ID G7MJF8_MACMU Unreviewed; 198 AA. AC G7MJF8; DT 25-JAN-2012, integrated into UniProtKB/TrEMBL. DT 25-JAN-2012, sequence version 1. DT 14-DEC-2022, entry version 36. DE RecName: Full=Translocon-associated protein subunit gamma {ECO:0000256|ARBA:ARBA00022231}; DE AltName: Full=Signal sequence receptor subunit gamma {ECO:0000256|ARBA:ARBA00030917}; GN ORFNames=EGK_11971 {ECO:0000313|EMBL:EHH16650.1}; OS Macaca mulatta (Rhesus macaque). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; OC Cercopithecidae; Cercopithecinae; Macaca. OX NCBI_TaxID=9544 {ECO:0000313|EMBL:EHH16650.1}; RN [1] {ECO:0000313|EMBL:EHH16650.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CR-5 {ECO:0000313|EMBL:EHH16650.1}; RX PubMed=22002653; DOI=10.1038/nbt.1992; RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q., RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z., RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y., RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X., RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W., RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.; RT "Genome sequencing and comparison of two nonhuman primate animal models, RT the cynomolgus and Chinese rhesus macaques."; RL Nat. Biotechnol. 29:1019-1023(2011). CC -!- FUNCTION: TRAP proteins are part of a complex whose function is to bind CC calcium to the ER membrane and thereby regulate the retention of ER CC resident proteins. {ECO:0000256|ARBA:ARBA00002838}. CC -!- SUBUNIT: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP- CC gamma. {ECO:0000256|ARBA:ARBA00011819}. CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein CC {ECO:0000256|ARBA:ARBA00004477}. Membrane CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein CC {ECO:0000256|ARBA:ARBA00004141}. CC -!- SIMILARITY: Belongs to the TRAP-gamma family. CC {ECO:0000256|ARBA:ARBA00007990}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CM001254; EHH16650.1; -; Genomic_DNA. DR AlphaFoldDB; G7MJF8; -. DR HOGENOM; CLU_092935_0_0_1; -. DR Proteomes; UP000013456; Chromosome 2. DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. DR GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:InterPro. DR InterPro; IPR009779; SSR3. DR PANTHER; PTHR13399; TRANSLOCON-ASSOCIATED PROTEIN TRAP , GAMMA SUBUNIT; 1. DR Pfam; PF07074; TRAP-gamma; 1. PE 3: Inferred from homology; KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}. FT TRANSMEM 30..48 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 60..77 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 151..170 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 176..195 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" SQ SEQUENCE 198 AA; 22670 MW; C66D13A3C0CF89EB CRC64; MAPKGSSKQQ SEEDLLLQDF SRNLSAKSSA LFFGNAFIVS AIPIWLYWRI WHMDLIQSAV LYSVMTLVST YLVAFAYKNV KFVLKHKVAQ KREDAVSKEV TRKLSEADNR KMSRKEKDER FDSYLKYGHH KRGILWKKNE VADYEATTFS IFYNNTLFLV VVIVASFFIL KNFNPTVNYI LSISASSGLI ALLSTGSK //