ID   G1E487_9TELE            Unreviewed;       194 AA.
AC   G1E487;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   16-MAY-2012, entry version 4.
DE   RecName: Full=Cytochrome c oxidase subunit 1;
DE            EC=1.9.3.1;
DE   Flags: Fragment;
GN   Name=COI;
OS   Notropis volucellus (mimic shiner).
OG   Mitochondrion.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Notropis.
OX   NCBI_TaxID=28797;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=21670289; DOI=10.1073/pnas.1016437108;
RA   April J., Mayden R.L., Hanner R.H., Bernatchez L.;
RT   "Genetic calibration of species diversity among North America's
RT   freshwater fishes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:10602-10607(2011).
CC   -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory
CC       chain that catalyzes the reduction of oxygen to water. Subunits 1-
CC       3 form the functional core of the enzyme complex. CO I is the
CC       catalytic subunit of the enzyme. Electrons originating in
CC       cytochrome c are transferred via the copper A center of subunit 2
CC       and heme A of subunit 1 to the bimetallic center formed by heme A3
CC       and copper B (By similarity).
CC   -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4
CC       ferricytochrome c + 2 H(2)O.
CC   -!- PATHWAY: Energy metabolism; oxidative phosphorylation.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass
CC       membrane protein (By similarity).
CC   -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family.
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DR   EMBL; JN027747; AEK04371.1; -; Genomic_DNA.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:EC.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0009060; P:aerobic respiration; IEA:InterPro.
DR   GO; GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.
DR   Gene3D; G3DSA:1.20.210.10; COX1; 1.
DR   InterPro; IPR000883; Cyt_c_Oxase_su1.
DR   InterPro; IPR023616; Cyt_c_Oxase_su1_dom.
DR   PANTHER; PTHR10422; COX1; 1.
DR   Pfam; PF00115; COX1; 1.
DR   PRINTS; PR01165; CYCOXIDASEI.
DR   SUPFAM; SSF81442; COX1; 1.
DR   PROSITE; PS50855; COX1; 1.
PE   3: Inferred from homology;
KW   Copper; Electron transport; Heme; Iron; Membrane; Metal-binding;
KW   Mitochondrion; Mitochondrion inner membrane; Oxidoreductase;
KW   Respiratory chain; Transmembrane; Transport.
FT   NON_TER       1      1
FT   NON_TER     194    194
SQ   SEQUENCE   194 AA;  20642 MW;  53B8F931554716BF CRC64;
     VGTALSLLIR AELSQPGSLL GDDQIYNVIV TAHAFVMIFF MVMPILIGGF GNWLVPLMIG
     APDMAFPRMN NMSFWLLPPS FLLLLASSGV EAGAGTGWTV YPPLAGNLAH AGASVDLTIF
     SLHLAGVSSI LGAVNFITTI INMKPPAISQ YQTPLFVWAV LVTAVLLLLS LPVLAAGITM
     LLTDRNLNTT FFDX
//