ID F6V0D3_MONDO Unreviewed; 184 AA. AC F6V0D3; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 27-JUL-2011, sequence version 1. DT 03-APR-2013, entry version 9. DE SubName: Full=Uncharacterized protein; GN Name=GREM1; OS Monodelphis domestica (Gray short-tailed opossum). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis. OX NCBI_TaxID=13616; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=17495919; DOI=10.1038/nature05805; RA Mikkelsen T.S., Wakefield M.J., Aken B., Amemiya C.T., Chang J.L., RA Duke S., Garber M., Gentles A.J., Goodstadt L., Heger A., Jurka J., RA Kamal M., Mauceli E., Searle S.M., Sharpe T., Baker M.L., Batzer M.A., RA Benos P.V., Belov K., Clamp M., Cook A., Cuff J., Das R., Davidow L., RA Deakin J.E., Fazzari M.J., Glass J.L., Grabherr M., Greally J.M., RA Gu W., Hore T.A., Huttley G.A., Kleber M., Jirtle R.L., Koina E., RA Lee J.T., Mahony S., Marra M.A., Miller R.D., Nicholls R.D., Oda M., RA Papenfuss A.T., Parra Z.E., Pollock D.D., Ray D.A., Schein J.E., RA Speed T.P., Thompson K., VandeBerg J.L., Wade C.M., Walker J.A., RA Waters P.D., Webber C., Weidman J.R., Xie X., Zody M.C., Baldwin J., RA Abdouelleil A., Abdulkadir J., Abebe A., Abera B., Abreu J., RA Acer S.C., Aftuck L., Alexander A., An P., Anderson E., Anderson S., RA Arachi H., Azer M., Bachantsang P., Barry A., Bayul T., Berlin A., RA Bessette D., Bloom T., Bloom T., Boguslavskiy L., Bonnet C., RA Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S., RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., RA Costello M., D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., RA Dhargay N., Dooley K., Dooley E., Doricent M., Dorje P., Dorjee K., RA Dupes A., Elong R., Falk J., Farina A., Faro S., Ferguson D., RA Fisher S., Foley C.D., Franke A., Friedrich D., Gadbois L., Gearin G., RA Gearin C.R., Giannoukos G., Goode T., Graham J., Grandbois E., RA Grewal S., Gyaltsen K., Hafez N., Hagos B., Hall J., Henson C., RA Hollinger A., Honan T., Huard M.D., Hughes L., Hurhula B., Husby M.E., RA Kamat A., Kanga B., Kashin S., Khazanovich D., Kisner P., Lance K., RA Lara M., Lee W., Lennon N., Letendre F., LeVine R., Lipovsky A., RA Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y., Lubonja R., RA Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C., RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O., RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., RA Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., RA Nicol R., Norbu C., Norbu N., Novod N., O'Neill B., Osman S., RA Markiewicz E., Oyono O.L., Patti C., Phunkhang P., Pierre F., RA Priest M., Raghuraman S., Rege F., Reyes R., Rise C., Rogov P., RA Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L., Shih D., RA Sparrow T., Spaulding J., Stalker J., Stange-Thomann N., RA Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T., RA Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T., RA Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J., RA Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A., RA Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C., RA Gnerre S., MacCallum I., Graves J.A., Ponting C.P., Breen M., RA Samollow P.B., Lander E.S., Lindblad-Toh K.; RT "Genome of the marsupial Monodelphis domestica reveals innovation in RT non-coding sequences."; RL Nature 447:167-177(2007). RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; XP_001380822.2; XM_001380785.2. DR Ensembl; ENSMODT00000001764; ENSMODP00000033697; ENSMODG00000001426. DR GeneID; 100031599; -. DR KEGG; mdo:100031599; -. DR GeneTree; ENSGT00510000046909; -. DR OMA; NDSEQTE; -. DR GO; GO:0009986; C:cell surface; IEA:Compara. DR GO; GO:0005615; C:extracellular space; IEA:Compara. DR GO; GO:0030296; F:protein tyrosine kinase activator activity; IEA:Compara. DR GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Compara. DR GO; GO:0002042; P:cell migration involved in sprouting angiogenesis; IEA:Compara. DR GO; GO:0007267; P:cell-cell signaling; IEA:Compara. DR GO; GO:0030199; P:collagen fibril organization; IEA:Compara. DR GO; GO:0048263; P:determination of dorsal identity; IEA:Compara. DR GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Compara. DR GO; GO:0003337; P:mesenchymal to epithelial transition involved in metanephros morphogenesis; IEA:Compara. DR GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:Compara. DR GO; GO:1900158; P:negative regulation of bone mineralization involved in bone maturation; IEA:Compara. DR GO; GO:0046851; P:negative regulation of bone remodeling; IEA:Compara. DR GO; GO:1900155; P:negative regulation of bone trabecula formation; IEA:Compara. DR GO; GO:0090191; P:negative regulation of branching involved in ureteric bud morphogenesis; IEA:Compara. DR GO; GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IEA:Compara. DR GO; GO:0033689; P:negative regulation of osteoblast proliferation; IEA:Compara. DR GO; GO:0090291; P:negative regulation of osteoclast proliferation; IEA:Compara. DR GO; GO:0060394; P:negative regulation of pathway-restricted SMAD protein phosphorylation; IEA:Compara. DR GO; GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:Compara. DR GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Compara. DR GO; GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; IEA:Compara. DR GO; GO:2000727; P:positive regulation of cardiac muscle cell differentiation; IEA:Compara. DR GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Compara. DR GO; GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IEA:Compara. DR GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IEA:Compara. DR GO; GO:1900086; P:positive regulation of peptidyl-tyrosine autophosphorylation; IEA:Compara. DR GO; GO:0002092; P:positive regulation of receptor internalization; IEA:Compara. DR GO; GO:0051973; P:positive regulation of telomerase activity; IEA:Compara. DR GO; GO:0003257; P:positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation; IEA:Compara. DR GO; GO:0009954; P:proximal/distal pattern formation; IEA:Compara. DR GO; GO:0010717; P:regulation of epithelial to mesenchymal transition; IEA:Compara. DR GO; GO:0051893; P:regulation of focal adhesion assembly; IEA:Compara. DR GO; GO:0007165; P:signal transduction; IEA:GOC. DR GO; GO:0060676; P:ureteric bud formation; IEA:Compara. DR InterPro; IPR006207; Cys_knot_C. DR InterPro; IPR004133; DAN. DR InterPro; IPR017159; Gremlin_precursor. DR Pfam; PF03045; DAN; 1. DR PIRSF; PIRSF037254; Gremlin_precursor; 1. DR SMART; SM00041; CT; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 184 AA; 20771 MW; CAD7128B604A4517 CRC64; MGRTAYTVGA LLLLLGTLLS ATEGKKKGSQ GAIPPPDKDQ YNDSEQTQTP QQPGSRNRGR GQGRGTAMPG EEVLESSQEA LHVTERKYLK RDWCKTQPLK QTIHEEGCNS RTIINRFCYG QCNSFYIPRH IRKEEGSFQS CSFCKPKKFT TMMVTLNCPE LQPPTKKKRV TRVKQCRCIS IDLD //