ID   G0S8Z5_CHATD            Unreviewed;       629 AA.
AC   G0S8Z5;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   12-APR-2017, entry version 28.
DE   RecName: Full=Mitochondrial Rho GTPase {ECO:0000256|PIRNR:PIRNR037488};
DE            EC=3.6.5.- {ECO:0000256|PIRNR:PIRNR037488};
GN   ORFNames=CTHT_0043990 {ECO:0000313|EMBL:EGS19906.1};
OS   Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC   Sordariomycetes; Sordariomycetidae; Sordariales; Chaetomiaceae;
OC   Chaetomium.
OX   NCBI_TaxID=759272 {ECO:0000313|Proteomes:UP000008066};
RN   [1] {ECO:0000313|EMBL:EGS19906.1, ECO:0000313|Proteomes:UP000008066}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 1495 / CBS 144.50 / IMI 039719
RC   {ECO:0000313|Proteomes:UP000008066};
RX   PubMed=21784248; DOI=10.1016/j.cell.2011.06.039;
RA   Amlacher S., Sarges P., Flemming D., van Noort V., Kunze R.,
RA   Devos D.P., Arumugam M., Bork P., Hurt E.;
RT   "Insight into structure and assembly of the nuclear pore complex by
RT   utilizing the genome of a eukaryotic thermophile.";
RL   Cell 146:277-289(2011).
CC   -!- FUNCTION: Mitochondrial GTPase involved in mitochondrial
CC       trafficking. {ECO:0000256|PIRNR:PIRNR037488}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane
CC       {ECO:0000256|PIRNR:PIRNR037488}; Single-pass type IV membrane
CC       protein {ECO:0000256|PIRNR:PIRNR037488}.
CC   -!- SIMILARITY: Belongs to the mitochondrial Rho GTPase family.
CC       {ECO:0000256|PIRNR:PIRNR037488}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00448}.
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DR   EMBL; GL988043; EGS19906.1; -; Genomic_DNA.
DR   RefSeq; XP_006694791.1; XM_006694728.1.
DR   EnsemblFungi; EGS19906; EGS19906; CTHT_0043990.
DR   GeneID; 18258437; -.
DR   KEGG; cthr:CTHT_0043990; -.
DR   KO; K07870; -.
DR   OrthoDB; EOG092C13Q5; -.
DR   Proteomes; UP000008066; Unassembled WGS sequence.
DR   GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR   GO; GO:0032865; C:ERMES complex; IEA:EnsemblFungi.
DR   GO; GO:0031307; C:integral component of mitochondrial outer membrane; IEA:InterPro.
DR   GO; GO:0005635; C:nuclear envelope; IEA:EnsemblFungi.
DR   GO; GO:0005509; F:calcium ion binding; IEA:EnsemblFungi.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:EnsemblFungi.
DR   GO; GO:0000001; P:mitochondrion inheritance; IEA:EnsemblFungi.
DR   GO; GO:1990456; P:mitochondrion-ER tethering; IEA:EnsemblFungi.
DR   GO; GO:0055091; P:phospholipid homeostasis; IEA:EnsemblFungi.
DR   GO; GO:0010821; P:regulation of mitochondrion organization; IEA:EnsemblFungi.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.238.10; -; 2.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR013566; EF_hand_assoc_1.
DR   InterPro; IPR013567; EF_hand_assoc_2.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR020860; MIRO_dom.
DR   InterPro; IPR021181; Mt_Rho_GTPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001806; Small_GTPase.
DR   Pfam; PF08355; EF_assoc_1; 1.
DR   Pfam; PF08356; EF_assoc_2; 1.
DR   Pfam; PF00071; Ras; 2.
DR   PIRSF; PIRSF037488; Mt_Rho_GTPase; 1.
DR   SMART; SM00054; EFh; 2.
DR   SUPFAM; SSF47473; SSF47473; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS50222; EF_HAND_2; 2.
DR   PROSITE; PS51423; MIRO; 2.
PE   3: Inferred from homology;
KW   Calcium {ECO:0000256|PIRNR:PIRNR037488, ECO:0000256|PROSITE-
KW   ProRule:PRU00448};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008066};
KW   GTP-binding {ECO:0000256|PIRNR:PIRNR037488};
KW   Hydrolase {ECO:0000256|PIRNR:PIRNR037488};
KW   Membrane {ECO:0000256|PIRNR:PIRNR037488};
KW   Mitochondrion {ECO:0000256|PIRNR:PIRNR037488};
KW   Mitochondrion outer membrane {ECO:0000256|PIRNR:PIRNR037488};
KW   Nucleotide-binding {ECO:0000256|PIRNR:PIRNR037488};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008066}.
FT   DOMAIN        1    145       Miro. {ECO:0000259|PROSITE:PS51423}.
FT   DOMAIN      187    222       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   DOMAIN      308    343       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   DOMAIN      419    575       Miro. {ECO:0000259|PROSITE:PS51423}.
FT   CA_BIND     200    211       {ECO:0000256|PROSITE-ProRule:PRU00448}.
SQ   SEQUENCE   629 AA;  70820 MW;  2A8977D4B5788C26 CRC64;
     MTTRTVRICV CGDEGTGKSS LIASFVKDTF VTNKIQSVLP TVTIPPTINT PEDVTTTIVD
     TSARPQDRTV LRKEIRRCNV ILLVYSDHYS YERVALFWMP YFRSLGVNVP VVLCANKSDL
     QGPGSTDKVV EEEMLPVMAE FREIDSCIRT SAKEQHNVIE LFWLCQKAVV YPIAPLYDHK
     EGQLKPACQA ALRRIFYLCD KDQDGYLNDK EFLSFHAKCF DDKPLPPEEL DNIKRTVSKA
     VPTSSVEKGL DMRGFLYLNK IYAEKGRQET IWIILRKHHY EDSLCLEDSF LHPRFDVPEF
     SSAELSPAGY RFFMDLFLTF DKDNDGGLND QELDALFAPT PGLPPSWIET NFPTTTVRNE
     AGHITLQGWL AQWSMTTFLE PKTTLEYLAY LGFEGPNARD STTAALKVTK PRKRRRRPGR
     VERNVVLCYI LGSSGAGKSS LLDAFLNRPF DTLYHPTIKP RRAVNSVELH GGRQVYLILE
     ELGELEPAIL ENQAKLDACD LICYAYDSSE PDSFSHIVEL RKRYPYLDEL PAVYTALKAD
     RDKTTQRSEL QPDAYTAALN MAAPLHVSVT WSSISELFVA LAEAATNPST AFPKSEEPPD
     RTSLYMALAA TSCAALAAVL IWRRSTNSA
//