269460; DOI=10.1186/1752-0509-5-17; RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., RA Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.; RT "Initial characterization of the human central proteome."; RL BMC Syst. Biol. 5:17-17(2011). RN [6] {ECO:0000213|PubMed:21406692} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21406692; DOI=10.1126/scisignal.2001570; RA Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., RA Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., RA Blagoev B.; RT "System-wide temporal characterization of the proteome and RT phosphoproteome of human embryonic stem cell differentiation."; RL Sci. Signal. 4:RS3-RS3(2011). RN [7] {ECO:0000313|Ensembl:ENSP00000435752} RP IDENTIFICATION. RG Ensembl; RL Submitted (JAN-2012) to UniProtKB. RN [8] {ECO:0000213|PubMed:23186163} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=23186163; RA Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., RA Mohammed S.; RT "Toward a comprehensive characterization of a human cancer cell RT phosphoproteome."; RL J. Proteome Res. 12:260-271(2013). RN [9] {ECO:0000213|PubMed:24275569} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014; RA Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., RA Wang L., Ye M., Zou H.; RT "An enzyme assisted RP-RPLC approach for in-depth analysis of human RT liver phosphoproteome."; RL J. Proteomics 96:253-262(2014). CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSP00000435752}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AP000487; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AP002336; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; KC877433; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR ProteinModelPortal; H0YEF9; -. DR EPD; H0YEF9; -. DR MaxQB; H0YEF9; -. DR PeptideAtlas; H0YEF9; -. DR PRIDE; H0YEF9; -. DR Ensembl; ENST00000526262; ENSP00000435752; ENSG00000131626. DR UCSC; uc058esd.1; human. DR EuPathDB; HostDB:ENSG00000131626.15; -. DR HGNC; HGNC:9245; PPFIA1. DR OpenTargets; ENSG00000131626; -. DR GeneTree; ENSGT00760000119138; -. DR ChiTaRS; PPFIA1; human. DR Proteomes; UP000005640; Chromosome 11. DR Bgee; ENSG00000131626; -. DR ExpressionAtlas; H0YEF9; baseline and differential. DR InterPro; IPR029515; Liprin. DR InterPro; IPR030438; PPFIA1. DR PANTHER; PTHR12587; PTHR12587; 1. DR PANTHER; PTHR12587:SF15; PTHR12587:SF15; 1. PE 1: Evidence at protein level; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000005640}; KW Proteomics identification {ECO:0000213|EPD:H0YEF9, KW ECO:0000213|MaxQB:H0YEF9, ECO:0000213|PeptideAtlas:H0YEF9}; KW Reference proteome {ECO:0000313|Proteomes:UP000005640}. FT COILED 37 106 {ECO:0000256|SAM:Coils}. FT COILED 110 159 {ECO:0000256|SAM:Coils}. FT COILED 184 239 {ECO:0000256|SAM:Coils}. FT COILED 265 313 {ECO:0000256|SAM:Coils}. FT NON_TER 1 1 {ECO:0000313|Ensembl:ENSP00000435752}. SQ SEQUENCE 387 AA; 44562 MW; 30FCF85F28036936 CRC64; XPSTSGKRSS DGSLSHEEDL AKVIELQEII SKQSREQSQM KERLASLSSH VTELEEDLDT ARKDLIKSEE MNTKLQRDVR EAMAQKEDME ERITTLEKRY LAAQREATSV HDLNDKLENE IANKDSMHRQ TEDKNRQLQE RLELAEQKLQ QTLRKAETLP EVEAELAQRV AALSKSDLLS SGSSAAKEAK LLELTSKLRK AEERHGNIEE RLRQMEAQLE EKNQELQRAR QREKMNEEHN KRLSDTVDKL LSESNERLQL HLKERMAALE DKNSLLREVE SAKKQLEETQ HDKDQLVLNI EALRAELDHM RLRGASLHHG RPHLGSVPDF RFPMADGHTD SYSTSAVLRR PQKGRLAALR DEPSKARYKL LMSRIGNVPS KLVSWQM //