ID F8U419_ADEBA Unreviewed; 190 AA. AC F8U419; DT 21-SEP-2011, integrated into UniProtKB/TrEMBL. DT 21-SEP-2011, sequence version 1. DT 03-MAY-2023, entry version 28. DE RecName: Full=Hexon protein {ECO:0000256|ARBA:ARBA00019716}; DE AltName: Full=Protein II {ECO:0000256|ARBA:ARBA00032254}; DE Flags: Fragment; OS Bovine adenovirus C serotype 10 (BAdV-10) (Mastadenovirus bos10). OC Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes; OC Rowavirales; Adenoviridae; Mastadenovirus; Bovine mastadenovirus C. OX NCBI_TaxID=39788 {ECO:0000313|EMBL:AEH05597.1}; OH NCBI_TaxID=9913; Bos taurus (Bovine). RN [1] {ECO:0000313|EMBL:AEH05597.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Ma7 {ECO:0000313|EMBL:AEH05597.1}; RX PubMed=21622778; DOI=10.1128/AEM.00625-11; RA Sibley S.D., Goldberg T.L., Pedersen J.A.; RT "Detection of known and novel adenoviruses in cattle wastes via broad- RT spectrum primers."; RL Appl. Environ. Microbiol. 77:5001-5008(2011). CC -!- FUNCTION: Major capsid protein that self-associates to form 240 hexon CC trimers, each in the shape of a hexagon, building most of the pseudo CC T=25 capsid. Assembled into trimeric units with the help of the CC chaperone shutoff protein. Transported by pre-protein VI to the nucleus CC where it associates with other structural proteins to form an empty CC capsid. Might be involved, through its interaction with host dyneins, CC in the intracellular microtubule-dependent transport of incoming viral CC capsid to the nucleus. {ECO:0000256|ARBA:ARBA00024662}. CC -!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000256|ARBA:ARBA00004147}. CC Virion {ECO:0000256|ARBA:ARBA00004328}. CC -!- SIMILARITY: Belongs to the adenoviridae hexon protein family. CC {ECO:0000256|ARBA:ARBA00008659}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JF699112; AEH05597.1; -; Genomic_DNA. DR GO; GO:0039623; C:T=25 icosahedral viral capsid; IEA:UniProtKB-KW. DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW. DR Gene3D; 3.90.249.10; Hexon Major Viral Coat Protein, domain 3; 1. DR InterPro; IPR016107; Adenovirus_Pll_hexon_N. DR InterPro; IPR016110; Adenovirus_Pll_hexon_sub3. DR InterPro; IPR016112; VP_dsDNA_II. DR Pfam; PF01065; Adeno_hexon; 1. DR SUPFAM; SSF49749; Group II dsDNA viruses VP; 1. PE 3: Inferred from homology; KW Capsid protein {ECO:0000256|ARBA:ARBA00022561}; KW Host-virus interaction {ECO:0000256|ARBA:ARBA00022581}; KW T=25 icosahedral capsid protein {ECO:0000256|ARBA:ARBA00023275}; KW Virion {ECO:0000256|ARBA:ARBA00022844}; KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}. FT DOMAIN 1..163 FT /note="Adenovirus Pll hexon N-terminal" FT /evidence="ECO:0000259|Pfam:PF01065" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:AEH05597.1" FT NON_TER 190 FT /evidence="ECO:0000313|EMBL:AEH05597.1" SQ SEQUENCE 190 AA; 21290 MW; 75A21479FDDA7A2E CRC64; ASEYLSAGLV QFARATDSYF SLGNKFRNPT VAPTHDVTTE RSQRLQLRFV PVDKEDTQYT YKTRFQLTVG DNRVLDMGST YFDIRGVIDR GPSFKPYSGT AYNNLAPRSA PNNCFFKNDN GGHPDVAYAQ LPFVGTREQQ NLMVLNAEGQ RVAADPIYQP EPQYGVDAWP QNRLGDFNAG RALKSDVTHL //