ID F6TJZ1_XENTR Unreviewed; 971 AA. AC F6TJZ1; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 11-DEC-2019, sequence version 2. DT 11-DEC-2019, entry version 37. DE RecName: Full=Anti_prolifrtn domain-containing protein {ECO:0000259|PROSITE:PS00960}; GN Name=ptk2b {ECO:0000313|Ensembl:ENSXETP00000008843}; OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana. OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000008843, ECO:0000313|Proteomes:UP000008143}; RN [1] {ECO:0000313|Ensembl:ENSXETP00000008843} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000008843}; RX PubMed=20431018; DOI=10.1126/science.1183670; RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J., RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L., RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R., RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J., RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H., RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K., RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A., RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T., RA Khokha M.K., Richardson P.M., Rokhsar D.S.; RT "The genome of the Western clawed frog Xenopus tropicalis."; RL Science 328:633-636(2010). RN [2] {ECO:0000313|Ensembl:ENSXETP00000008843} RP IDENTIFICATION. RG Ensembl; RL Submitted (JUN-2011) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR STRING; 8364.ENSXETP00000008843; -. DR PaxDb; F6TJZ1; -. DR Ensembl; ENSXETT00000034288; ENSXETP00000008843; ENSXETG00000011894. DR eggNOG; KOG4006; Eukaryota. DR eggNOG; ENOG410ZZC0; LUCA. DR GeneTree; ENSGT00940000157269; -. DR InParanoid; F6TJZ1; -. DR TreeFam; TF105272; -. DR Proteomes; UP000008143; Unassembled WGS sequence. DR Bgee; ENSXETG00000004087; Expressed in 8 organ(s), highest expression level in gastrula. DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central. DR GO; GO:0005634; C:nucleus; IBA:GO_Central. DR GO; GO:0008285; P:negative regulation of cell population proliferation; IBA:GO_Central. DR GO; GO:0045930; P:negative regulation of mitotic cell cycle; IBA:GO_Central. DR Gene3D; 1.20.120.1120; -; 1. DR InterPro; IPR002087; Anti_prolifrtn. DR InterPro; IPR036054; BTG-like_sf. DR Pfam; PF07742; BTG; 1. DR PRINTS; PR00310; ANTIPRLFBTG1. DR SMART; SM00099; btg1; 1. DR SUPFAM; SSF160696; SSF160696; 1. DR PROSITE; PS00960; BTG_1; 1. PE 4: Predicted; KW Reference proteome {ECO:0000313|Proteomes:UP000008143}. SQ SEQUENCE 971 AA; 111233 MW; 5712E84734B020EB CRC64; MSLDHANRTK GGTFNRPDGP AEVPAEVEIS KEEMRILKVC FHSNSSNLVK NFKLVKCSIY TDIQEIISSI LLSGRIGPDI KHVECYGLRL KHLKSDEIHW LHPELTVGEV QEKYECLHLE AEWRYDLRIR YLPEDFNESF KKDKTTLLYF YQQLRNDYMQ QYATKVSEGM ALQLGCLELR RFYKDMPQNA LEKKSNFEFL EKEVGLDLFF PKQMQESLKP KQFRKMIQQT FQQYGSLKEE ECITRFMNTL STFTSIDQET YRCELAQGWS ITVDLVIGPK GIRQLTTKDS KPTCFAEFKQ IKSIKCSLLE DGWALLLLGI SGAPQPLAIK TSSLAVAENM ADLIDGYCRL QNESKDSLIV NPKKGENLPE LGKRALLQDS DIYAEIPESG WRATDNRFTI SRSDVALGRI LGEGFFGEVY DGVYVKPKGD KINVAVKTCK NDCAADVKEK FMSEAYLMRN LDHPHIVKLI GIIEDDPIWI VMELYPYGEL GQYLEKNKNS LQVLSLILYS LQICKALAYL EGINCVHRDI AVRNILVASP ECVKLGDFGL SRYLEEEEYY KASVTRLPIK WMAPESINFR RFTSASDVWM FGVCMWEILS FGKQPFFWLE NKDVISVIEK GDRLPKPEMC PPTLYTLMTR CWTYDPFERP KFTELVCSLS DIYQTEKEII KDKERNNRQR PPKIIEPPPM QEPPPKVSRR SFSTLPVSVL LCSLTAQVPE SLCASSPTLC SPTDYQSPLD STRSPPLPRH SIFKRRSMRE EDFVKPNSKE EAQKLWEKER DKMLQVLNRQ QQQMEEDGKW LKQEEKSLAN TLKVSHTSPS FLTNPLFLFF VAEFTVPPQK PPRLGAQPTP TANIDRTDDG VYQSVMELVK AVLQLKNDIY QLPPEGYVAV VKVRERIPAT IEGTQKLLSK DLAELINKMR LAQQNAVTSL SEECKKQMLT ASHTMAVDAK NLLDAVDQAR VRANLAKVAA E //