ID F7AYZ6_MOUSE Unreviewed; 81 AA. AC F7AYZ6; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 27-JUL-2011, sequence version 1. DT 12-AUG-2020, entry version 49. DE SubName: Full=Sodium- and chloride-dependent betaine transporter {ECO:0000313|Ensembl:ENSMUSP00000130715}; DE Flags: Fragment; GN Name=Slc6a12 {ECO:0000313|Ensembl:ENSMUSP00000130715, GN ECO:0000313|MGI:MGI:95628}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000130715, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000130715, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000130715, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000130715} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000130715}; RG Ensembl; RL Submitted (JUN-2011) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi- CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC153982; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR SMR; F7AYZ6; -. DR PRIDE; F7AYZ6; -. DR Antibodypedia; 22038; 144 antibodies. DR Ensembl; ENSMUST00000165456; ENSMUSP00000130715; ENSMUSG00000030109. DR MGI; MGI:95628; Slc6a12. DR GeneTree; ENSGT00940000161075; -. DR HOGENOM; CLU_2580050_0_0_1; -. DR Proteomes; UP000000589; Chromosome 6. DR Bgee; ENSMUSG00000030109; Expressed in decidua and 80 other tissues. DR ExpressionAtlas; F7AYZ6; baseline and differential. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW. DR InterPro; IPR000175; Na/ntran_symport. DR InterPro; IPR037272; SNS_sf. DR PANTHER; PTHR11616; PTHR11616; 1. DR Pfam; PF00209; SNF; 1. DR SUPFAM; SSF161070; SSF161070; 1. DR PROSITE; PS50267; NA_NEUROTRAN_SYMP_3; 1. PE 4: Predicted; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Symport {ECO:0000256|ARBA:ARBA00022847}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}. FT TRANSMEM 12..34 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT NON_TER 1 FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000130715" SQ SEQUENCE 81 AA; 9180 MW; 7671D831BFB45079 CRC64; VVYFTATFPY LMLIILLIRG VTLPGAYQGI VFYLKPDLLR LKDPQGLHRP LLPEQCYQLR GWVCCLLHLG LHVSGAGNTH F //