ID F6V6F0_MOUSE Unreviewed; 119 AA. AC F6V6F0; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 27-JUL-2011, sequence version 1. DT 24-JUL-2024, entry version 74. DE SubName: Full=Centromere protein F {ECO:0000313|Ensembl:ENSMUSP00000132430.2}; DE Flags: Fragment; GN Name=Cenpf {ECO:0000313|Ensembl:ENSMUSP00000132430.2, GN ECO:0000313|MGI:MGI:1313302}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000132430.2, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000132430.2} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000132430.2}; RG Ensembl; RL Submitted (APR-2024) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR jPOST; F6V6F0; -. DR PeptideAtlas; F6V6F0; -. DR ProteomicsDB; 369460; -. DR Antibodypedia; 4038; 296 antibodies from 35 providers. DR Ensembl; ENSMUST00000165798.2; ENSMUSP00000132430.2; ENSMUSG00000026605.15. DR AGR; MGI:1313302; -. DR MGI; MGI:1313302; Cenpf. DR VEuPathDB; HostDB:ENSMUSG00000026605; -. DR GeneTree; ENSGT00730000111187; -. DR HOGENOM; CLU_2078416_0_0_1; -. DR ChiTaRS; Cenpf; mouse. DR Proteomes; UP000000589; Chromosome 1. DR Bgee; ENSMUSG00000026605; Expressed in animal zygote and 185 other cell types or tissues. DR ExpressionAtlas; F6V6F0; baseline and differential. DR GO; GO:0005930; C:axoneme; IDA:MGI. DR GO; GO:0005813; C:centrosome; IDA:MGI. DR GO; GO:0000775; C:chromosome, centromeric region; ISO:MGI. DR GO; GO:0036064; C:ciliary basal body; IDA:MGI. DR GO; GO:0097539; C:ciliary transition fiber; IDA:MGI. DR GO; GO:0005634; C:nucleus; IDA:MGI. DR GO; GO:0045120; C:pronucleus; IDA:MGI. DR GO; GO:0000922; C:spindle pole; IBA:GO_Central. DR GO; GO:0070840; F:dynein complex binding; IBA:GO_Central. DR GO; GO:0008017; F:microtubule binding; IEA:InterPro. DR GO; GO:0051310; P:metaphase chromosome alignment; IBA:GO_Central. DR GO; GO:0000278; P:mitotic cell cycle; IBA:GO_Central. DR GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IBA:GO_Central. DR GO; GO:0016202; P:regulation of striated muscle tissue development; IDA:MGI. DR InterPro; IPR043513; Cenp-F. DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd. DR PANTHER; PTHR18874:SF10; CENTROMERE PROTEIN F; 1. DR PANTHER; PTHR18874; CMF/LEK/CENP CELL DIVISION-RELATED; 1. DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1. PE 1: Evidence at protein level; KW Proteomics identification {ECO:0007829|ProteomicsDB:F6V6F0}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT DOMAIN 25..50 FT /note="Kinetochore protein Cenp-F/LEK1 Rb protein-binding" FT /evidence="ECO:0000259|Pfam:PF10490" FT REGION 1..119 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 1..28 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 36..119 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 1 FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000132430.2" FT NON_TER 119 FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000132430.2" SQ SEQUENCE 119 AA; 12390 MW; 2562D78C78F71CB8 CRC64; XIPGPSPNTS VSEMKSASGQ NKASGFADIP TGKTSPYILR RTTMATRTSP RFATQKLVGS SPSLGKENVV ESSKPTAGGS RSQKVKVVQE SSADSHTAFQ ELPAKSLTAS NIPGRNSTE //