ID G3MTY7_CAEEL Unreviewed; 711 AA. AC G3MTY7; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 1. DT 16-JAN-2019, entry version 61. DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CCD31094.1}; GN Name=spe-41 {ECO:0000313|EMBL:CCD31094.1, GN ECO:0000313|WormBase:K01A11.4b}; GN ORFNames=CELE_K01A11.4 {ECO:0000313|EMBL:CCD31094.1}, K01A11.4 GN {ECO:0000313|WormBase:K01A11.4b}; OS Caenorhabditis elegans. OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; OC Caenorhabditis. OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCD31094.1, ECO:0000313|Proteomes:UP000001940}; RN [1] {ECO:0000313|EMBL:CCD31094.1, ECO:0000313|Proteomes:UP000001940} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CCD31094.1, RC ECO:0000313|Proteomes:UP000001940}; RX PubMed=9851916; DOI=https://doi.org/10.1126/science.282.5396.2012; RG The C. elegans sequencing consortium; RA Sulson J.E., Waterston R.; RT "Genome sequence of the nematode C. elegans: a platform for RT investigating biology."; RL Science 282:2012-2018(1998). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BX284603; CCD31094.1; -; Genomic_DNA. DR RefSeq; NP_001254873.1; NM_001267944.1. DR UniGene; Cel.18109; -. DR ProteinModelPortal; G3MTY7; -. DR EnsemblMetazoa; K01A11.4b; K01A11.4b; WBGene00004976. DR GeneID; 175446; -. DR CTD; 175446; -. DR WormBase; K01A11.4b; CE46278; WBGene00004976; spe-41. DR eggNOG; KOG3609; Eukaryota. DR eggNOG; ENOG410XQ0Y; LUCA. DR GeneTree; ENSGT00940000153138; -. DR OrthoDB; 1018075at2759; -. DR Reactome; R-CEL-114508; Effects of PIP2 hydrolysis. DR Reactome; R-CEL-139853; Elevation of cytosolic Ca2+ levels. DR Reactome; R-CEL-3295583; TRP channels. DR Proteomes; UP000001940; Chromosome III. DR Bgee; WBGene00004976; Expressed in 4 organ(s), highest expression level in material anatomical entity. DR GO; GO:0034703; C:cation channel complex; IBA:GO_Central. DR GO; GO:0031410; C:cytoplasmic vesicle; IDA:WormBase. DR GO; GO:0005887; C:integral component of plasma membrane; IDA:WormBase. DR GO; GO:0031260; C:pseudopodium membrane; IDA:WormBase. DR GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IBA:GO_Central. DR GO; GO:0015279; F:store-operated calcium channel activity; IDA:WormBase. DR GO; GO:0070588; P:calcium ion transmembrane transport; IBA:GO_Central. DR GO; GO:0006816; P:calcium ion transport; IDA:WormBase. DR GO; GO:0006874; P:cellular calcium ion homeostasis; IMP:WormBase. DR GO; GO:0006828; P:manganese ion transport; IBA:GO_Central. DR GO; GO:0051480; P:regulation of cytosolic calcium ion concentration; IBA:GO_Central. DR GO; GO:0007338; P:single fertilization; IMP:WormBase. DR InterPro; IPR013555; TRP_dom. DR InterPro; IPR002153; TRPC_channel. DR PANTHER; PTHR10117; PTHR10117; 1. DR Pfam; PF08344; TRP_2; 1. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000001940}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000001940}; KW Signal {ECO:0000256|SAM:SignalP}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT SIGNAL 1 18 {ECO:0000256|SAM:SignalP}. FT CHAIN 19 711 {ECO:0000256|SAM:SignalP}. FT /FTId=PRO_5003447489. FT TRANSMEM 184 203 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 224 244 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 289 310 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 330 353 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 374 395 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 428 446 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 466 488 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 508 534 Helical. {ECO:0000256|SAM:Phobius}. FT DOMAIN 34 89 TRP_2. {ECO:0000259|Pfam:PF08344}. SQ SEQUENCE 711 AA; 80958 MW; BEACD74448919507 CRC64; MTPLMLACIL NNFSIVQCLI TRGHCIQIPH FITCECKTCK RETVTTHSST RLVDVMRALS SEAYLWLATD DVFAATCAVA RDLQQLASDD QLEYVETYRD LEMNVQRFLC RISDQAWRVD EFNMMVANRN YCPERMTEIS SPRLQMAMDS QMRQFTCSTN SQTTIKSVFR SDWYNYGIKP KRDAWRFLRA CILMPFLVML HAFMPTKGTT MCVPLARFIA HITMYLVFLI AAILRPTIGF YFAWTDSIEV TVQALEIFMY AYVMGLALEK GILFYRVGRD GFFAFWWRWF DAALIFIFLF SLIFFTGKWG KREAFDPSSV DRMHWPSFEF SLLHEICLAI ACVLSILKCF YYAQMMKSIG GSVISVGKCV GKTYTYILIM VAIIVSFSVG LNIIVDPYLN RSTMKIGDQD YTKTTDSYET IGTSSKNLFW SIFGYLGPST FTTVVGNTGP NMDPVKHTLN SSTFEILAAV YHGILIITVL NLMTSILVKG ADEVLDNEEM EFKFTRAAIY SEFLSWEMAA PPPLNLILVV AHFVHRNLLK RYYASPAWGE KPANDDVEDQ AADEQYMQLL MVVFARFVAS KECKYKSIWR SEFHREEKQP PRVTFLTTGA HSFLMDNTFE GFKMRSSRTM EAEGYKEYTT VQYYVPKSKT PGPAAAADAG TKVAPKDDKP QNNPVLARTG IDSPVPSSKQ VMSSELSASI PRARDVTFLG V //