ID F7AYZ6_MOUSE Unreviewed; 81 AA. AC F7AYZ6; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 27-JUL-2011, sequence version 1. DT 17-JUN-2020, entry version 48. DE SubName: Full=Sodium- and chloride-dependent betaine transporter {ECO:0000313|Ensembl:ENSMUSP00000130715}; DE Flags: Fragment; GN Name=Slc6a12 {ECO:0000313|Ensembl:ENSMUSP00000130715, GN ECO:0000313|MGI:MGI:95628}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000130715, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000130715, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000130715, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000130715} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000130715}; RG Ensembl; RL Submitted (JUN-2011) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC153982; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR SMR; F7AYZ6; -. DR PRIDE; F7AYZ6; -. DR Antibodypedia; 22038; 141 antibodies. DR Ensembl; ENSMUST00000165456; ENSMUSP00000130715; ENSMUSG00000030109. DR MGI; MGI:95628; Slc6a12. DR eggNOG; KOG3659; Eukaryota. DR eggNOG; COG0733; LUCA. DR GeneTree; ENSGT00940000161075; -. DR HOGENOM; CLU_2580050_0_0_1; -. DR Proteomes; UP000000589; Chromosome 6. DR Bgee; ENSMUSG00000030109; Expressed in decidua and 48 other tissues. DR ExpressionAtlas; F7AYZ6; baseline and differential. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. DR InterPro; IPR000175; Na/ntran_symport. DR InterPro; IPR037272; SNS_sf. DR PANTHER; PTHR11616; PTHR11616; 1. DR Pfam; PF00209; SNF; 1. DR SUPFAM; SSF161070; SSF161070; 1. DR PROSITE; PS50267; NA_NEUROTRAN_SYMP_3; 1. PE 4: Predicted; KW Membrane {ECO:0000256|SAAS:SAAS00943582, ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Symport {ECO:0000256|SAAS:SAAS00943603}; KW Transmembrane {ECO:0000256|SAAS:SAAS00943611, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAAS:SAAS00943634, KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00943587}. FT TRANSMEM 12..34 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT NON_TER 1 FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000130715" SQ SEQUENCE 81 AA; 9180 MW; 7671D831BFB45079 CRC64; VVYFTATFPY LMLIILLIRG VTLPGAYQGI VFYLKPDLLR LKDPQGLHRP LLPEQCYQLR GWVCCLLHLG LHVSGAGNTH F //