ID G3UW82_MOUSE Unreviewed; 1942 AA. AC G3UW82; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 1. DT 19-MAR-2014, entry version 22. DE SubName: Full=MCG140437, isoform CRA_d; DE SubName: Full=Protein Myh2; GN Name=Myh2; ORFNames=mCG_140437; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=Mixed; RX PubMed=12040188; DOI=10.1126/science.1069193; RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., RA Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., RA Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W., RA Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., RA Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., RA Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., RA Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., RA Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., RA Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., RA Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., RA Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., RA Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., RA Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., RA Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., RA Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., RA Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., RA Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., RA Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., RA Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., RA Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., RA Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., RA Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., RA Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., RA Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., RA Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., RA Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., RA Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., RA Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., RA Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., RA Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., RA Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., RA Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.; RT "A comparison of whole-genome shotgun-derived mouse chromosome 16 and RT the human genome."; RL Science 296:1661-1671(2002). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=Mixed; RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.; RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [4] RP IDENTIFICATION. RC STRAIN=C57BL/6J; RG Ensembl; RL Submitted (JUN-2011) to UniProtKB. RN [5] RP IDENTIFICATION. RC STRAIN=C57BL/6J; RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- SIMILARITY: Contains IQ domain. CC -!- SIMILARITY: Contains myosin head-like domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL596129; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; CH466601; EDL10428.1; -; Genomic_DNA. DR RefSeq; NP_001034634.2; NM_001039545.2. DR RefSeq; XP_006532474.1; XM_006532411.1. DR UniGene; Mm.422801; -. DR Ensembl; ENSMUST00000018641; ENSMUSP00000018641; ENSMUSG00000033196. DR Ensembl; ENSMUST00000170159; ENSMUSP00000129544; ENSMUSG00000033196. DR GeneID; 17882; -. DR KEGG; mmu:17882; -. DR UCSC; uc007jmd.2; mouse. DR CTD; 4620; -. DR MGI; MGI:1339710; Myh2. DR GeneTree; ENSGT00720000108596; -. DR KO; K10352; -. DR OMA; QITSNRK; -. DR OrthoDB; EOG7RBZ7G; -. DR TreeFam; TF314375; -. DR NextBio; 292681; -. DR PRO; PR:G3UW82; -. DR GO; GO:0031672; C:A band; IDA:MGI. DR GO; GO:0005826; C:actomyosin contractile ring; IDA:MGI. DR GO; GO:0005925; C:focal adhesion; IEA:Ensembl. DR GO; GO:0005794; C:Golgi apparatus; IMP:MGI. DR GO; GO:0005859; C:muscle myosin complex; ISO:MGI. DR GO; GO:0005730; C:nucleolus; IEA:Ensembl. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0003774; F:motor activity; IEA:InterPro. DR GO; GO:0008152; P:metabolic process; IEA:GOC. DR GO; GO:0001778; P:plasma membrane repair; IMP:MGI. DR GO; GO:0014823; P:response to activity; IDA:MGI. DR Gene3D; 4.10.270.10; -; 1. DR InterPro; IPR000048; IQ_motif_EF-hand-BS. DR InterPro; IPR027401; Myosin-like_IQ_dom. DR InterPro; IPR015650; Myosin_1/23/4/6/7/8/13/15. DR InterPro; IPR001609; Myosin_head_motor_dom. DR InterPro; IPR004009; Myosin_N. DR InterPro; IPR002928; Myosin_tail. DR InterPro; IPR027417; P-loop_NTPase. DR PANTHER; PTHR13140:SF22; PTHR13140:SF22; 1. DR Pfam; PF00063; Myosin_head; 1. DR Pfam; PF02736; Myosin_N; 1. DR Pfam; PF01576; Myosin_tail_1; 1. DR PRINTS; PR00193; MYOSINHEAVY. DR SMART; SM00015; IQ; 2. DR SMART; SM00242; MYSc; 1. DR SUPFAM; SSF52540; SSF52540; 1. DR PROSITE; PS50096; IQ; 1. PE 4: Predicted; KW Actin-binding; ATP-binding; Coiled coil; Complete proteome; KW Motor protein; Myosin; Nucleotide-binding; Reference proteome. SQ SEQUENCE 1942 AA; 223219 MW; 9087D534CB3C4AD7 CRC64; MSSDAEMAVF GEAAPYLRKS EKERIEAQNR PFDAKTSVFV AEPKESFVKG TIQSKDAGKV TVKTEAGATL TVKEDQIFPM NPPKYDKIED MAMMTHLHEP AVLYNLKERY AAWMIYTYSG LFCVTVNPYK WLPVYNPEVV AAYRGKKRQE APPHIFSISD NAYQFMLTDR ENQSILITGE SGAGKTVNTK RVIQYFATIA VTGDKKKEEA TSGKMQGTLE DQIISANPLL EAFGNAKTVR NDNSSRFGKF IRIHFGTTGK LASADIETYL LEKSRVTFQL KAERSYHIFY QITSNKKPEL IEMLLITTNP YDYPFVSQGE ISVASIDDQE ELMATDSAID ILGFTNDEKV SIYKLTGAVM HYGNMKFKQK QREEQAEPDG TEVADKAAYL QGLNSADLLK ALCYPRVKVG NEYVTKGQTV EQVTNAVGAL AKAMYEKMFL WMVTRINQQL DTKQPRQYFI GVLDIAGFEI FDFNSLEQLC INFTNEKLQQ FFNHHMFVLE QEEYKKEGIE WTFIDFGMDL AACIELIEKP MGIFSILEEE CMFPKATDTS FKNKLYEQHL GKSANFQKPK VVKGKAEAHF SLIHYAGTVD YNITGWLDKN KDPLNETVVG LYQKSSVKTL AYLFSGAQTA EAEASSGGAA KKGAKKKGSS FQTVSALFRE NLNKLMTNLR STHPHFVRCI IPNETKTPGA MEHELVLHQL RCNGVLEGIR ICRKGFPSRI LYADFKQRYK VLNASAIPEG QYIDSKKASE KLLGSIDIDH TQYKFGHTKV FFKAGLLGLL EEMRDDKLAQ LITRTQAMCR GFLARVEYQK MVERRESIFC IQYNIRAFMN VKHWPWMKLF FKIKPLLKSA ETEKEMATMK EEFQKTKDDL AKSEAKRKEL EEKMVSLLKE KNDLQLQVQA EAEGLADAEE RCDQLIKTKI QLEAKIKEVT ERAEDEEEIN AELTAKKRKL EDECSELKKD IDDLELTLAK VEKEKHATEN KVKNLTEEMA GLDETIAKLT KEKKALQEAH QQTLDDLQAE EDKVNTLTKA KIKLEQQVDD LEGSLEQEKK LRMDLERAKR KLEGDLKLAQ ESIMDIENEK QQLDERLKKK EFEMSNLQSK IEDEQAIGIQ LQKKIKELQA RIEELEEEIE AERASRAKAE KQRSDLSREL EEISERLEEA GGATSAQIEM NKKREAEFQK MRRDLEEATL QHEATAATLR KKHADSVAEL GEQIDNLQRV KQKLEKEKSE MKMEIDDLAS NVETVSKAKG NLEKMCRTLE DQVSELKSKE EEQQRLINDL TTQRGRLQTE SGEFSRQLDE KEALVSQLSR GKQAFTQQIE ELKRQLEEEV KAKNALAHAL QSSRHDCDLL REQYEEEQES KAELQRALSK ANSEVAQWRT KYETDAIQRT EELEEAKKKL AQRLQAAEEH VEAVNAKCAS LEKTKQRLQN EVEDLMLDVE RTNAACAALD KKQRNFDKIL AEWKQKYEET HAELEASQKE ARSLGTELFK MKNAYEESLD QLETLKRENK NLQQEISDLT EQIAEGGKRI HELEKIKKQV EQEKCELQAA LEEAEASLEH EEGKILRIQL ELNQVKSEID RKIAEKDEEI DQLKRNHIRV VESMQSTLDA EIRSRNDAIR IKKKMEGDLN EMEIQLNHSN RMAAEALRNY RNTQGILKDT QLHLDDALRG QEDLKEQLAM VERRANLLQA EIEELRATLE QTERSRKIAE QELLDASERV QLLHTQNTSL INTKKKLETD ISQIQGEMED IVQEARNAEE KAKKAITDAA MMAEELKKEQ DTSAHLERMK KNMEQTVKDL QLRLDEAEQL ALKGGKKQIQ KLEARVRELE GEVESEQKRN AEAVKGLRKH ERRVKELTYQ TEEDRKNILR LQDLVDKLQA KVKSYKRQAE EAEEQSNTNL SKFRKIQHEL EEAEERADIA ESQVNKLRVK SREVHTKIIS EE //