ID G3X8W6_MOUSE Unreviewed; 466 AA. AC G3X8W6; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 1. DT 07-OCT-2020, entry version 70. DE SubName: Full=Regulator of G-protein-signaling 11 {ECO:0000313|Ensembl:ENSMUSP00000025020}; GN Name=Rgs11 {ECO:0000313|Ensembl:ENSMUSP00000025020, GN ECO:0000313|MGI:MGI:1354739}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000025020, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000025020, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000025020, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000025020} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000025020}; RG Ensembl; RL Submitted (SEP-2011) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC126438; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR RefSeq; NP_001074538.1; NM_001081069.1. DR SMR; G3X8W6; -. DR Antibodypedia; 22598; 141 antibodies. DR Ensembl; ENSMUST00000025020; ENSMUSP00000025020; ENSMUSG00000024186. DR GeneID; 50782; -. DR KEGG; mmu:50782; -. DR UCSC; uc008bdr.1; mouse. DR CTD; 8786; -. DR MGI; MGI:1354739; Rgs11. DR GeneTree; ENSGT00940000160198; -. DR KO; K16449; -. DR OrthoDB; 415625at2759; -. DR TreeFam; TF351956; -. DR BioGRID-ORCS; 50782; 0 hits in 18 CRISPR screens. DR ChiTaRS; Rgs11; mouse. DR Proteomes; UP000000589; Chromosome 17. DR Bgee; ENSMUSG00000024186; Expressed in pancreas and 210 other tissues. DR ExpressionAtlas; G3X8W6; baseline and differential. DR GO; GO:0032991; C:protein-containing complex; IEA:Ensembl. DR GO; GO:0031681; F:G-protein beta-subunit binding; IEA:Ensembl. DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro. DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro. DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW. DR CDD; cd00068; GGL; 1. DR Gene3D; 1.10.10.10; -; 1. DR Gene3D; 4.10.260.10; -; 1. DR InterPro; IPR000591; DEP_dom. DR InterPro; IPR015898; G-protein_gamma-like_dom. DR InterPro; IPR036284; GGL_sf. DR InterPro; IPR016137; RGS. DR InterPro; IPR040759; RGS_DHEX. DR InterPro; IPR036305; RGS_sf. DR InterPro; IPR036388; WH-like_DNA-bd_sf. DR InterPro; IPR036390; WH_DNA-bd_sf. DR Pfam; PF00610; DEP; 1. DR Pfam; PF00631; G-gamma; 1. DR Pfam; PF00615; RGS; 1. DR Pfam; PF18148; RGS_DHEX; 1. DR PRINTS; PR01301; RGSPROTEIN. DR SMART; SM00049; DEP; 1. DR SMART; SM00224; GGL; 1. DR SMART; SM00315; RGS; 1. DR SUPFAM; SSF46785; SSF46785; 1. DR SUPFAM; SSF48097; SSF48097; 1. DR SUPFAM; SSF48670; SSF48670; 1. DR PROSITE; PS50186; DEP; 1. DR PROSITE; PS50132; RGS; 1. PE 4: Predicted; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Signal transduction inhibitor {ECO:0000256|ARBA:ARBA00022700}. SQ SEQUENCE 466 AA; 53643 MW; 99675728D6EBA09C CRC64; MAMVTRCTPH GGCSRMQRPH LSKMERVVVS MQDPDQGVKM RSQRLLITVI PHAVAGRDLV EWLVQKFCIL EDEALHLGTL LAQHGYIYPL RESRDLTLRP DETPYRFQTP YFWTSTMWPA AELDYAIYLA KKNIQKQGAL VDYEKEHYAL LHKKINHAWD LVLMQAREQL RAAKQRRKGD RMVISCQEQT YWLVNKPPPG APNILEQGPE RGSYNPSHMQ MSSDFYKCEI ECFRKALGRN RVKSSACLEA YLKFSSQHGP HDPIMSGCLP SNPWITDDVT YWAMNAPNVA APTKLRVERW SFSFRELLDD PVGRAHFMDF LQKEFSAENL SFWEACEELR FGGQAQVPTL VDSVYQQFLA PGAARWINID SRTMERTLEG LRQPHRYVLD AAQLHIYMLM KKDSYPRFLK SDIYKGLLEE AVIPLETKRW PFPFLRKPLH SSPSPALQST PREPAATSSP EGADGE //