ID   F9URK4_LACPL            Unreviewed;       376 AA.
AC   F9URK4;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   06-FEB-2013, entry version 14.
DE   SubName: Full=Phosphoribosylaminoimidazole carboxylase,ATPase subunit;
DE            EC=4.1.1.21;
GN   Name=purK1; OrderedLocusNames=lp_2728;
OS   Lactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactobacillus.
OX   NCBI_TaxID=220668;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-793 / NCIMB 8826 / WCFS1;
RX   MEDLINE=22480296; PubMed=12566566; DOI=10.1073/pnas.0337704100;
RA   Kleerebezem M., Boekhorst J., van Kranenburg R., Molenaar D.,
RA   Kuipers O.P., Leer R., Tarchini R., Peters S.A., Sandbrink H.M.,
RA   Fiers M.W., Stiekema W., Lankhorst R.M., Bron P.A., Hoffer S.M.,
RA   Groot M.N., Kerkhoven R., de Vries M., Ursing B., de Vos W.M.,
RA   Siezen R.J.;
RT   "Complete genome sequence of Lactobacillus plantarum WCFS1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:1990-1995(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=WCFS1;
RA   Siezen R.J., Francke C., Renckens B., Boekhorst J., Wels M.,
RA   Kleerebezem M., van Hijum S.A.F.T.;
RT   "Complete resequencing and reannotation of the Lactobacillus plantarum
RT   WCFS1 genome.";
RL   Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Contains 1 ATP-grasp domain.
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DR   EMBL; AL935263; CCC79843.1; -; Genomic_DNA.
DR   RefSeq; YP_004890357.1; NC_004567.2.
DR   ProteinModelPortal; F9URK4; -.
DR   GeneID; 1063026; -.
DR   KEGG; lpl:lp_2728; -.
DR   KO; K01589; -.
DR   OMA; GRKMGHF; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0048037; F:cofactor binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0004638; F:phosphoribosylaminoimidazole carboxylase activity; IEA:EC.
DR   GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.30.1490.20; ATP_grasp_subdomain_1; 1.
DR   Gene3D; 3.30.470.20; ATP_grasp_subdomain_2; 1.
DR   Gene3D; 3.40.50.20; Pre-ATP_grasp; 1.
DR   InterPro; IPR005875; AIR_COase_ATPase-su.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR003135; ATP-grasp_carboxylate-amine.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR013816; ATP_grasp_subdomain_2.
DR   InterPro; IPR006140; D-isomer_2_OHA_DH_NAD-bd.
DR   InterPro; IPR016185; PreATP-grasp_fold.
DR   InterPro; IPR011054; Rudment_hybrid_motif.
DR   Pfam; PF02826; 2-Hacid_dh_C; 1.
DR   Pfam; PF02222; ATP-grasp; 1.
DR   SUPFAM; SSF52440; PreATP-grasp-like; 1.
DR   SUPFAM; SSF51246; Rudmnt_hyb_motif; 1.
DR   TIGRFAMs; TIGR01161; purK; 1.
DR   PROSITE; PS50975; ATP_GRASP; 1.
PE   4: Predicted;
KW   ATP-binding; Complete proteome; Lyase; Nucleotide-binding;
KW   Purine biosynthesis; Reference proteome.
SQ   SEQUENCE   376 AA;  40503 MW;  FC3B974763F63621 CRC64;
     MNANFKEALL PPATIGIVGG GQLGQMMTLS AKAMGYRVGV LDPTPKAPAA QVADFQIVAA
     YDDQAALLDL ARRSDVLTYE FENVDENALI AAQAYAKLPQ GTALLHITGD RLNEKQFLHD
     HGIPVTSFAP VTDLQSLNYA LNRVGTPAIL KTAAGGYDGH GQTDLDTAVV TKAASALLTQ
     PCILEARQKF RTEVSMMVTR SAAGVVTTFP LVENQHQHHI LHTTIAPANV QPSVHSAARK
     IAVSIAESLE LRGVLGIEFF VLPDDTLLVN ELAPRPHNSG HYTIEACNIS QFEAHIRSIC
     GLPIPAITQT SPAVMRNLLG DDLTVARQQL VEHPEWHFHD YGKAAIKPQR KMGHVTVLNH
     DIDAALASLA NLKGEQ
//