ID G9B2U3_CHLAR Unreviewed; 229 AA. AC G9B2U3; DT 22-FEB-2012, integrated into UniProtKB/TrEMBL. DT 22-FEB-2012, sequence version 1. DT 18-JAN-2017, entry version 26. DE RecName: Full=Cytochrome c oxidase subunit 1 {ECO:0000256|RuleBase:RU000369}; DE EC=1.9.3.1 {ECO:0000256|RuleBase:RU000369}; DE Flags: Fragment; GN Name=COI {ECO:0000313|EMBL:AEW29130.1}; OS Chlorostoma argyrostoma turbinatum (Sea snail) (Tegula argyrostoma OS turbinatum). OG Mitochondrion {ECO:0000313|EMBL:AEW29130.1}. OC Eukaryota; Metazoa; Lophotrochozoa; Mollusca; Gastropoda; OC Vetigastropoda; Trochoidea; Trochidae; Chlorostoma. OX NCBI_TaxID=761901 {ECO:0000313|EMBL:AEW29130.1}; RN [1] {ECO:0000313|EMBL:AEW29130.1} RP NUCLEOTIDE SEQUENCE. RA Kim D.-W., Kim R.N., Kang D.W., Min H.K., Park H.C., Park Y.-H., RA Paek W.-K., Lim J.; RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:AEW29130.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=23166532; DOI=10.5808/GI.2012.10.3.206; RA Kim D.W., Yoo W.G., Park H.C., Yoo H.S., Kang D.W., Jin S.D., RA Min H.K., Paek W.K., Lim J.; RT "DNA barcoding of fish, insects, and shellfish in Korea."; RL Genomics Inform 10:206-211(2012). CC -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory CC chain that catalyzes the reduction of oxygen to water. Subunits 1- CC 3 form the functional core of the enzyme complex. CO I is the CC catalytic subunit of the enzyme. Electrons originating in CC cytochrome c are transferred via the copper A center of subunit 2 CC and heme A of subunit 1 to the bimetallic center formed by heme A3 CC and copper B. {ECO:0000256|RuleBase:RU000369}. CC -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4 CC ferricytochrome c + 2 H(2)O. {ECO:0000256|RuleBase:RU000369}. CC -!- PATHWAY: Energy metabolism; oxidative phosphorylation. CC {ECO:0000256|RuleBase:RU000369}. CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane CC {ECO:0000256|RuleBase:RU000369}; Multi-pass membrane protein CC {ECO:0000256|RuleBase:RU000369}. CC -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family. CC {ECO:0000256|RuleBase:RU000369}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; HM180516; AEW29130.1; -; Genomic_DNA. DR UniPathway; UPA00705; -. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. DR GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. DR GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:UniProtKB-EC. DR GO; GO:0020037; F:heme binding; IEA:InterPro. DR GO; GO:0005506; F:iron ion binding; IEA:InterPro. DR GO; GO:0009060; P:aerobic respiration; IEA:InterPro. DR GO; GO:0006119; P:oxidative phosphorylation; IEA:UniProtKB-UniPathway. DR Gene3D; 1.20.210.10; -; 1. DR InterPro; IPR023616; Cyt_c_oxase-like_su1_dom. DR InterPro; IPR000883; Cyt_C_Oxase_1. DR PANTHER; PTHR10422; PTHR10422; 1. DR Pfam; PF00115; COX1; 1. DR PRINTS; PR01165; CYCOXIDASEI. DR SUPFAM; SSF81442; SSF81442; 1. DR PROSITE; PS50855; COX1; 1. PE 3: Inferred from homology; KW Copper {ECO:0000256|RuleBase:RU000369}; KW Electron transport {ECO:0000256|RuleBase:RU000369}; KW Heme {ECO:0000256|RuleBase:RU000369}; KW Iron {ECO:0000256|RuleBase:RU000369}; KW Membrane {ECO:0000256|RuleBase:RU000369, ECO:0000256|SAM:Phobius}; KW Metal-binding {ECO:0000256|RuleBase:RU000369}; KW Mitochondrion {ECO:0000256|RuleBase:RU000369, KW ECO:0000313|EMBL:AEW29130.1}; KW Mitochondrion inner membrane {ECO:0000256|RuleBase:RU000369}; KW Oxidoreductase {ECO:0000256|RuleBase:RU000369}; KW Respiratory chain {ECO:0000256|RuleBase:RU000369}; KW Transmembrane {ECO:0000256|RuleBase:RU000369, KW ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}; KW Transport {ECO:0000256|RuleBase:RU000369}. FT TRANSMEM 7 25 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 45 71 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 134 159 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 171 198 Helical. {ECO:0000256|SAM:Phobius}. FT DOMAIN 1 229 COX1. {ECO:0000259|PROSITE:PS50855}. FT NON_TER 1 1 {ECO:0000313|EMBL:AEW29130.1}. FT NON_TER 229 229 {ECO:0000313|EMBL:AEW29130.1}. SQ SEQUENCE 229 AA; 24707 MW; 9B730598D4F0A327 CRC64; KDIGTLYLVF GIWSGLVGTA LSLLIRAELG QPGALLGDDQ LYNVIVTAHA FVMIFFLVMP LMIGGFGNWL IPLMLGAPDM AFPRLNNMSF WLLPPALTLL LSSAAVESGA GTGWTVYPPL ASNLAHAGAS VDLAIFSLHL AGISSILGAV NFITTVINMR WQGMSFERLP LFVWSVKITA ILLLLSLPVL AGAITMLLTD RNFNTSFFDP AGGGDPILYQ HLFWFFGHP //