ID F6V6F0_MOUSE Unreviewed; 119 AA. AC F6V6F0; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 27-JUL-2011, sequence version 1. DT 27-MAR-2024, entry version 72. DE SubName: Full=Centromere protein F {ECO:0000313|Ensembl:ENSMUSP00000132430.2}; DE Flags: Fragment; GN Name=Cenpf {ECO:0000313|Ensembl:ENSMUSP00000132430.2, GN ECO:0000313|MGI:MGI:1313302}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000132430.2, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000132430.2, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000132430.2, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000132430.2} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000132430.2}; RG Ensembl; RL Submitted (NOV-2023) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR jPOST; F6V6F0; -. DR MaxQB; F6V6F0; -. DR PeptideAtlas; F6V6F0; -. DR ProteomicsDB; 369460; -. DR Antibodypedia; 4038; 311 antibodies from 34 providers. DR Ensembl; ENSMUST00000165798.2; ENSMUSP00000132430.2; ENSMUSG00000026605.15. DR AGR; MGI:1313302; -. DR MGI; MGI:1313302; Cenpf. DR VEuPathDB; HostDB:ENSMUSG00000026605; -. DR GeneTree; ENSGT00730000111187; -. DR HOGENOM; CLU_2078416_0_0_1; -. DR ChiTaRS; Cenpf; mouse. DR Proteomes; UP000000589; Chromosome 1. DR Bgee; ENSMUSG00000026605; Expressed in animal zygote and 185 other cell types or tissues. DR ExpressionAtlas; F6V6F0; baseline and differential. DR GO; GO:0005930; C:axoneme; IDA:MGI. DR GO; GO:0005813; C:centrosome; IDA:MGI. DR GO; GO:0000775; C:chromosome, centromeric region; ISO:MGI. DR GO; GO:0036064; C:ciliary basal body; IDA:MGI. DR GO; GO:0097539; C:ciliary transition fiber; IDA:MGI. DR GO; GO:0005737; C:cytoplasm; ISO:MGI. DR GO; GO:0005829; C:cytosol; ISO:MGI. DR GO; GO:0030496; C:midbody; ISO:MGI. DR GO; GO:0005635; C:nuclear envelope; ISO:MGI. DR GO; GO:0016363; C:nuclear matrix; ISO:MGI. DR GO; GO:0031965; C:nuclear membrane; ISO:MGI. DR GO; GO:0005654; C:nucleoplasm; ISO:MGI. DR GO; GO:0005634; C:nucleus; IDA:MGI. DR GO; GO:0000940; C:outer kinetochore; ISO:MGI. DR GO; GO:0045120; C:pronucleus; IDA:MGI. DR GO; GO:0005819; C:spindle; ISO:MGI. DR GO; GO:0000922; C:spindle pole; ISO:MGI. DR GO; GO:0140297; F:DNA-binding transcription factor binding; ISO:MGI. DR GO; GO:0070840; F:dynein complex binding; ISO:MGI. DR GO; GO:0008017; F:microtubule binding; IEA:InterPro. DR GO; GO:0042803; F:protein homodimerization activity; ISO:MGI. DR GO; GO:0007059; P:chromosome segregation; ISO:MGI. DR GO; GO:0001822; P:kidney development; ISO:MGI. DR GO; GO:0051310; P:metaphase chromosome alignment; ISO:MGI. DR GO; GO:0000278; P:mitotic cell cycle; ISO:MGI. DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; ISO:MGI. DR GO; GO:0015031; P:protein transport; ISO:MGI. DR GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; ISO:MGI. DR GO; GO:0016202; P:regulation of striated muscle tissue development; IDA:MGI. DR GO; GO:0021591; P:ventricular system development; ISO:MGI. DR InterPro; IPR043513; Cenp-F. DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd. DR PANTHER; PTHR18874:SF10; CENTROMERE PROTEIN F; 1. DR PANTHER; PTHR18874; CMF/LEK/CENP CELL DIVISION-RELATED; 1. DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1. PE 1: Evidence at protein level; KW Proteomics identification {ECO:0007829|EPD:F6V6F0, KW ECO:0007829|MaxQB:F6V6F0}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT DOMAIN 25..50 FT /note="Kinetochore protein Cenp-F/LEK1 Rb protein-binding" FT /evidence="ECO:0000259|Pfam:PF10490" FT REGION 1..119 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 1..28 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 36..119 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 1 FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000132430.2" FT NON_TER 119 FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000132430.2" SQ SEQUENCE 119 AA; 12390 MW; 2562D78C78F71CB8 CRC64; XIPGPSPNTS VSEMKSASGQ NKASGFADIP TGKTSPYILR RTTMATRTSP RFATQKLVGS SPSLGKENVV ESSKPTAGGS RSQKVKVVQE SSADSHTAFQ ELPAKSLTAS NIPGRNSTE //