ID F6N686_SHEEP Unreviewed; 422 AA. AC F6N686; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 27-JUL-2011, sequence version 1. DT 10-MAY-2017, entry version 19. DE RecName: Full=Vasopressin V1b receptor {ECO:0000256|RuleBase:RU046427}; OS Ovis aries (Sheep). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; OC Pecora; Bovidae; Caprinae; Ovis. OX NCBI_TaxID=9940 {ECO:0000313|EMBL:AEG42503.1}; RN [1] {ECO:0000313|EMBL:AEG42503.1} RP NUCLEOTIDE SEQUENCE. RA Thompson D.J., Tariga H., Alagarsamy S., Vezza Alexander R., RA Croston G.E.; RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Receptor for arginine vasopressin. The activity of this CC receptor is mediated by G proteins which activate a phosphatidyl- CC inositol-calcium second messenger system. CC {ECO:0000256|RuleBase:RU046427}. CC -!- SUBCELLULAR LOCATION: Cell membrane CC {ECO:0000256|RuleBase:RU046427}; Multi-pass membrane protein CC {ECO:0000256|RuleBase:RU046427}. CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family. CC Vasopressin/oxytocin receptor subfamily. CC {ECO:0000256|RuleBase:RU046427}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JF940513; AEG42503.1; -; mRNA. DR RefSeq; NP_001233166.1; NM_001246237.1. DR RefSeq; NP_001233166.1; NM_001246237.1. DR RefSeq; NP_001233166.1; NM_001246237.1. DR UniGene; Oar.705; -. DR GeneID; 443050; -. DR KEGG; oas:443050; -. DR CTD; 553; -. DR KO; K04227; -. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0005000; F:vasopressin receptor activity; IEA:UniProtKB-UniRule. DR InterPro; IPR015076; DUF1856. DR InterPro; IPR000276; GPCR_Rhodpsn. DR InterPro; IPR017452; GPCR_Rhodpsn_7TM. DR InterPro; IPR001817; Vasoprsn_rcpt. DR InterPro; IPR000628; Vprs_rcpt_V1B. DR Pfam; PF00001; 7tm_1; 1. DR PRINTS; PR00237; GPCRRHODOPSN. DR PRINTS; PR00896; VASOPRESSINR. DR PRINTS; PR00897; VASOPRSNV1BR. DR SMART; SM01164; DUF1856; 1. DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1. DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1. PE 2: Evidence at transcript level; KW G-protein coupled receptor {ECO:0000256|RuleBase:RU046427}; KW Glycoprotein {ECO:0000256|RuleBase:RU046427}; KW Membrane {ECO:0000256|RuleBase:RU046427}; KW Receptor {ECO:0000256|RuleBase:RU046427, ECO:0000313|EMBL:AEG42503.1}; KW Transducer {ECO:0000256|RuleBase:RU046427}; KW Transmembrane {ECO:0000256|RuleBase:RU046427}; KW Transmembrane helix {ECO:0000256|RuleBase:RU046427}. FT TRANSMEM 38 59 Helical. {ECO:0000256|RuleBase:RU046427}. FT TRANSMEM 71 89 Helical. {ECO:0000256|RuleBase:RU046427}. FT TRANSMEM 109 130 Helical. {ECO:0000256|RuleBase:RU046427}. FT TRANSMEM 151 174 Helical. {ECO:0000256|RuleBase:RU046427}. FT TRANSMEM 199 222 Helical. {ECO:0000256|RuleBase:RU046427}. FT TRANSMEM 284 306 Helical. {ECO:0000256|RuleBase:RU046427}. FT TRANSMEM 318 341 Helical. {ECO:0000256|RuleBase:RU046427}. FT DOMAIN 51 338 G_PROTEIN_RECEP_F1_2. FT {ECO:0000259|PROSITE:PS50262}. SQ SEQUENCE 422 AA; 46449 MW; 9BEECC20E323DFF0 CRC64; MDSRPPWTAA PTSGSTVAAA NATTPWLGRD EELARVEIGV LATVLALATG GNLTVLLTVG QPVRKRSRMQ VFVLHLALTD LGVALFQVLP QLLWDITYRF RGPDPLCRAV KYLQVLSMFA STYMLLAMTL DRYLAVCHPL RSLQQPSRST YPLIAAPWLL AAVLSLPQVF IFSLREVIQG SGVLDCWADF RFPWGPRAYI TWTTLAIFIL PVAMLTACYS LICHEICKNL KVKTEAGQAE GGSWALRTGH LLSCPVAATR GLPSRVSSVS TISRAKIRTV KMTFVIVLAY IACWAPFFSV QMWSVWDENA PDEDSTNVAF TISMLLGNLS SCCNPWIYMG FNSHLWWRAL RRLACCRGAG PRMRRRLSNG SLSSRHATLL TRSSGLPARG LSPGLSRKPG PRDSLRGTEQ VDGDAATETS IF //