ID G3MRD1_9ACAR Unreviewed; 487 AA. AC G3MRD1; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 1. DT 14-MAY-2014, entry version 8. DE RecName: Full=Phosphatidylinositol-glycan biosynthesis class W protein; DE EC=2.3.-.-; OS Amblyomma maculatum (Gulf Coast tick). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; OC Acari; Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Amblyomminae; OC Amblyomma. OX NCBI_TaxID=34609; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Salivary gland; RA Ribeiro J.M.C., Karim S.; RT "A deep insight into the sialotranscriptome of the Gulf Coast tick, RT Amblyomma maculatum."; RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Probable acetyltransferase, which acetylates the CC inositol ring of phosphatidylinositol during biosynthesis of GPI- CC anchor (By similarity). CC -!- PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol- CC anchor biosynthesis. CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Multi-pass CC membrane protein (By similarity). CC -!- SIMILARITY: Belongs to the PIGW family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JO844432; AEO36049.1; -; mRNA. DR UniPathway; UPA00196; -. DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW. DR GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:UniProtKB-UniPathway. DR InterPro; IPR009447; GWT1. DR PANTHER; PTHR20661; PTHR20661; 1. DR Pfam; PF06423; GWT1; 1. PE 2: Evidence at transcript level; KW Acyltransferase; Endoplasmic reticulum; GPI-anchor biosynthesis; KW Membrane; Transferase; Transmembrane; Transmembrane helix. SQ SEQUENCE 487 AA; 53463 MW; D8294698F053C2D5 CRC64; MDTSEKALHK AFVTSKDGCS PVQLLLRGGL LIYSTLLHAA LAELPVIKSR RKNVWFSATF AVAVQCVPFI LSFTLLAEYW ACVVFTVIAV TLGIRILQRL FDQHSVVKSH RKNVPGKRPI AKVAPHDYPG LTSARAQVIL MTVFGILAVD FATVPRYFAK TEKTGFSPMD LGVGAFVIIV AVSSREAKNS LPANRWKNVW KALRGSVALI ILGLVRLFMV TALNYQNPVH EYGIHWNFFF TLACTRVLTS VVYASVSIHL DLAVAVMLGC AYEACLLFTP LAAFLDSDER SGFLAANKEG LMSIVGYVAL HLAAAGTARM LGYKPRNCAR DWIMTGLQAA GISVAIFAAT YIMHTSVDPV SRRLANLSYC LWMYSLGVFA VALSVGVTLA NTALLPRSAQ VDYNLFAVSH ADSLNTDVDI LWKSINYNGM AVFLLANILT GLVNIFFHPR TASDIVCFVT LVGYTYVLCI FAVFLHRKMV KLKLPFT //