ID F6XU19_MOUSE Unreviewed; 13 AA. AC F6XU19; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 27-JUL-2011, sequence version 1. DT 28-MAR-2018, entry version 38. DE SubName: Full=Prolow-density lipoprotein receptor-related protein 1 {ECO:0000313|Ensembl:ENSMUSP00000120567}; DE Flags: Fragment; GN Name=Lrp1 {ECO:0000313|Ensembl:ENSMUSP00000120567, GN ECO:0000313|MGI:MGI:96828}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000120567, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000120567, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000120567, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000120567} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000120567}; RG Ensembl; RL Submitted (JUN-2011) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC160970; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC167719; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSMUST00000129727; ENSMUSP00000120567; ENSMUSG00000040249. DR MGI; MGI:96828; Lrp1. DR GeneTree; ENSGT00760000118968; -. DR Reactome; R-MMU-2168880; Scavenging of heme from plasma. DR Reactome; R-MMU-975634; Retinoid metabolism and transport. DR Proteomes; UP000000589; Chromosome 10. DR Bgee; ENSMUSG00000040249; -. DR ExpressionAtlas; F6XU19; baseline and differential. DR GO; GO:0016323; C:basolateral plasma membrane; IEA:Ensembl. DR GO; GO:0005769; C:early endosome; IEA:Ensembl. DR GO; GO:0043235; C:receptor complex; IEA:Ensembl. DR GO; GO:0016964; F:alpha-2 macroglobulin receptor activity; IEA:Ensembl. DR GO; GO:0034185; F:apolipoprotein binding; IEA:Ensembl. DR GO; GO:0032050; F:clathrin heavy chain binding; IEA:Ensembl. DR GO; GO:0032403; F:protein complex binding; IEA:Ensembl. DR GO; GO:0097242; P:amyloid-beta clearance; IEA:Ensembl. DR GO; GO:0002265; P:astrocyte activation involved in immune response; IEA:Ensembl. DR GO; GO:1904646; P:cellular response to amyloid-beta; IEA:Ensembl. DR GO; GO:1900223; P:positive regulation of amyloid-beta clearance; IEA:Ensembl. DR GO; GO:0010942; P:positive regulation of cell death; IEA:Ensembl. DR GO; GO:0045807; P:positive regulation of endocytosis; IEA:Ensembl. DR GO; GO:1905167; P:positive regulation of lysosomal protein catabolic process; IEA:Ensembl. DR GO; GO:0032092; P:positive regulation of protein binding; IEA:Ensembl. DR GO; GO:1903078; P:positive regulation of protein localization to plasma membrane; IEA:Ensembl. DR GO; GO:0045056; P:transcytosis; IEA:Ensembl. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT NON_TER 1 1 {ECO:0000313|Ensembl:ENSMUSP00000120567}. SQ SEQUENCE 13 AA; 1513 MW; 07EAE1ED301FB054 CRC64; EECDSNICRP LHP //