ID F6SUV7_MOUSE Unreviewed; 957 AA. AC F6SUV7; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 27-JUL-2011, sequence version 1. DT 16-SEP-2015, entry version 32. DE SubName: Full=TBC1 domain family member 4 {ECO:0000313|Ensembl:ENSMUSP00000124511}; DE Flags: Fragment; GN Name=Tbc1d4 {ECO:0000313|Ensembl:ENSMUSP00000124511, GN ECO:0000313|MGI:MGI:2429660}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000124511, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000124511, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000124511, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000213|PubMed:21183079} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001; RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.; RT "A tissue-specific atlas of mouse protein phosphorylation and RT expression."; RL Cell 143:1174-1189(2010). RN [3] {ECO:0000313|Ensembl:ENSMUSP00000124511} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000124511}; RG Ensembl; RL Submitted (JUN-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000124511}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CT025630; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; CT573019; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; CT573033; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR STRING; 10090.ENSMUSP00000125509; -. DR Ensembl; ENSMUST00000159951; ENSMUSP00000124511; ENSMUSG00000033083. DR MGI; MGI:2429660; Tbc1d4. DR GeneTree; ENSGT00750000117238; -. DR NextBio; 35557092; -. DR Proteomes; UP000000589; Chromosome 14. DR ExpressionAtlas; F6SUV7; baseline and differential. DR GO; GO:0005737; C:cytoplasm; ISO:MGI. DR GO; GO:0070062; C:extracellular exosome; ISO:MGI. DR GO; GO:0032869; P:cellular response to insulin stimulus; ISO:MGI. DR GO; GO:0016192; P:vesicle-mediated transport; ISO:MGI. DR Gene3D; 2.30.29.30; -; 1. DR InterPro; IPR021785; DUF3350. DR InterPro; IPR011993; PH/PTB_dom. DR InterPro; IPR006020; PTB/PI_dom. DR InterPro; IPR000195; Rab-GTPase-TBC_dom. DR Pfam; PF11830; DUF3350; 1. DR Pfam; PF00640; PID; 1. DR Pfam; PF00566; RabGAP-TBC; 1. DR SMART; SM00462; PTB; 1. DR SMART; SM00164; TBC; 1. DR SUPFAM; SSF47923; SSF47923; 2. DR PROSITE; PS01179; PID; 1. DR PROSITE; PS50086; TBC_RABGAP; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Proteomics identification {ECO:0000213|MaxQB:F6SUV7, KW ECO:0000213|PeptideAtlas:F6SUV7}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT NON_TER 1 1 {ECO:0000313|Ensembl:ENSMUSP00000124511}. SQ SEQUENCE 957 AA; 109339 MW; 7B143361145BBC29 CRC64; XLASQPALAS SRVCFPERIL EDCGFDEQQE FRSRCSSVTG VMQKKVHENN QKTQPRRRHA SAPSHVQPSD SEKNRTMLFQ VGRFEINLIS PDTKSVVLEK NFKDISSCSQ GIKHVDHFGF ICRESPEPGL SQYICYVFQC ANESLVDEVM LTLKQAFSTA AALQSAKTQI KLCETCPMHS LHKLCERIEG LYPPRAKLVI QRHLSSLTDN EQADIFERVQ KMKPISDQEE NELVILHLRQ LCEAKQRTHV HIGEGPAIIS NSTIPENVTS GGRFKLDVLK NKAKRSLTSS LENIFSRGAN RMRGRLGSMD SFERANSLAS EKDFSPGDSP PGTPPASPLS SAWHAFPEED SDSPQFRRRA HTFSHPPSSS RRKLNLQDGK AHGLRSPLLR QSSSEQCSDG EGRKRTSSTC SNESLNAGGT PVTPRRVSWR QRIFLRVASP VNKSPSAMQQ QKDGLDRTEL LPLSPLSPTM EEEPLIIFLS GDEDTEKVEE KKKSKELKSL WKKAIHQQIL LLRMEKENQK LEEARRDELQ SRKVKLDYEE VGTCQKEILI AWDKKLLNCR TKIRCDMEDI HTSLKEGVPK SRRGEIWQFL ALQYRLRHRL PNKHQPPDTS YKELLKQLTA QQHAILVDLG RTFPTHPYFS VQLGAGQLSL FNLLKAYSLL DKEVGYCQGI SFVAGVLLLH MSEEQAFEML KFLMYDLGFR KQYRPDMMSL QIQMYQLSRL LHDYHRELYN HLEENEISPS LYAAPWFLTL FASQFPLGFV ARVFDIIFLQ GTEVIFKVAL SLLSSQEALI MECENFENIV EFLKSTLPDM NTTEMEKIIT QVFEMDISKQ LHAYEVEYHV LQDELLESSY ACEDNESLEK LERANNQLKR QNMDLLEKLQ VAHAKIQALE SNLETLLTRE TKMKALIRTL EQDKMAYQKT VEQIRKLLPA DALANCELLL KDLTHPTNDK AKAGNKP //