ID F6WX44_HORSE Unreviewed; 325 AA. AC F6WX44; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 13-SEP-2023, sequence version 2. DT 02-OCT-2024, entry version 65. DE SubName: Full=C1GALT1 specific chaperone 1 {ECO:0000313|Ensembl:ENSECAP00000002771.2}; GN Name=C1GALT1C1 {ECO:0000313|Ensembl:ENSECAP00000002771.2, GN ECO:0000313|VGNC:VGNC:15935}; OS Equus caballus (Horse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000002771.2, ECO:0000313|Proteomes:UP000002281}; RN [1] {ECO:0000313|Ensembl:ENSECAP00000002771.2, ECO:0000313|Proteomes:UP000002281} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000002771.2, RC ECO:0000313|Proteomes:UP000002281}; RX PubMed=19892987; DOI=10.1126/science.1178158; RG Broad Institute Genome Sequencing Platform; RG Broad Institute Whole Genome Assembly Team; RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F., RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O., RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T., RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T., RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S., RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G., RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R., RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A., RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J., RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.; RT "Genome sequence, comparative analysis, and population genetics of the RT domestic horse."; RL Science 326:865-867(2009). RN [2] {ECO:0000313|Ensembl:ENSECAP00000002771.2} RP IDENTIFICATION. RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000002771.2}; RG Ensembl; RL Submitted (JUN-2024) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single- CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}. CC -!- SIMILARITY: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T CC subfamily. {ECO:0000256|ARBA:ARBA00006462}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR AlphaFoldDB; F6WX44; -. DR STRING; 9796.ENSECAP00000002771; -. DR PaxDb; 9796-ENSECAP00000002771; -. DR Ensembl; ENSECAT00000004004.3; ENSECAP00000002771.2; ENSECAG00000004034.3. DR VGNC; VGNC:15935; C1GALT1C1. DR GeneTree; ENSGT00940000155145; -. DR HOGENOM; CLU_874237_0_0_1; -. DR InParanoid; F6WX44; -. DR OMA; WVMMRKA; -. DR OrthoDB; 3534522at2759; -. DR TreeFam; TF317293; -. DR Proteomes; UP000002281; Chromosome X. DR Bgee; ENSECAG00000004034; Expressed in endometrium and 23 other cell types or tissues. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell. DR GO; GO:0016263; F:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity; IBA:GO_Central. DR GO; GO:0030168; P:platelet activation; IEA:Ensembl. DR GO; GO:0036344; P:platelet morphogenesis; IEA:Ensembl. DR GO; GO:0006493; P:protein O-linked glycosylation; IEA:Ensembl. DR Gene3D; 3.90.550.50; -; 1. DR InterPro; IPR026050; C1GALT1/C1GALT1_chp1. DR PANTHER; PTHR23033; BETA1,3-GALACTOSYLTRANSFERASE; 1. DR PANTHER; PTHR23033:SF2; C1GALT1-SPECIFIC CHAPERONE 1; 1. PE 3: Inferred from homology; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000002281}; KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}. FT TRANSMEM 15..35 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" SQ SEQUENCE 325 AA; 37386 MW; F4AF7EF305F6DB08 CRC64; MLREKWKMLS ESSSFLKGVM LGSIFCALIT ILGHVRIGYG SRMYHHEHHH LQAPNKEDIL KISEDERMEL SKSFRVYCII LVKPKDVSLW AAVKETWTKH CDKAEFFSSE NVKVFKSINM ETNDMWLMMR KAYKYAFDNY RNQYNWFFLA RPTTFAIIEN LKYFLLKKDP SQPFYLGHTV KSGDLEYVSV EGGIVLSIES MKRLNHLLSI PEKCPEQGGM IWKISEDKQL AVCLKYAGVL AENAEDSEGK DVFNTKSVGL FIKEAMTNHP NLVVEGCCSD MAVTFNGLTP NQMHVMMYGV YRLRAFGHVF NDALVFLPPN VSDND //