ID F6QTY0_MOUSE Unreviewed; 119 AA. AC F6QTY0; DT 18-APR-2012, integrated into UniProtKB/TrEMBL. DT 18-APR-2012, sequence version 1. DT 07-JAN-2015, entry version 21. DE SubName: Full=Trans-acting T-cell-specific transcription factor GATA-3 {ECO:0000313|Ensembl:ENSMUSP00000119730}; DE Flags: Fragment; GN Name=Gata3 {ECO:0000313|Ensembl:ENSMUSP00000119730, GN ECO:0000313|MGI:MGI:95663}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000119730, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000119730, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000119730, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000119730} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000119730}; RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000119730}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL845529; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL928704; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR PRIDE; F6QTY0; -. DR Ensembl; ENSMUST00000130615; ENSMUSP00000119730; ENSMUSG00000015619. DR MGI; MGI:95663; Gata3. DR GeneTree; ENSGT00760000119221; -. DR NextBio; 35556572; -. DR Proteomes; UP000000589; Chromosome 2. DR Bgee; F6QTY0; -. DR ExpressionAtlas; F6QTY0; baseline and differential. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0005730; C:nucleolus; IEA:Ensembl. DR GO; GO:0005634; C:nucleus; IDA:MGI. DR GO; GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IEA:Ensembl. DR GO; GO:0070888; F:E-box binding; IEA:Ensembl. DR GO; GO:0001158; F:enhancer sequence-specific DNA binding; IDA:MGI. DR GO; GO:0005134; F:interleukin-2 receptor binding; IPI:MGI. DR GO; GO:0046983; F:protein dimerization activity; IDA:MGI. DR GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IEA:Ensembl. DR GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:MGI. DR GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:MGI. DR GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:MGI. DR GO; GO:0043565; F:sequence-specific DNA binding; IDA:MGI. DR GO; GO:0003713; F:transcription coactivator activity; IDA:MGI. DR GO; GO:0048646; P:anatomical structure formation involved in morphogenesis; IMP:MGI. DR GO; GO:0007411; P:axon guidance; IMP:MGI. DR GO; GO:0001775; P:cell activation; IMP:MGI. DR GO; GO:0001709; P:cell fate determination; IDA:MGI. DR GO; GO:0048469; P:cell maturation; IMP:MGI. DR GO; GO:0000902; P:cell morphogenesis; IMP:MGI. DR GO; GO:0071773; P:cellular response to BMP stimulus; IDA:MGI. DR GO; GO:0071345; P:cellular response to cytokine stimulus; IDA:MGI. DR GO; GO:0035457; P:cellular response to interferon-alpha; IEA:Ensembl. DR GO; GO:0071353; P:cellular response to interleukin-4; IDA:MGI. DR GO; GO:0071356; P:cellular response to tumor necrosis factor; IEA:Ensembl. DR GO; GO:0048589; P:developmental growth; IMP:MGI. DR GO; GO:0035162; P:embryonic hemopoiesis; IMP:MGI. DR GO; GO:0048568; P:embryonic organ development; IMP:MGI. DR GO; GO:0030218; P:erythrocyte differentiation; IDA:MGI. DR GO; GO:0048872; P:homeostasis of number of cells; IMP:MGI. DR GO; GO:0006959; P:humoral immune response; IMP:MGI. DR GO; GO:0001701; P:in utero embryonic development; IMP:MGI. DR GO; GO:0042472; P:inner ear morphogenesis; IMP:MGI. DR GO; GO:0072643; P:interferon-gamma secretion; IMP:MGI. DR GO; GO:0072602; P:interleukin-4 secretion; IMP:MGI. DR GO; GO:0002088; P:lens development in camera-type eye; IMP:MGI. DR GO; GO:0072676; P:lymphocyte migration; IEA:Ensembl. DR GO; GO:0060374; P:mast cell differentiation; IDA:MGI. DR GO; GO:0060231; P:mesenchymal to epithelial transition; IEA:Ensembl. DR GO; GO:0001823; P:mesonephros development; IMP:MGI. DR GO; GO:0045786; P:negative regulation of cell cycle; IMP:MGI. DR GO; GO:2000146; P:negative regulation of cell motility; IEA:Ensembl. DR GO; GO:0008285; P:negative regulation of cell proliferation; IMP:MGI. DR GO; GO:2000352; P:negative regulation of endothelial cell apoptotic process; IEA:Ensembl. DR GO; GO:0045599; P:negative regulation of fat cell differentiation; IEA:Ensembl. DR GO; GO:0010629; P:negative regulation of gene expression; IMP:MGI. DR GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl. DR GO; GO:0032689; P:negative regulation of interferon-gamma production; IDA:MGI. DR GO; GO:0032703; P:negative regulation of interleukin-2 production; IDA:MGI. DR GO; GO:0033600; P:negative regulation of mammary gland epithelial cell proliferation; IEA:Ensembl. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI. DR GO; GO:0007399; P:nervous system development; IMP:MGI. DR GO; GO:0030182; P:neuron differentiation; IMP:MGI. DR GO; GO:0001764; P:neuron migration; IMP:MGI. DR GO; GO:0042421; P:norepinephrine biosynthetic process; IMP:MGI. DR GO; GO:0071599; P:otic vesicle development; IMP:MGI. DR GO; GO:0060017; P:parathyroid gland development; IMP:MGI. DR GO; GO:0035898; P:parathyroid hormone secretion; IMP:MGI. DR GO; GO:0045597; P:positive regulation of cell differentiation; IMP:MGI. DR GO; GO:0001819; P:positive regulation of cytokine production; IDA:MGI. DR GO; GO:0010595; P:positive regulation of endothelial cell migration; IEA:Ensembl. DR GO; GO:0032736; P:positive regulation of interleukin-13 production; IMP:MGI. DR GO; GO:2000667; P:positive regulation of interleukin-13 secretion; IEA:Ensembl. DR GO; GO:0032753; P:positive regulation of interleukin-4 production; IDA:MGI. DR GO; GO:0032754; P:positive regulation of interleukin-5 production; IMP:MGI. DR GO; GO:2000664; P:positive regulation of interleukin-5 secretion; IEA:Ensembl. DR GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl. DR GO; GO:0045582; P:positive regulation of T cell differentiation; IEA:InterPro. DR GO; GO:2000611; P:positive regulation of thyroid hormone generation; IEA:Ensembl. DR GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI. DR GO; GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IEA:Ensembl. DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:MGI. DR GO; GO:0009791; P:post-embryonic development; IMP:MGI. DR GO; GO:0002572; P:pro-T cell differentiation; IMP:MGI. DR GO; GO:0043370; P:regulation of CD4-positive, alpha-beta T cell differentiation; IMP:MGI. DR GO; GO:2000683; P:regulation of cellular response to X-ray; IEA:Ensembl. DR GO; GO:0042035; P:regulation of cytokine biosynthetic process; IDA:MGI. DR GO; GO:2000114; P:regulation of establishment of cell polarity; IDA:MGI. DR GO; GO:0061085; P:regulation of histone H3-K27 methylation; IDA:MGI. DR GO; GO:0051569; P:regulation of histone H3-K4 methylation; IDA:MGI. DR GO; GO:0043523; P:regulation of neuron apoptotic process; IMP:MGI. DR GO; GO:0010975; P:regulation of neuron projection development; IMP:MGI. DR GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI. DR GO; GO:0072001; P:renal system development; IGI:MGI. DR GO; GO:0042493; P:response to drug; IEA:Ensembl. DR GO; GO:0043627; P:response to estrogen; IEA:Ensembl. DR GO; GO:0045471; P:response to ethanol; IEA:Ensembl. DR GO; GO:0010332; P:response to gamma radiation; IEA:Ensembl. DR GO; GO:0009615; P:response to virus; IEA:Ensembl. DR GO; GO:0048485; P:sympathetic nervous system development; IMP:MGI. DR GO; GO:0030217; P:T cell differentiation; IDA:MGI. DR GO; GO:0033077; P:T cell differentiation in thymus; IMP:MGI. DR GO; GO:0045064; P:T-helper 2 cell differentiation; IDA:MGI. DR GO; GO:0045061; P:thymic T cell selection; IMP:MGI. DR GO; GO:0048538; P:thymus development; IMP:MGI. DR GO; GO:0001806; P:type IV hypersensitivity; IEA:Ensembl. DR GO; GO:0035799; P:ureter maturation; IMP:MGI. DR InterPro; IPR029521; GATA-3. DR PANTHER; PTHR10071:SF106; PTHR10071:SF106; 1. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT NON_TER 119 119 {ECO:0000313|Ensembl:ENSMUSP00000119730}. SQ SEQUENCE 119 AA; 12788 MW; B8092CD276F01BDF CRC64; MEAQYPLTEE VDVLFNIDGQ GNHVPSYYGN SVRATVQRYP PTHHGSQVCR PPLLHGSLPW LDGGKALSSH HTASPWNLSP FSKTSIHHGS PGPLSVYPPA SSSSLAAGHS SPHLFTFPP //