ID F9URG7_LACPL Unreviewed; 494 AA. AC F9URG7; DT 19-OCT-2011, integrated into UniProtKB/TrEMBL. DT 19-OCT-2011, sequence version 1. DT 16-OCT-2013, entry version 18. DE RecName: Full=Glucose-6-phosphate 1-dehydrogenase; DE EC=1.1.1.49; GN Name=gpd; OrderedLocusNames=lp_2681; OS Lactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1). OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae; OC Lactobacillus. OX NCBI_TaxID=220668; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC BAA-793 / NCIMB 8826 / WCFS1; RX PubMed=12566566; DOI=10.1073/pnas.0337704100; RA Kleerebezem M., Boekhorst J., van Kranenburg R., Molenaar D., RA Kuipers O.P., Leer R., Tarchini R., Peters S.A., Sandbrink H.M., RA Fiers M.W.E.J., Stiekema W., Klein Lankhorst R.M., Bron P.A., RA Hoffer S.M., Nierop Groot M.N., Kerkhoven R., De Vries M., Ursing B., RA De Vos W.M., Siezen R.J.; RT "Complete genome sequence of Lactobacillus plantarum WCFS1."; RL Proc. Natl. Acad. Sci. U.S.A. 100:1990-1995(2003). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=WCFS1; RA Siezen R.J., Francke C., Renckens B., Boekhorst J., Wels M., RA Kleerebezem M., van Hijum S.A.F.T.; RT "Complete resequencing and reannotation of the Lactobacillus plantarum RT WCFS1 genome."; RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: D-glucose 6-phosphate + NADP(+) = 6-phospho-D- CC glucono-1,5-lactone + NADPH. CC -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D- CC ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): CC step 1/3. CC -!- SIMILARITY: Belongs to the glucose-6-phosphate dehydrogenase CC family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL935263; CCC79806.1; -; Genomic_DNA. DR RefSeq; YP_004890320.1; NC_004567.2. DR ProteinModelPortal; F9URG7; -. DR EnsemblBacteria; CCC79806; CCC79806; lp_2681. DR GeneID; 1062946; -. DR KEGG; lpl:lp_2681; -. DR KO; K00036; -. DR OMA; LLARDNM; -. DR UniPathway; UPA00115; UER00408. DR GO; GO:0004345; F:glucose-6-phosphate dehydrogenase activity; IEA:UniProtKB-EC. DR GO; GO:0050661; F:NADP binding; IEA:InterPro. DR GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniPathway. DR Gene3D; 3.40.50.720; -; 1. DR InterPro; IPR001282; G6P_DH. DR InterPro; IPR019796; G6P_DH_AS. DR InterPro; IPR022675; G6P_DH_C. DR InterPro; IPR022674; G6P_DH_NAD-bd. DR InterPro; IPR016040; NAD(P)-bd_dom. DR PANTHER; PTHR23429; PTHR23429; 1. DR Pfam; PF02781; G6PD_C; 1. DR Pfam; PF00479; G6PD_N; 1. DR PIRSF; PIRSF000110; G6PD; 1. DR PRINTS; PR00079; G6PDHDRGNASE. DR TIGRFAMs; TIGR00871; zwf; 1. DR PROSITE; PS00069; G6P_DEHYDROGENASE; 1. PE 3: Inferred from homology; KW Carbohydrate metabolism; Complete proteome; Glucose metabolism; NADP; KW Oxidoreductase; Reference proteome. SQ SEQUENCE 494 AA; 56786 MW; 46018F265C3BFA56 CRC64; MSNEKIALFT IFGGTGDLAQ RKLYPSLFKL YQKGYLKDHF AVIGTARRPW TDDHYHEVIS DSLADLNADQ ETVTQFASHF YYQSHDVTDA EHYRTLKKLS EKLDAQYGLQ GNRIFYLAMA PNFFGTIAQH LRSENILTDN GFNRVIIEKP FGHDYESAKE LNDQLTATFN ENQIYRIDHY LGKEMIQNIT AIRFGNNIWE SLWNNRYIDN VQITLSEKLG VEERAVYYDN SGALRDMVQN HILQILSLLT MDQPVEFTEN DIDVEKVKAL RSLRPLKPEE VATNFVRGQY GAGDDAKAYR DEDKISSDSN TDTFVAGKVM IDNYRWSGVP FYIRTGKRLA DKFTRIDVVF KRPVVNIFNH EDVRANDDAA TSLDPNILTI NVEPTEGFEL RMNAKAIGQG FATTPVKLNY SHDAEATAGS PEAYERLLHD ALNGDATNFT HWQEVADSWK FVDVIQKYWD EHQPEFPNYR PGTMGPDAAD ELLRQDGHRW VYRN //