ID G7Z069_ACISI Unreviewed; 499 AA. AC G7Z069; DT 25-JAN-2012, integrated into UniProtKB/TrEMBL. DT 25-JAN-2012, sequence version 1. DT 07-JAN-2015, entry version 15. DE SubName: Full=Hepatic lipase {ECO:0000313|EMBL:ACT22637.1}; GN Name=HL {ECO:0000313|EMBL:ACT22637.1}; OS Acipenser sinensis (Chinese sturgeon). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Chondrostei; Acipenseriformes; Acipenseridae; OC Acipenser. OX NCBI_TaxID=61970 {ECO:0000313|EMBL:ACT22637.1}; RN [1] {ECO:0000313|EMBL:ACT22637.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=20672411; DOI=10.3724/SP.J.1141.2010.03239; RA Huang Y., Liang X.F., Wang L., Li G.Z., Liu X.X., Yao Y.; RT "Molecular characterization and evolutional analysis of liportein RT lipase and hepatic lipase gene in Chinese Sturgeon and other six RT freshwater fishes."; RL Dong Wu Xue Yan Jiu 31:239-249(2010). CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase CC family. {ECO:0000256|RuleBase:RU004262}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; FJ436062; ACT22637.1; -; mRNA. DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW. DR GO; GO:0004806; F:triglyceride lipase activity; IEA:InterPro. DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro. DR Gene3D; 2.60.60.20; -; 1. DR Gene3D; 3.40.50.1820; -; 1. DR InterPro; IPR029058; AB_hydrolase. DR InterPro; IPR002333; Lipase_hep. DR InterPro; IPR016272; Lipase_LIPH. DR InterPro; IPR008976; Lipase_LipOase. DR InterPro; IPR013818; Lipase_N. DR InterPro; IPR001024; PLAT/LH2_dom. DR InterPro; IPR000734; TAG_lipase. DR PANTHER; PTHR11610; PTHR11610; 1. DR PANTHER; PTHR11610:SF2; PTHR11610:SF2; 1. DR Pfam; PF00151; Lipase; 1. DR Pfam; PF01477; PLAT; 1. DR PIRSF; PIRSF000865; Lipoprotein_lipase_LIPH; 1. DR PRINTS; PR00824; HEPLIPASE. DR PRINTS; PR00821; TAGLIPASE. DR SUPFAM; SSF49723; SSF49723; 1. DR SUPFAM; SSF53474; SSF53474; 1. DR PROSITE; PS50095; PLAT; 1. PE 2: Evidence at transcript level; KW Hydrolase {ECO:0000256|RuleBase:RU004263}; KW Secreted {ECO:0000256|SAAS:SAAS00131234}. FT ACT_SITE 167 167 Nucleophile. {ECO:0000256|PIRSR: FT PIRSR000865-1}. FT ACT_SITE 193 193 Charge relay system. {ECO:0000256|PIRSR: FT PIRSR000865-1}. FT ACT_SITE 278 278 Charge relay system. {ECO:0000256|PIRSR: FT PIRSR000865-1}. SQ SEQUENCE 499 AA; 56318 MW; 6FE046C7CF76C8F1 CRC64; MGIVRGLVFI LFIYHISDAK RLLVNKTDTK DKSQPILKQK VHYVPKSNFR LYTSGDAMDD TCTILPFDSG TLDRCSFNST APLVIIVHGW SVDGMLESWV TKLAAALKSK LRYSNVVIAD WLSLAHQHYA IAVQNTRLVG QEIADLLEWL EESHQFSTEN VHLIGYSLGA HVSGFAGSYV SGSRNIGRIT GLDPAGPLFE GMSYTDRLSP DDANFVDAIH TFTQQHMGLS VGIKQPVAHY DFYPNGAPFQ PGCHIKNLYD HLSQYGLSGF QQNVKCAHER SVHLFIDSLL NDDKQSMAYW CNDNKSFDKG ICLDCRKNRC NTLGYNIKKV RTGTSKRLYL KTRSHMPYKV YHYQFKIQFI NQIAQLEPML TISLMGTKED VQNLPITLVE EITGNKTYTL LITLDTDIGD LMVLKFKWEG SAVWANIWNK VQTIMPWRKG GKGPELTVGR IRVKAGETQK KTSFCSQSDD STHILPAQEK TFVRCERNSN RGKKKTTLA //