ID G3V2K4_HUMAN Unreviewed; 167 AA. AC G3V2K4; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 05-OCT-2016, sequence version 8. DT 24-JUL-2024, entry version 72. DE SubName: Full=Brain-enriched guanylate kinase-associated protein {ECO:0000313|Ensembl:ENSP00000450722}; DE Flags: Fragment; GN Name=BEGAIN {ECO:0000313|Ensembl:ENSP00000450722}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000450722, ECO:0000313|Proteomes:UP000005640}; RN [1] {ECO:0000313|Ensembl:ENSP00000450722, ECO:0000313|Proteomes:UP000005640} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=12508121; DOI=10.1038/nature01348; RA Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C., RA Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A., RA Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H., RA Du H., Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T., RA Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B., RA Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D., RA Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R., RA Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S., RA Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C., RA Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S., RA Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., RA Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., RA Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M., RA Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V., RA Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J., RA Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F., RA Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F., RA Waterston R., Hood L., Weissenbach J.; RT "The DNA sequence and analysis of human chromosome 14."; RL Nature 421:601-607(2003). RN [2] {ECO:0000313|Ensembl:ENSP00000450722} RP IDENTIFICATION. RG Ensembl; RL Submitted (SEP-2011) to UniProtKB. RN [3] {ECO:0007829|PubMed:22814378} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=22814378; DOI=10.1073/pnas.1210303109; RA Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., RA Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., RA Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.; RT "N-terminal acetylome analyses and functional insights of the N-terminal RT acetyltransferase NatB."; RL Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL163974; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL845552; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; KF456008; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR AlphaFoldDB; G3V2K4; -. DR SMR; G3V2K4; -. DR MassIVE; G3V2K4; -. DR PeptideAtlas; G3V2K4; -. DR ProteomicsDB; 32662; -. DR Antibodypedia; 146; 210 antibodies from 27 providers. DR Ensembl; ENST00000557378; ENSP00000450722; ENSG00000183092. DR UCSC; uc059ffh.1; human. DR HGNC; HGNC:24163; BEGAIN. DR OpenTargets; ENSG00000183092; -. DR VEuPathDB; HostDB:ENSG00000183092; -. DR OMA; MHRTSHH; -. DR ChiTaRS; BEGAIN; human. DR Proteomes; UP000005640; Chromosome 14. DR Bgee; ENSG00000183092; Expressed in right hemisphere of cerebellum and 112 other cell types or tissues. DR ExpressionAtlas; G3V2K4; baseline and differential. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell. DR InterPro; IPR043441; Tjap1/BEGAIN. DR PANTHER; PTHR28664:SF2; BRAIN-ENRICHED GUANYLATE KINASE-ASSOCIATED PROTEIN; 1. DR PANTHER; PTHR28664; TIGHT JUNCTION-ASSOCIATED PROTEIN 1; 1. PE 1: Evidence at protein level; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Membrane {ECO:0000256|ARBA:ARBA00023136}; KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}; KW Proteomics identification {ECO:0007829|PeptideAtlas:G3V2K4, KW ECO:0007829|ProteomicsDB:G3V2K4}; KW Reference proteome {ECO:0000313|Proteomes:UP000005640}. FT COILED 36..77 FT /evidence="ECO:0000256|SAM:Coils" FT NON_TER 167 FT /evidence="ECO:0000313|Ensembl:ENSP00000450722" SQ SEQUENCE 167 AA; 19800 MW; 55B2E30D811846FA CRC64; MEKLSALQEQ KGELRKRLSY TTHKLEKLET EFDSTRHYLE IELRRAQEEL EKVTEKLRRI QSNYMALQRI NQELEDKLYR MGQHYEEEKR ALSHEIVALN SHLLEAKVTI DKLSEDNELY RKDCNLAAQL LQCSQTYGRV HKVSELPSDF QERVSLHMEK HGCSLPS //