ID F5CPM3_9GEMI Unreviewed; 132 AA. AC F5CPM3; DT 28-JUN-2011, integrated into UniProtKB/TrEMBL. DT 28-JUN-2011, sequence version 1. DT 05-JUN-2019, entry version 10. DE RecName: Full=Replication enhancer {ECO:0000256|RuleBase:RU363029}; DE Short=REn {ECO:0000256|RuleBase:RU363029}; OS Euphorbia yellow mosaic virus - Goias [Brazil:DF:Taquara 8880:2009]. OC Viruses; Geminiviridae; Begomovirus. OX NCBI_TaxID=1016870 {ECO:0000313|EMBL:AED02003.1}; RN [1] {ECO:0000313|EMBL:AED02003.1} RP NUCLEOTIDE SEQUENCE. RA Fernandes F.R., Albuquerque L.C., Oliveira C.L., Cruz A.R.R., RA Rocha W.B., Pereira T.G., Naito F.Y.B., Dias N.M., Nagata T., RA Faria J.C., Zerbini F.M., Aragao F.J.L., Inoue-Nagata A.K.; RT "Molecular and biological characterization of a new Brazilian RT begomovirus, Euphorbia yellow mosaic virus (EuYMV), infecting RT Euphorbia heterophylla plants."; RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Enhances infectivity and symptom expression. CC {ECO:0000256|RuleBase:RU363029}. CC -!- FUNCTION: Increases viral DNA accumulation. CC {ECO:0000256|RuleBase:RU363029}. CC -!- SUBUNIT: Homooligomer. Interacts with the replication-associated CC protein (REP). Interacts with host proliferating cell nuclear CC antigen (PCNA). Interacts with host retinoblastoma-related protein CC 1 (RBR1), and may thereby deregulate the host cell cycle. CC Oligomerization and interaction with PCNA are necessary for CC optimal replication enhancement. {ECO:0000256|RuleBase:RU363029}. CC -!- SIMILARITY: Belongs to the geminiviridae replication enhancer CC protein family. {ECO:0000256|RuleBase:RU363029}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JF756673; AED02003.1; -; Genomic_DNA. DR GO; GO:0016032; P:viral process; IEA:UniProtKB-KW. DR InterPro; IPR000657; Gemini_AL3. DR Pfam; PF01407; Gemini_AL3; 1. DR PRINTS; PR00231; GEMCOATAL3. DR ProDom; PD001172; Gemini_AL3; 1. PE 3: Inferred from homology; KW Host-virus interaction {ECO:0000256|RuleBase:RU363029}. SQ SEQUENCE 132 AA; 15741 MW; 5A162F0CE3CB3E63 CRC64; MDLSTGEFIT VSQAENSVFI WEVPNPLYFK IIRVEDPIYT SLRIYHIQIR FNYNLRRALN LRKAFLNFQV WTTSIRASGM TYLSRFRHLV LMYLDQLGVV GLNHVIRAVR FATDRSYVND VLENHEIKFN FY //