ID F5B6X3_PINMG Unreviewed; 626 AA. AC F5B6X3; DT 28-JUN-2011, integrated into UniProtKB/TrEMBL. DT 28-JUN-2011, sequence version 1. DT 31-JUL-2019, entry version 25. DE SubName: Full=Nacrein B4 {ECO:0000313|EMBL:AEC03972.1}; OS Margaritifera margaritifera (Freshwater pearl mussel). OC Eukaryota; Metazoa; Lophotrochozoa; Mollusca; Bivalvia; Pteriomorphia; OC Pterioida; Pterioidea; Pteriidae; Pinctada. OX NCBI_TaxID=102329 {ECO:0000313|EMBL:AEC03972.1}; RN [1] {ECO:0000313|EMBL:AEC03972.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=21040589; DOI=10.1186/1471-2164-11-613; RA Joubert C., Piquemal D., Marie B., Manchon L., Pierrat F., RA Zanella-Cleon I., Cochennec-Laureau N., Gueguen Y., Montagnani C.; RT "Transcriptome and proteome analysis of Pinctada margaritifera RT calcifying mantle and shell: focus on biomineralization."; RL BMC Genomics 11:613-613(2010). CC -!- SIMILARITY: Belongs to the alpha-carbonic anhydrase family. CC {ECO:0000256|SAAS:SAAS01166493}. CC -!- CAUTION: Lacks conserved residue(s) required for the propagation CC of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01134}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; HQ654772; AEC03972.1; -; mRNA. DR GO; GO:0004089; F:carbonate dehydratase activity; IEA:InterPro. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR Gene3D; 3.10.200.10; -; 2. DR InterPro; IPR001148; CA_dom. DR InterPro; IPR036398; CA_dom_sf. DR InterPro; IPR023561; Carbonic_anhydrase_a-class. DR PANTHER; PTHR18952; PTHR18952; 2. DR Pfam; PF00194; Carb_anhydrase; 2. DR SMART; SM01057; Carb_anhydrase; 1. DR SUPFAM; SSF51069; SSF51069; 1. DR PROSITE; PS51144; ALPHA_CA_2; 1. PE 2: Evidence at transcript level; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1 22 {ECO:0000256|SAM:SignalP}. FT CHAIN 23 626 {ECO:0000256|SAM:SignalP}. FT /FTId=PRO_5003326236. FT DOMAIN 55 626 Alpha-carbonic anhydrase. FT {ECO:0000259|PROSITE:PS51144}. FT REGION 265 485 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 265 477 Polar. {ECO:0000256|SAM:MobiDB-lite}. SQ SEQUENCE 626 AA; 69054 MW; 9E388D165924AEF4 CRC64; MWRMTTLLHL TSLLVLIPLC HCASMHRHDH YMDMDKTYRN RWGNCHYSGG SSCDAGFSYN REQSEEQCHG PYDWHTISSC FKACGSKERQ SPINIWSHRA LFRHKLPRLK FKPHMKSLDT KVSNHQNHAP EFDSEDEKLH VKLKNLVDGH YKFRNLHIHI GKSRRKGSEH SVDRHFTPME AHLVFRHDEK KEIKPSRIWL GRNFSGINEF VVVGVFLEVG DEGYGDEPDD DECKRILKGH YDHCDNNGDN GYNCDNGNNE NNGNNGNGNN GYNGNNGDNG NGNNGYNGNN GYNGNNGDNG NSGNNGNGNN GYNGNNGDNG NGNNGYNGNN GYNGNNGDNG NSRNNGNGNN GYNGNNGDNG NNRNNGNGNN GYNGNNGDDG NNGNNGNGNN GNNGYGNNGN NGNNGNGNNG NNGNGNNGNN GNGNNGNNGG NGNNGNGNNG NNGNGDYGSN GNNGGNGNNG NNGDNGNGDN GYNGDNGNSD GRPRRWDLEN VRRMHTERYH FSGRCIVKKA KRLSRILECA YRHKKVREFK RNGEHKSLDV EITPEMVLPP IKYRQYYTYE GSLTTPPCNE TVLWVVEKCH VQVSRRVLDA LRKVEGYDDG TTLSKFGTRR PTQRNIKPVP VYKNFI //