ID G9M5W5_MOUSE Unreviewed; 288 AA. AC G9M5W5; DT 22-FEB-2012, integrated into UniProtKB/TrEMBL. DT 22-FEB-2012, sequence version 1. DT 16-SEP-2015, entry version 17. DE SubName: Full=Forkhead box E3 {ECO:0000313|EMBL:BAL15371.1}; GN Name=Foxe3 {ECO:0000313|EMBL:BAL15371.1, ECO:0000313|MGI:MGI:1353569}; OS Mus musculus domesticus (western European house mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10092 {ECO:0000313|EMBL:BAL15371.1}; RN [1] {ECO:0000313|EMBL:BAL15371.1} RP NUCLEOTIDE SEQUENCE. RA Wada K., Maeda Y.Y., Watanabe K., Oshio T., Ueda T., Takahashi G., RA Yokohama M., Saito J., Seki Y., Takahama S., Ishii R., Shitara H., RA Taya C., Yonekawa H., Kikkawa Y.; RT "A deletion in a cis element of Foxe3 causes cataracts and RT microphthalmia in rct mice."; RL Mamm. Genome 22:693-702(2012). CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|SAAS:SAAS00112314}. CC -!- SIMILARITY: Contains fork-head DNA-binding domain. CC {ECO:0000256|SAAS:SAAS00112367}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB601886; BAL15371.1; -; mRNA. DR UniGene; Mm.377122; -. DR MGI; MGI:1353569; Foxe3. DR GO; GO:0005634; C:nucleus; IBA:GO_Central. DR GO; GO:0005667; C:transcription factor complex; ISO:MGI. DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro. DR GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:GO_Central. DR GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISO:MGI. DR GO; GO:0009653; P:anatomical structure morphogenesis; IBA:GO_Central. DR GO; GO:0043010; P:camera-type eye development; IMP:MGI. DR GO; GO:0048468; P:cell development; IMP:MGI. DR GO; GO:0030154; P:cell differentiation; IBA:GO_Central. DR GO; GO:0001654; P:eye development; IMP:MGI. DR GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IMP:MGI. DR GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GO_Central. DR GO; GO:0006366; P:transcription from RNA polymerase II promoter; ISO:MGI. DR Gene3D; 1.10.10.10; -; 1. DR InterPro; IPR001766; Fork_head_dom. DR InterPro; IPR018122; TF_fork_head_CS_1. DR InterPro; IPR011991; WHTH_DNA-bd_dom. DR Pfam; PF00250; Forkhead; 1. DR PRINTS; PR00053; FORKHEAD. DR SMART; SM00339; FH; 1. DR PROSITE; PS00657; FORK_HEAD_1; 1. DR PROSITE; PS50039; FORK_HEAD_3; 1. PE 2: Evidence at transcript level; KW DNA-binding {ECO:0000256|SAAS:SAAS00112326}; KW Nucleus {ECO:0000256|SAAS:SAAS00112348}; KW Transcription {ECO:0000256|SAAS:SAAS00112360}; KW Transcription regulation {ECO:0000256|SAAS:SAAS00112340}. SQ SEQUENCE 288 AA; 30542 MW; 1642593AEE25A6C5 CRC64; MDAQVAFSGF PALPSLTPSG PQLPTLAGAE PGREPEEVVG GGDAEPTAVP GPGKRRRRPL QRGKPPYSYI ALIAMALAHA PGRRLTLAAI YRFITERFAF YRDSPRKWQN SIRHNLTLND CFVKVPREPG NPGKGNYWTL DPAAADMFDN GSFLRRRKRF KRAELPAPPP PPPPFPYAPF PPPPAPASAP PARLFRLDSL LGLQPEPPGP VAPEPPCCAA PDAAFPPCAA AASPPLYSPA SERLGLPAPL PAEPLLALAG SAGALGPLGA GEAYLRQPGF APGLERYL //