ID G5EEG9_CAEEL Unreviewed; 399 AA. AC G5EEG9; DT 14-DEC-2011, integrated into UniProtKB/TrEMBL. DT 14-DEC-2011, sequence version 1. DT 14-DEC-2011, entry version 1. DE SubName: Full=Protein M05B5.5a, confirmed by transcript evidence; GN Name=hlh-2; ORFNames=M05B5.5a; OS Caenorhabditis elegans. OC Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; OC Rhabditidae; Peloderinae; Caenorhabditis. OX NCBI_TaxID=6239; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Bristol N2; RX MEDLINE=99069613; PubMed=9851916; DOI=10.1126/science.282.5396.2012; RG The C. elegans sequencing consortium; RT "Genome sequence of the nematode C. elegans: a platform for RT investigating biology."; RL Science 282:2012-2018(1998). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; Z71258; CAA95787.1; -; Genomic_DNA. DR EMBL; Z71265; CAA95787.1; JOINED; Genomic_DNA. DR EMBL; Z71265; CAA95837.1; -; Genomic_DNA. DR EMBL; Z71258; CAA95837.1; JOINED; Genomic_DNA. DR PIR; T18853; T18853. DR RefSeq; NP_001021581.1; NM_001026410.2. DR UniGene; Cel.5062; -. DR ProteinModelPortal; Q17588; -. DR SMR; Q17588; 303-363. DR IntAct; Q17588; 16. DR MINT; MINT-6668923; -. DR STRING; Q17588; -. DR PRIDE; Q17588; -. DR EnsemblMetazoa; M05B5.5a; M05B5.5a; M05B5.5. DR GeneID; 172458; -. DR KEGG; cel:M05B5.5; -. DR CTD; 172458; -. DR WormBase; M05B5.5a; CE06191; WBGene00001949; hlh-2. DR GeneTree; EMGT00050000012915; -. DR InParanoid; Q17588; -. DR OMA; DAMSSMY; -. DR NextBio; 875589; -. DR ArrayExpress; Q17588; -. DR GO; GO:0005737; C:cytoplasm; IDA:WormBase. DR GO; GO:0005634; C:nucleus; IDA:WormBase. DR GO; GO:0046982; F:protein heterodimerization activity; IPI:WormBase. DR GO; GO:0042803; F:protein homodimerization activity; IPI:WormBase. DR GO; GO:0001085; F:RNA polymerase II transcription factor binding; IPI:WormBase. DR GO; GO:0043565; F:sequence-specific DNA binding; IDA:WormBase. DR GO; GO:0010171; P:body morphogenesis; IMP:WormBase. DR GO; GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase. DR GO; GO:0007276; P:gamete generation; IMP:WormBase. DR GO; GO:0035262; P:gonad morphogenesis; IMP:WormBase. DR GO; GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase. DR GO; GO:0040039; P:inductive cell migration; IMP:WormBase. DR GO; GO:0014018; P:neuroblast fate specification; IMP:WormBase. DR GO; GO:0048666; P:neuron development; IMP:WormBase. DR GO; GO:0043068; P:positive regulation of programmed cell death; IMP:WormBase. DR GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:WormBase. DR GO; GO:0040026; P:positive regulation of vulval development; IMP:WormBase. DR GO; GO:0045138; P:tail tip morphogenesis; IMP:WormBase. DR GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:WormBase. DR GO; GO:0040025; P:vulval development; IMP:WormBase. DR InterPro; IPR011598; HLH_DNA-bd. DR Gene3D; G3DSA:4.10.280.10; HLH_DNA_bd; 1. DR Pfam; PF00010; HLH; 1. DR SMART; SM00353; HLH; 1. DR SUPFAM; SSF47459; HLH_basic; 1. DR PROSITE; PS50888; HLH; 1. PE 2: Evidence at transcript level; KW Complete proteome; Reference proteome. SQ SEQUENCE 399 AA; 43193 MW; 8E139D03E597863B CRC64; MADPNSQLTS ATTVATAAIA QPQVMLPNAY DYPYNIDPTT IQMPDYWSGY HLNPYPPMQT TDIDYSSAFL PTHPPTETPA SVAAPTSATS DIKPIHATSS TSTTAPSTAP APTSTTDVLE LKPTTAPATN SAETSAIVAP QPLTNLTAPI DAMSSMYTWP QTYPGYLPPS EDNKASEAVN PYISIPPTYT FGADPSVADF SSYQQQLAGQ PNGLGGDTNL VDYNHQFPPA GMSPHFDPNG YPGMTGMPPG SSASSVRNDK SASRATSRRR VQGPPSSGIP TRHSSSSRLS DNESMSDDKD TDRRSQNNAR ERVRVRDINS AFKELGRMCT QHNQNTERNQ TKLGILHNAV SVITQLEEQV RQRNMNPKVM AGMKRKPDDD KMKMLDDNAP SAQFGHPRF //