ID G3MRD1_9ACAR Unreviewed; 487 AA. AC G3MRD1; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 1. DT 04-FEB-2015, entry version 11. DE RecName: Full=Phosphatidylinositol-glycan biosynthesis class W protein {ECO:0000256|RuleBase:RU280819}; DE EC=2.3.-.- {ECO:0000256|RuleBase:RU280819}; OS Amblyomma maculatum (Gulf Coast tick). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; OC Acari; Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Amblyomminae; OC Amblyomma. OX NCBI_TaxID=34609 {ECO:0000313|EMBL:AEO36049.1}; RN [1] {ECO:0000313|EMBL:AEO36049.1} RP NUCLEOTIDE SEQUENCE. RC TISSUE=Salivary gland {ECO:0000313|EMBL:AEO36049.1}; RA Ribeiro J.M.C., Karim S.; RT "A deep insight into the sialotranscriptome of the Gulf Coast tick, RT Amblyomma maculatum."; RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Probable acetyltransferase, which acetylates the CC inositol ring of phosphatidylinositol during biosynthesis of GPI- CC anchor. {ECO:0000256|RuleBase:RU280819}. CC -!- PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol- CC anchor biosynthesis. {ECO:0000256|RuleBase:RU280819}. CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane CC {ECO:0000256|RuleBase:RU280819}; Multi-pass membrane protein CC {ECO:0000256|RuleBase:RU280819}. CC -!- SIMILARITY: Belongs to the PIGW family. CC {ECO:0000256|RuleBase:RU280819}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JO844432; AEO36049.1; -; mRNA. DR UniPathway; UPA00196; -. DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW. DR GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:UniProtKB-UniPathway. DR InterPro; IPR009447; GWT1. DR PANTHER; PTHR20661; PTHR20661; 1. DR Pfam; PF06423; GWT1; 1. PE 2: Evidence at transcript level; KW Acyltransferase {ECO:0000256|RuleBase:RU280819}; KW Endoplasmic reticulum {ECO:0000256|RuleBase:RU280819}; KW GPI-anchor biosynthesis {ECO:0000256|RuleBase:RU280819}; KW Membrane {ECO:0000256|RuleBase:RU280819}; KW Transferase {ECO:0000256|RuleBase:RU280819}; KW Transmembrane {ECO:0000256|RuleBase:RU280819}; KW Transmembrane helix {ECO:0000256|RuleBase:RU280819}. FT TRANSMEM 24 42 Helical. {ECO:0000256|RuleBase:RU280819}. FT TRANSMEM 54 71 Helical. {ECO:0000256|RuleBase:RU280819}. FT TRANSMEM 77 97 Helical. {ECO:0000256|RuleBase:RU280819}. FT TRANSMEM 138 159 Helical. {ECO:0000256|RuleBase:RU280819}. FT TRANSMEM 165 182 Helical. {ECO:0000256|RuleBase:RU280819}. FT TRANSMEM 202 222 Helical. {ECO:0000256|RuleBase:RU280819}. FT TRANSMEM 234 255 Helical. {ECO:0000256|RuleBase:RU280819}. FT TRANSMEM 262 284 Helical. {ECO:0000256|RuleBase:RU280819}. FT TRANSMEM 304 321 Helical. {ECO:0000256|RuleBase:RU280819}. FT TRANSMEM 333 352 Helical. {ECO:0000256|RuleBase:RU280819}. FT TRANSMEM 372 395 Helical. {ECO:0000256|RuleBase:RU280819}. FT TRANSMEM 427 447 Helical. {ECO:0000256|RuleBase:RU280819}. FT TRANSMEM 453 475 Helical. {ECO:0000256|RuleBase:RU280819}. SQ SEQUENCE 487 AA; 53463 MW; D8294698F053C2D5 CRC64; MDTSEKALHK AFVTSKDGCS PVQLLLRGGL LIYSTLLHAA LAELPVIKSR RKNVWFSATF AVAVQCVPFI LSFTLLAEYW ACVVFTVIAV TLGIRILQRL FDQHSVVKSH RKNVPGKRPI AKVAPHDYPG LTSARAQVIL MTVFGILAVD FATVPRYFAK TEKTGFSPMD LGVGAFVIIV AVSSREAKNS LPANRWKNVW KALRGSVALI ILGLVRLFMV TALNYQNPVH EYGIHWNFFF TLACTRVLTS VVYASVSIHL DLAVAVMLGC AYEACLLFTP LAAFLDSDER SGFLAANKEG LMSIVGYVAL HLAAAGTARM LGYKPRNCAR DWIMTGLQAA GISVAIFAAT YIMHTSVDPV SRRLANLSYC LWMYSLGVFA VALSVGVTLA NTALLPRSAQ VDYNLFAVSH ADSLNTDVDI LWKSINYNGM AVFLLANILT GLVNIFFHPR TASDIVCFVT LVGYTYVLCI FAVFLHRKMV KLKLPFT //