ID G3PXI0_GASAC Unreviewed; 230 AA. AC G3PXI0; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 27-NOV-2024, sequence version 2. DT 27-NOV-2024, entry version 41. DE SubName: Full=FSHD region gene 1 {ECO:0000313|Ensembl:ENSGACP00000022319.2}; OS Gasterosteus aculeatus aculeatus (three-spined stickleback). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae; OC Gasterosteus. OX NCBI_TaxID=481459 {ECO:0000313|Ensembl:ENSGACP00000022319.2, ECO:0000313|Proteomes:UP000007635}; RN [1] {ECO:0000313|Ensembl:ENSGACP00000022319.2, ECO:0000313|Proteomes:UP000007635} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Lake Benthic {ECO:0000313|Ensembl:ENSGACP00000022319.2, RC ECO:0000313|Proteomes:UP000007635}; RX PubMed=33598708; RA Nath S., Shaw D.E., White M.A.; RT "Improved contiguity of the threespine stickleback genome using long-read RT sequencing."; RL G3 (Bethesda) 11:0-0(2021). RN [2] {ECO:0000313|Ensembl:ENSGACP00000022319.2} RP IDENTIFICATION. RG Ensembl; RL Submitted (AUG-2024) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus CC {ECO:0000256|ARBA:ARBA00004604}. CC -!- SIMILARITY: Belongs to the FRG1 family. CC {ECO:0000256|ARBA:ARBA00010878}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR AlphaFoldDB; G3PXI0; -. DR Ensembl; ENSGACT00000022361.2; ENSGACP00000022319.2; ENSGACG00000016888.2. DR GeneTree; ENSGT00390000004552; -. DR Proteomes; UP000007635; Chromosome IX. DR Bgee; ENSGACG00000016888; Expressed in embryo and 13 other cell types or tissues. DR GO; GO:0071013; C:catalytic step 2 spliceosome; IEA:TreeGrafter. DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. DR GO; GO:0055120; C:striated muscle dense body; IEA:TreeGrafter. DR GO; GO:0051015; F:actin filament binding; IEA:TreeGrafter. DR GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW. DR FunFam; 2.80.10.50:FF:000031; FRG1 isoform 1; 1. DR Gene3D; 2.80.10.50; -; 1. DR InterPro; IPR008999; Actin-crosslinking. DR InterPro; IPR010414; FRG1. DR PANTHER; PTHR12928; FRG1 PROTEIN; 1. DR PANTHER; PTHR12928:SF0; FSHD REGION GENE 1; 1. DR Pfam; PF06229; FRG1; 1. DR SUPFAM; SSF50405; Actin-crosslinking proteins; 1. PE 3: Inferred from homology; KW Nucleus {ECO:0000256|ARBA:ARBA00023242}; KW Reference proteome {ECO:0000313|Proteomes:UP000007635}. SQ SEQUENCE 230 AA; 25197 MW; ADBB451E85F13869 CRC64; MAEYSHVKST KLVLKGLNKG KKRKHKDNKK KAGDDEEKAD IVDGWWAISN FGEISGSVAI EMQNNAYIHA MDSGLFTLGA PHKADEGPDP PEQFTAVKLS DTRIALKSGY GKYLGITSEG LVVGRSDAIG SREQWETVFE NGKMALMAAN SCFISYSESG DIVAKSKTAG EGEMVKIRSS VEQEVKHKDD IAEEDRGNVK SCEVNYVYVT FVPCAHKRSS QQQIKASLCI //