ID F9WED8_TRYCI Unreviewed; 446 AA. AC F9WED8; DT 19-OCT-2011, integrated into UniProtKB/TrEMBL. DT 19-OCT-2011, sequence version 1. DT 14-OCT-2015, entry version 13. DE SubName: Full=WGS project CAEQ00000000 data, annotated contig 25 {ECO:0000313|EMBL:CCD15645.1}; GN ORFNames=TCIL3000_0_00740 {ECO:0000313|EMBL:CCD15645.1}; OS Trypanosoma congolense (strain IL3000). OC Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae; Trypanosoma; OC Nannomonas. OX NCBI_TaxID=1068625 {ECO:0000313|EMBL:CCD15645.1, ECO:0000313|Proteomes:UP000000702}; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=IL3000; RA Jackson A.P., Berry A., Allison H.C., Burton P., Anderson J., RA Aslett M., Brown R., Corton N., Harris D., Hauser H., Gamble J., RA Gilderthorp R., McQuillan J., Quail M.A., Sanders M., van Tonder A., RA Ginger M.L., Donelson J.E., Field M.C., Barry J.D., Berriman M., RA Hertz-Fowler C.; RT "Divergent evolution of antigenic variation in African trypanosomes."; RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Proteomes:UP000000702} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=IL3000 {ECO:0000313|Proteomes:UP000000702}; RA Jackson A.P., Berry A., Allison H.C., Burton P., Anderson J., RA Aslett M., Brown R., Corton N., Harris D., Hauser H., Gamble J., RA Gilderthorp R., McQuillan J., Quail M.A., Sanders M., Van Tonder A., RA Ginger M.L., Donelson J.E., Field M.C., Barry J.D., Berriman M., RA Hertz-Fowler C.; RT "Divergent evolution of antigenic variation in African trypanosomes."; RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|EMBL:CCD15645.1, ECO:0000313|Proteomes:UP000000702} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=IL3000 {ECO:0000313|EMBL:CCD15645.1, RC ECO:0000313|Proteomes:UP000000702}; RX PubMed=22331916; DOI=10.1073/pnas.1117313109; RA Jackson A.P., Berry A., Aslett M., Allison H.C., Burton P., RA Vavrova-Anderson J., Brown R., Browne H., Corton N., Hauser H., RA Gamble J., Gilderthorp R., Marcello L., McQuillan J., Otto T.D., RA Quail M.A., Sanders M.J., van Tonder A., Ginger M.L., Field M.C., RA Barry J.D., Hertz-Fowler C., Berriman M.; RT "Antigenic diversity is generated by distinct evolutionary mechanisms RT in African trypanosome species."; RL Proc. Natl. Acad. Sci. U.S.A. 109:3416-3421(2012). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:CCD15645.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CAEQ01001995; CCD15645.1; -; Genomic_DNA. DR Proteomes; UP000000702; Unassembled WGS sequence. DR GO; GO:0003847; F:1-alkyl-2-acetylglycerophosphocholine esterase activity; IEA:InterPro. DR GO; GO:0016042; P:lipid catabolic process; IEA:InterPro. DR Gene3D; 3.40.50.1820; -; 2. DR InterPro; IPR029058; AB_hydrolase. DR InterPro; IPR005065; PAF_acetylhydro. DR InterPro; IPR016715; PAF_acetylhydro_eukaryote. DR PANTHER; PTHR10272; PTHR10272; 1. DR Pfam; PF03403; PAF-AH_p_II; 1. DR PIRSF; PIRSF018169; PAF_acetylhydrolase; 1. DR SUPFAM; SSF53474; SSF53474; 1. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000000702}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000000702}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 32 52 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 58 80 Helical. {ECO:0000256|SAM:Phobius}. FT ACT_SITE 289 289 Nucleophile. {ECO:0000256|PIRSR: FT PIRSR018169-1}. FT ACT_SITE 319 319 Charge relay system. {ECO:0000256|PIRSR: FT PIRSR018169-1}. FT ACT_SITE 398 398 Charge relay system. {ECO:0000256|PIRSR: FT PIRSR018169-1}. SQ SEQUENCE 446 AA; 49450 MW; C52C319D684B473B CRC64; MPFWTQKDVA RLVRWSTESF FLGHSLPLRG RLTSLHFAPV SVALVSSFVM YLNGMSSMWS SLAVCIGVLV SGGMFIVFPL PVLRPIGGRY CVSIAHMDGR ASQQLPPVAV FYPTNMSPDI KGISYVPFDD SRFIRGVAAY AKLPYFFLKD FMLLRVGATM NAVQADILSN GRMPPIVVFS HGLAGYHRLY SCFAMDLAAR GAVVVSVGHC DNSASFMRDS TGEESAVYLK DYGWQVPKRE MQISKRVKEV RRVLERLGET DFWTDLGCSA SDAENFLSRR PQVHLSGHSF GGATALAVAL EESQNATKVV NVRSVFVYDP WMLPIQGEHF FKPLSDGSKA YCIPTVTIHS DDWVNDSESW SFFQKVKSVV LAQPSYASLG SDEREAKFRT LITRNTSHIS MVDIAVLSPV IHGKVNSVVS PRVQIMEWCN ALLQFARANT VVSDLS //