ID F5CPM3_9GEMI Unreviewed; 132 AA. AC F5CPM3; DT 28-JUN-2011, integrated into UniProtKB/TrEMBL. DT 28-JUN-2011, sequence version 1. DT 27-NOV-2024, entry version 18. DE RecName: Full=Replication enhancer {ECO:0000256|RuleBase:RU363029}; DE Short=REn {ECO:0000256|RuleBase:RU363029}; OS Euphorbia yellow mosaic virus - Goias [Brazil:DF:Taquara 8880:2009]. OC Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Repensiviricetes; OC Geplafuvirales; Geminiviridae; Begomovirus; Euphorbia yellow mosaic virus. OX NCBI_TaxID=1016870 {ECO:0000313|EMBL:AED02003.1}; RN [1] {ECO:0000313|EMBL:AED02003.1} RP NUCLEOTIDE SEQUENCE. RA Fernandes F.R., Albuquerque L.C., Oliveira C.L., Cruz A.R.R., Rocha W.B., RA Pereira T.G., Naito F.Y.B., Dias N.M., Nagata T., Faria J.C., Zerbini F.M., RA Aragao F.J.L., Inoue-Nagata A.K.; RT "Molecular and biological characterization of a new Brazilian begomovirus, RT Euphorbia yellow mosaic virus (EuYMV), infecting Euphorbia heterophylla RT plants."; RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Increases viral DNA accumulation. Enhances infectivity and CC symptom expression. {ECO:0000256|ARBA:ARBA00025603}. CC -!- SUBUNIT: Homooligomer. Interacts with the replication-associated CC protein (REP). Interacts with host proliferating cell nuclear antigen CC (PCNA). Interacts with host retinoblastoma-related protein 1 (RBR1), CC and may thereby deregulate the host cell cycle. Oligomerization and CC interaction with PCNA are necessary for optimal replication CC enhancement. {ECO:0000256|ARBA:ARBA00025955, CC ECO:0000256|RuleBase:RU363029}. CC -!- SIMILARITY: Belongs to the geminiviridae replication enhancer protein CC family. {ECO:0000256|ARBA:ARBA00009424, ECO:0000256|RuleBase:RU363029}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JF756673; AED02003.1; -; Genomic_DNA. DR Proteomes; UP001184085; Segment. DR GO; GO:0016032; P:viral process; IEA:InterPro. DR InterPro; IPR000657; Gemini_AL3. DR Pfam; PF01407; Gemini_AL3; 1. DR PRINTS; PR00231; GEMCOATAL3. PE 3: Inferred from homology; KW Host-virus interaction {ECO:0000256|ARBA:ARBA00022581, KW ECO:0000256|RuleBase:RU363029}. SQ SEQUENCE 132 AA; 15741 MW; 5A162F0CE3CB3E63 CRC64; MDLSTGEFIT VSQAENSVFI WEVPNPLYFK IIRVEDPIYT SLRIYHIQIR FNYNLRRALN LRKAFLNFQV WTTSIRASGM TYLSRFRHLV LMYLDQLGVV GLNHVIRAVR FATDRSYVND VLENHEIKFN FY //