ID F9URK4_LACPL Unreviewed; 376 AA. AC F9URK4; DT 19-OCT-2011, integrated into UniProtKB/TrEMBL. DT 19-OCT-2011, sequence version 1. DT 13-NOV-2013, entry version 19. DE SubName: Full=Phosphoribosylaminoimidazole carboxylase,ATPase subunit; DE EC=4.1.1.21; GN Name=purK1; OrderedLocusNames=lp_2728; OS Lactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1). OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae; OC Lactobacillus. OX NCBI_TaxID=220668; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC BAA-793 / NCIMB 8826 / WCFS1; RX PubMed=12566566; DOI=10.1073/pnas.0337704100; RA Kleerebezem M., Boekhorst J., van Kranenburg R., Molenaar D., RA Kuipers O.P., Leer R., Tarchini R., Peters S.A., Sandbrink H.M., RA Fiers M.W.E.J., Stiekema W., Klein Lankhorst R.M., Bron P.A., RA Hoffer S.M., Nierop Groot M.N., Kerkhoven R., de Vries M., Ursing B., RA de Vos W.M., Siezen R.J.; RT "Complete genome sequence of Lactobacillus plantarum WCFS1."; RL Proc. Natl. Acad. Sci. U.S.A. 100:1990-1995(2003). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=WCFS1; RA Siezen R.J., Francke C., Renckens B., Boekhorst J., Wels M., RA Kleerebezem M., van Hijum S.A.F.T.; RT "Complete resequencing and reannotation of the Lactobacillus plantarum RT WCFS1 genome."; RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Contains ATP-grasp domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL935263; CCC79843.1; -; Genomic_DNA. DR RefSeq; YP_004890357.1; NC_004567.2. DR ProteinModelPortal; F9URK4; -. DR EnsemblBacteria; CCC79843; CCC79843; lp_2728. DR GeneID; 1063026; -. DR KEGG; lpl:lp_2728; -. DR KO; K01589; -. DR OMA; NSGHYTL; -. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0048037; F:cofactor binding; IEA:InterPro. DR GO; GO:0046872; F:metal ion binding; IEA:InterPro. DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. DR GO; GO:0004638; F:phosphoribosylaminoimidazole carboxylase activity; IEA:UniProtKB-EC. DR GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro. DR Gene3D; 3.30.1490.20; -; 1. DR Gene3D; 3.30.470.20; -; 1. DR Gene3D; 3.40.50.20; -; 1. DR InterPro; IPR005875; AIR_COase_ATPase-su. DR InterPro; IPR011761; ATP-grasp. DR InterPro; IPR003135; ATP-grasp_carboxylate-amine. DR InterPro; IPR013815; ATP_grasp_subdomain_1. DR InterPro; IPR013816; ATP_grasp_subdomain_2. DR InterPro; IPR006140; D-isomer_2_OHA_DH_NAD-bd. DR InterPro; IPR016185; PreATP-grasp_dom. DR InterPro; IPR011054; Rudment_hybrid_motif. DR Pfam; PF02826; 2-Hacid_dh_C; 1. DR Pfam; PF02222; ATP-grasp; 1. DR SUPFAM; SSF51246; SSF51246; 1. DR SUPFAM; SSF52440; SSF52440; 1. DR TIGRFAMs; TIGR01161; purK; 1. DR PROSITE; PS50975; ATP_GRASP; 1. PE 4: Predicted; KW ATP-binding; Complete proteome; Lyase; Nucleotide-binding; KW Purine biosynthesis; Reference proteome. SQ SEQUENCE 376 AA; 40503 MW; FC3B974763F63621 CRC64; MNANFKEALL PPATIGIVGG GQLGQMMTLS AKAMGYRVGV LDPTPKAPAA QVADFQIVAA YDDQAALLDL ARRSDVLTYE FENVDENALI AAQAYAKLPQ GTALLHITGD RLNEKQFLHD HGIPVTSFAP VTDLQSLNYA LNRVGTPAIL KTAAGGYDGH GQTDLDTAVV TKAASALLTQ PCILEARQKF RTEVSMMVTR SAAGVVTTFP LVENQHQHHI LHTTIAPANV QPSVHSAARK IAVSIAESLE LRGVLGIEFF VLPDDTLLVN ELAPRPHNSG HYTIEACNIS QFEAHIRSIC GLPIPAITQT SPAVMRNLLG DDLTVARQQL VEHPEWHFHD YGKAAIKPQR KMGHVTVLNH DIDAALASLA NLKGEQ //